Model

MIMIC

MIMIC represents DNA, RNA, protein and associated molecular measurements in a shared multimodal model.

Sources (4)

polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens

Results are available for configurations using this model. Their fitted heads, extra inputs and evaluation settings are kept separate below.

1 evaluated configuration using this model

How it worksMIMIC workflow

Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation.

Sources (4)

Overview

Model type

Multimodal biomolecular transformer encoder-decoder

Sources (4)

Inputs

Co-observed molecular modalities and optional text context, grouped into nucleic, protein and text tracks.

Sources (4)

Outputs

Embeddings or generated modalities, such as residue solvent accessibility or splice-site classes.

Sources (4)

Access

Official downloadable model/card and usage examples: https://huggingface.co/polymathic-ai/MIMIC

Sources (4)

Source reviewed · Automated source review, 2026-09-16. All specifications and missing details

Related configurations, pipelines and services

These configurations, services and pipelines use this model within their own configurations. Their results, where available, are not assigned to the underlying model.

MIMIC Pipeline · 7 metric rows

Use this model

How it works, versions and access

How it works

MIMIC represents DNA, RNA, protein and associated molecular measurements in a shared multimodal model. Transformer encoder-decoder: 20 encoder layers and 12 decoder layers, width 1,536, rotary positional embeddings, mixed attention and five register tokens. The documented inputs are co-observed molecular modalities and optional text context, grouped into nucleic, protein and text tracks. The output consists of embeddings or generated modalities, such as residue solvent accessibility or splice-site classes.

Sources (4)

Versions and reproducibility

MIMIC 1.0; load_pretrained(version="1.0") example. Training curriculum increases encoder context from 1k to 10k tokens; the released configuration specifies 10,000 input tokens and 1,000 target tokens.

Sources (4)

Strengths, limitations and unresolved questions

Strengths and limitations

Strengths supported by sources

The interface accepts partially observed modality sets and supports both embedding and conditional generation.
Sources (4)
polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens

Limitations and conditions

The paper identifies uneven modality coverage, missing biological measurements and limited encoder/decoder windows. Predictions for a missing modality remain model inferences rather than experimental observations.
Sources (4)
polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens

Profile review details

Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied.

Stable record: catalog-model-mimic

Specifications

Inputs, training, access and other details

Explanatory profile: source reviewed · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
Property	Description and evidence
Model type	Multimodal biomolecular transformer encoder-decoder Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Architecture	Transformer encoder-decoder: 20 encoder layers and 12 decoder layers, width 1,536, rotary positional embeddings, mixed attention and five register tokens. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Inputs	Co-observed molecular modalities and optional text context, grouped into nucleic, protein and text tracks. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Outputs	Embeddings or generated modalities, such as residue solvent accessibility or splice-site classes. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Parameters	Approximately 1.25 billion. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Known versions	MIMIC 1.0; load_pretrained(version="1.0") example. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Training data	LORE aligns approximately 15.5M proteins and 13M RNA transcripts from over 6,000 organisms with associated molecular measurements and over 4B text tokens. Missing modalities are retained as partially observed examples. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Training cutoff	LORE protein/transcript linking uses UniProt release 2024_04. This component version does not establish a common latest-data date for all molecular and text tracks. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Context limits	Training curriculum increases encoder context from 1k to 10k tokens; the released configuration specifies 10,000 input tokens and 1,000 target tokens. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Weights licence	MIT; model card explicitly covers both model and source code. Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Access	Official downloadable model/card and usage examples: https://huggingface.co/polymathic-ai/MIMIC Sources (4) polymathic-ai/MIMIC: README.md; polymathic-ai/MIMIC: config.json; PolymathicAI/MIMIC: README.md; mimic: Primary paper PDF · MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens
Code licence	MIT Sources PolymathicAI/MIMIC: LICENSE · LICENSE: licence text

