rewire.it
Omics and molecular biology

Biological model benchmark database

Find models, understand how they are tested, and inspect the evidence behind their results.

Supporting records

Model families and reported methods, linked to their evaluations and sources. Versions are kept distinct where known.

226 matching records · Release 2026-09-16-d74d282221a9

model · discovered

AlphaFold 3 Server

AlphaFold 3 Server is a candidate method in the molecular-interactions catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

molecular-interactions · 1 linked sources

model · discovered

AlphaGenome

AlphaGenome is a candidate method in the dna-genomes catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

dna-genomes · 1 linked sources

model · discovered

Boltz-2

Boltz is a biomolecular interaction model family. Boltz-2 adds affinity prediction to complex-structure prediction.

molecular-interactions · 1 linked sources

model · discovered

Chai-1

Chai-1 is a candidate method in the proteins-complexes, molecular-interactions catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

proteins-complexes · molecular-interactions · 1 linked sources

model · discovered

DiffDock-L

DiffDock-L is a candidate method in the molecular-interactions catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

molecular-interactions · 1 linked sources

model · discovered

DNABERT-2

DNABERT-2 is a DNA encoder pretrained on sequences from multiple species. It supplies representations that can be adapted to genomic tasks.

dna-genomes · 1 linked sources

model · discovered

ESM-2

ESM-2 is a family of protein sequence transformers that produce residue-level and sequence-level representations.

proteins-complexes · 1 linked sources

model · discovered

ESMFold

ESMFold predicts protein structures from individual amino-acid sequences using an ESM-2 representation model and a folding system.

proteins-complexes · 1 linked sources

model · discovered

Evo 2

Evo 2 models and generates DNA at nucleotide resolution using the StripedHyena 2 architecture.

dna-genomes · microbes-communities · 1 linked sources

model · discovered

GEARS

GEARS predicts transcriptional responses to genetic perturbations using single-cell perturbation-screen data.

cells-tissues · 1 linked sources

model · discovered

Geneformer

Geneformer is a candidate method in the cells-tissues catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

cells-tissues · 1 linked sources

model · discovered

Kraken2

Kraken2 is a candidate method in the microbes-communities catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

microbes-communities · 1 linked sources

model · discovered

METAGENE-1

METAGENE-1 is a candidate method in the microbes-communities catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

microbes-communities · 1 linked sources

model · discovered

MetaPhlAn

MetaPhlAn is a candidate method in the microbes-communities catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

microbes-communities · 1 linked sources

model · discovered

MIMIC

MIMIC is a candidate method in the rna-transcriptomes, proteins-complexes catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

rna-transcriptomes · proteins-complexes · 1 linked sources

model · discovered

mRNA-FM

mRNA-FM is the coding-sequence extension of RNA-FM, intended to represent messenger RNA coding regions.

rna-transcriptomes · 1 linked sources

model · discovered

Nucleotide Transformer v2

Nucleotide Transformer v2 is a candidate method in the dna-genomes catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

dna-genomes · 1 linked sources

model · discovered

Pangolin

Pangolin predicts changes in splice-site strength from DNA variants. It accepts variant files or custom sequence inputs.

dna-genomes · 1 linked sources

model · discovered

ProkBERT

ProkBERT is a candidate method in the microbes-communities catalogue. The linked resource identifies the project; a checkpoint-level profile has not yet been extracted.

microbes-communities · 1 linked sources

model · discovered

ProteinMPNN

ProteinMPNN designs amino-acid sequences for a supplied protein backbone, with controls for fixed residues and chains.

proteins-complexes · 1 linked sources

About the evidence

Published evaluations and rewire evaluations are records in the same database, with their origin shown beside each result. This release includes 155 source-checked literature result rows and 12 metric rows from existing rewire runs.

Source checked does not mean independently reproduced. Comparisons require compatible data, protocols and metrics. Missing details stay visible.

Rewire evaluations

Read the protocol, coverage and limitations behind our corrected splice-variant evaluation.

MFASS v2 evaluation →

Correction history

MFASS v1 is superseded. Its original tables and methods remain available as an archived report.

Archived MFASS v1 report →
Collection coverage and remaining gaps

This is a dated collection, not an exhaustive model census. Model records include families and paper-specific methods; counts do not represent unique checkpoints.

{
  "profile_coverage": {
    "total": 396,
    "reviewed": 86,
    "limited": 310
  },
  "changelog": [
    "Add sourced explanatory model and benchmark profiles and API query support; existing result values and IDs remain unchanged.",
    "Profile review status is independent of numerical-result review; unresolved scientific metadata remains explicit."
  ],
  "research_lanes": 9,
  "search_entries": 11,
  "legacy_papers": 100,
  "legacy_result_rows": 149,
  "source_inputs": [
    {
      "file": "data/omics/migrated.jsonl",
      "sha256": "3c2b88985f8419b9e5eb1b24a603b689891b969d30819e4a84d2af62a4760628"
    },
    {
      "file": "data/omics/discovery.jsonl",
      "sha256": "dbc2fe14ed474144442b6b8cc07147e2a23eb3a865a3324e9b8a958706ea65a0"
    },
    {
      "file": "data/omics/model-profiles.jsonl",
      "sha256": "d9a9d985d605f0972c56d49d219ee4b9d623ebcc9fc6c98db58a57ad91a9466c"
    },
    {
      "file": "data/omics/benchmark-profiles.jsonl",
      "sha256": "7c5dc9cf17ea42c283ca298449b3646b7ee06161a2a67ab111e59a4d6c2f5479"
    },
    {
      "file": "data/omics/model-profile-associations.jsonl",
      "sha256": "7bd9f5fa2fe00f160ae53c5dff87352bfe4fbfd85162b712a864f390f41fcfc3"
    },
    {
      "file": "data/omics/benchmark-profile-associations.jsonl",
      "sha256": "1d5338137bf6ec14b7a059298648f1aeef58e346cc5b8f0bee0e539568a608ff"
    }
  ],
  "total_records": 1254,
  "public_records": 1227,
  "counts": {
    "model": 226,
    "benchmark": 170,
    "dataset": 101,
    "baseline": 27,
    "evaluation": 159,
    "result": 167,
    "source": 199,
    "claim": 178
  },
  "quarantined_results": 0,
  "scope_excluded_records": 27,
  "source_checked_results": 155,
  "rewire_result_rows": 12,
  "scope": "Specialist omics and molecular models; no clinical assistants or standalone medical imaging.",
  "limitation": "A dated discovery and source-transcription review, not an exhaustive census or independent reproduction of external experiments."
}

Download the database

Release 2026-09-16-d74d282221a9 · 2026-09-16

Original literature downloads

The original 100-paper collection is retained for citation history. These files include six result rows excluded from the current omics scope; use the database release above for the reviewed collection.