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Paper-reported evidence

Inflammation-linked aging signals in frozen single-cell foundation models: donor-aware detection and robustness testing

2026 · Peer-reviewed · PMC archival version PMC13407579.1

Paper-reported results. The values below come from this source, not an independent rewire.it run.

Open primary paper →DOI: 10.1007/s10522-026-10471-8

Primary full text verified using Europe PMC XML; venue: Biogerontology; PMC ID: PMC13407579.

2 verified numerical rows · source checked 2026-09-15

Paper-reportedIndependent paper evaluation

Best frozen single-cell foundation model

Donor-aware age-class prediction

Reported score
0.322± 0.008 standard deviation
Metric
Balanced accuracy
Dataset / split
AIDA v2 PBMC cohort 622 donors

Same donor-aware splits and logistic-regression probe as expression PCA; text names Geneformer as best model on AIDA v2.

Table 2, AIDA v2 row, scFM BA ± SD columnVerify at source →
Paper-reportedIndependent paper evaluation

Gene-expression PCA

Donor-aware age-class prediction

Reported score
0.384
Metric
Balanced accuracy
Dataset / split
AIDA v2 PBMC cohort 622 donors

Fifty-component gene-expression PCA with the same donor-aware probe splits.

Table 2, AIDA v2 row, Gene-expr BA columnVerify at source →