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

77 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-23-2b89723c6dd9
Property and statement	Original source and location	Review and provenance
Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims	mimic: Primary paper PDF Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2604.24506v1 Retrieved: 2026-09-16T20:04:04.776851+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.caption` Source artifact SHA-256: `0ba8639b263f0e7f736bbd4564a8b1acca1f66acc4300cffd3c26e6bf2e93ffe` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims	polymathic-ai/MIMIC: config.json Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 72e63a1ece34928422fd46f89b6a6580ace99a97 Retrieved: 2026-09-16T19:46:20.846683+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.caption` Source artifact SHA-256: `687e182e410fbfa235e24c337f51411c6fff583d3135fdbac202b08b0e63a8ef` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims	polymathic-ai/MIMIC: README.md Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 72e63a1ece34928422fd46f89b6a6580ace99a97 Retrieved: 2026-09-16T19:46:20.846683+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.caption` Source artifact SHA-256: `462acc643cba24d1d4c6f1419838402c5f3196e94260039baf61a59ef0a0a107` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims	PolymathicAI/MIMIC: README.md Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 9e652f16491e6c2e3881111e24b285c288554275 Retrieved: 2026-09-16T20:04:02.231308+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.caption` Source artifact SHA-256: `694bed54356d27cf087890ed80649c08ef4520a0eb5c85374a7347138a6cbb2f` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram steps Observed modalities Shared encoder Track-aware decoder Embeddings or generated tracks Individual claims	mimic: Primary paper PDF Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2604.24506v1 Retrieved: 2026-09-16T20:04:04.776851+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.steps` Source artifact SHA-256: `0ba8639b263f0e7f736bbd4564a8b1acca1f66acc4300cffd3c26e6bf2e93ffe` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram steps Observed modalities Shared encoder Track-aware decoder Embeddings or generated tracks Individual claims	polymathic-ai/MIMIC: config.json Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 72e63a1ece34928422fd46f89b6a6580ace99a97 Retrieved: 2026-09-16T19:46:20.846683+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.steps` Source artifact SHA-256: `687e182e410fbfa235e24c337f51411c6fff583d3135fdbac202b08b0e63a8ef` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram steps Observed modalities Shared encoder Track-aware decoder Embeddings or generated tracks Individual claims	polymathic-ai/MIMIC: README.md Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 72e63a1ece34928422fd46f89b6a6580ace99a97 Retrieved: 2026-09-16T19:46:20.846683+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.steps` Source artifact SHA-256: `462acc643cba24d1d4c6f1419838402c5f3196e94260039baf61a59ef0a0a107` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram steps Observed modalities Shared encoder Track-aware decoder Embeddings or generated tracks Individual claims	PolymathicAI/MIMIC: README.md Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 9e652f16491e6c2e3881111e24b285c288554275 Retrieved: 2026-09-16T20:04:02.231308+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.steps` Source artifact SHA-256: `694bed54356d27cf087890ed80649c08ef4520a0eb5c85374a7347138a6cbb2f` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram title MIMIC workflow Individual claims	mimic: Primary paper PDF Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2604.24506v1 Retrieved: 2026-09-16T20:04:04.776851+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.title` Source artifact SHA-256: `0ba8639b263f0e7f736bbd4564a8b1acca1f66acc4300cffd3c26e6bf2e93ffe` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram title MIMIC workflow Individual claims	polymathic-ai/MIMIC: config.json Original source ↗ MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 72e63a1ece34928422fd46f89b6a6580ace99a97 Retrieved: 2026-09-16T19:46:20.846683+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.title` Source artifact SHA-256: `687e182e410fbfa235e24c337f51411c6fff583d3135fdbac202b08b0e63a8ef` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact

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Sources and history

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Release 2026-09-23-2b89723c6dd9 · Record review: discovered

6 source records and release history

MIMIC official resource · Original source · Not reported
polymathic-ai/MIMIC: README.md · Original source · 72e63a1ece34928422fd46f89b6a6580ace99a97
polymathic-ai/MIMIC: config.json · Original source · 72e63a1ece34928422fd46f89b6a6580ace99a97
PolymathicAI/MIMIC: README.md · Original source · 9e652f16491e6c2e3881111e24b285c288554275
mimic: Primary paper PDF · Original source · 2604.24506v1
PolymathicAI/MIMIC: LICENSE · Original source · 9e652f16491e6c2e3881111e24b285c288554275

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Technical metadata and extraction receipts

Stable ID: catalog-model-mimic

areas: rna-transcriptomes; proteins-complexes
method types: foundation model
entity level: family
version: 1.0
reported name: MIMIC
access: Public MIT code and 1.25B-parameter weights; large local memory requirement.
method type: foundation model
historical missing metadata: checkpoint revision: not_yet_extracted; training data: not_yet_extracted; licence: not_yet_extracted
metadata review scope: historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
entity classification: review date: 2026-09-17; rationale: The cited profile describes a named learned biological predictor or representation model/family. Preserve this identity separately from task-specific fitting, individual checkpoints, pipelines and hosted access.; source ids: evidence-official-af8da643e933eae36a68; evidence-official-4565e66fdeb787b99afa; evidence-official-c14c0e6a0fdbe1479658; evidence-official-0ffe1031786a71400ffd; source locator: MIMIC paper Section 3 and Discussion; official model-card Architecture and License; config.json num_input_tokens and num_target_tokens; ambiguities: None recorded

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