Gene-MTEB
Genomic embedding evaluations covering sequence classification and clustering. Accuracy and V-measure remain separate metrics and each source task retains its own comparison.
Overview
Genomic embedding evaluations covering sequence classification and clustering. Accuracy and V-measure remain separate metrics and each source task retains its own comparison.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Results
Each comparison retains its reviewed evaluation scope, dataset and metric. Results are shown without a pooled ranking.
Gene-MTEB genomic embedding benchmark HMPD-disease: HMPD-disease genomic embedding evaluation
accuracy (fraction) · Higher values are better.
Every method Gene-MTEB genomic embedding benchmark reports on HMPD-disease genomic embedding evaluation, scored with accuracy on HMPD-disease Gene-MTEB data used in METAGENE-1 Table 3.
Gene-MTEB genomic embedding benchmark HMPD-disease: HMPD-disease genomic embedding evaluation · HMPD-disease Gene-MTEB data used in METAGENE-1 Table 3 (Gene-MTEB genomic embedding benchmark split)
Evidence origin: Author-reported evaluation. Numerical source review does not establish independent reproduction.
METAGENE-1 v1: Gene-MTEB complete component tasks · Table 3 (S5.T3), row HMPD-disease, column DNABERT-2; Section 5.3 paragraphs S5.SS3.p2.1 and S5.SS3.p3.1All 16 component tasks and five methods are included. Twenty-five printed aggregate cells are retained in a companion receipt, excluded from task-level result counts to avoid counting derived averages as extra experiments.
All comparison limitations (5)
- All 16 component tasks and five methods are included. Twenty-five printed aggregate cells are retained in a companion receipt, excluded from task-level result counts to avoid counting derived averages as extra experiments.
- Classification accuracy and clustering V-measure must not be combined into a universal performance metric.
- Paper source does not pin exact evaluator/data revisions or per-task denominators. Current code metadata uses mutable dataset revision main; its development metadata is not asserted to be the evaluated paper version.
- Paper calls embeddings zero-shot; this does not mean classification is label-free: logistic-regression probes use training labels.
- No uncertainty intervals or repeats are printed.
Automated source review: 2026-09-23.
No unavailable values; missing scores remain labelled and are never plotted as zero.
Showing 5 of 5 matching rows.
Dots show point estimates. Whiskers show only explicitly defined uncertainty (standard deviation, standard error or a labelled interval); their definitions remain in Table. Unresolved uncertainty is not plotted. Differences do not establish statistical significance.
Methods and evaluation design
Procedure, tasks and evaluated configurations
Evaluation design
Benchmarks bring together tasks and protocols. A task describes the biological question; a protocol defines a particular test.
Protocols
- Gene-MTEB genomic embedding benchmark HMPD-disease: HMPD-disease genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPD-sex: HMPD-sex genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPD-single: HMPD-single genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPD-source: HMPD-source genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-p2p: HMPR-p2p genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-s2s-align: HMPR-s2s-align genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-s2s-small: HMPR-s2s-small genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-s2s-tiny: HMPR-s2s-tiny genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-1: Human-Virus-1 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-2: Human-Virus-2 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-3: Human-Virus-3 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-4: Human-Virus-4 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-p2p: HVR-p2p genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-s2s-align: HVR-s2s-align genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-s2s-small: HVR-s2s-small genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-s2s-tiny: HVR-s2s-tiny genomic embedding evaluation
These source-backed links do not make different protocols or scores interchangeable.
Baseline coverage
Reference methods help show what a model adds beyond simple controls. We track a null control and a conventional method for each protocol.
0 of 32 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.
Baseline status by linked protocol
- Gene-MTEB genomic embedding benchmark HMPD-disease: HMPD-disease genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HMPD-sex: HMPD-sex genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HMPD-single: HMPD-single genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HMPD-source: HMPD-source genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HMPR-p2p: HMPR-p2p genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HMPR-s2s-align: HMPR-s2s-align genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HMPR-s2s-small: HMPR-s2s-small genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HMPR-s2s-tiny: HMPR-s2s-tiny genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark Human-Virus-1: Human-Virus-1 genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark Human-Virus-2: Human-Virus-2 genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark Human-Virus-3: Human-Virus-3 genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark Human-Virus-4: Human-Virus-4 genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HVR-p2p: HVR-p2p genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HVR-s2s-align: HVR-s2s-align genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HVR-s2s-small: HVR-s2s-small genomic embedding evaluation · 0/2 roles measured
- Gene-MTEB genomic embedding benchmark HVR-s2s-tiny: HVR-s2s-tiny genomic embedding evaluation · 0/2 roles measured
Protocol coverage CSV · Model evaluation matrix · Source table · Release and checksums
Coverage is derived from release 2026-09-23-2b89723c6dd9. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.
Run this benchmark
Choose a concrete protocol before running an evaluation. Its inputs, split and scoring rules determine which results can be compared.
- Gene-MTEB genomic embedding benchmark HMPD-disease: HMPD-disease genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPD-sex: HMPD-sex genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPD-single: HMPD-single genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPD-source: HMPD-source genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-p2p: HMPR-p2p genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-s2s-align: HMPR-s2s-align genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-s2s-small: HMPR-s2s-small genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HMPR-s2s-tiny: HMPR-s2s-tiny genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-1: Human-Virus-1 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-2: Human-Virus-2 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-3: Human-Virus-3 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark Human-Virus-4: Human-Virus-4 genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-p2p: HVR-p2p genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-s2s-align: HVR-s2s-align genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-s2s-small: HVR-s2s-small genomic embedding evaluation
- Gene-MTEB genomic embedding benchmark HVR-s2s-tiny: HVR-s2s-tiny genomic embedding evaluation
Run this benchmark
The paper describes frozen embedding probes and references Gene-MTEB. Rewire has no maintained runner for this published evaluation. Original split hashes, checkpoint revisions and evaluator revision are not established.
A maintained rewire runner has not been verified for this benchmark. Check data access, weights, licences, dependencies and hardware in the linked official documentation; requirements have not been fully extracted.
METAGENE-1 v1: Gene-MTEB complete component tasks · Section 5.3Strengths, limitations and unresolved questions
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
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Sources and history
View linked audit checks and correction history
Release 2026-09-23-2b89723c6dd9 · Record review: source checked
1 source records and release history
- METAGENE-1 v1: Gene-MTEB complete component tasks · Original source · arXiv:2501.02045v1
Technical metadata and extraction receipts
Stable ID: discovery-benchmark-gene-mteb
- areas
- genomics
- source locator
- METAGENE-1 Section 5.3; Table 3
- run documentation
- record id: discovery-benchmark-gene-mteb; status: source_reviewed_not_executed; source ids: coverage-source-metagene-paper-v1; source locator: Section 5.3; summary: The paper describes frozen embedding probes and references Gene-MTEB. Rewire has no maintained runner for this published evaluation. Original split hashes, checkpoint revisions and evaluator revision are not established.
- entity level
- suite
Related records
- part of: Gene-MTEB genomic embedding benchmark HMPD-disease: HMPD-disease genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HMPD-sex: HMPD-sex genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HMPD-single: HMPD-single genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HMPD-source: HMPD-source genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HMPR-p2p: HMPR-p2p genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HMPR-s2s-align: HMPR-s2s-align genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HMPR-s2s-small: HMPR-s2s-small genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HMPR-s2s-tiny: HMPR-s2s-tiny genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark Human-Virus-1: Human-Virus-1 genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark Human-Virus-2: Human-Virus-2 genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark Human-Virus-3: Human-Virus-3 genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark Human-Virus-4: Human-Virus-4 genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HVR-p2p: HVR-p2p genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HVR-s2s-align: HVR-s2s-align genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HVR-s2s-small: HVR-s2s-small genomic embedding evaluation
- part of: Gene-MTEB genomic embedding benchmark HVR-s2s-tiny: HVR-s2s-tiny genomic embedding evaluation