Strengths supported by sources
- Tests transfer between cellular contexts rather than interpolation among measured responses in one context.vcc2026 official source · Arc announcement, 20 August 2026: The 2026 task; Evaluation
benchmark · challenge
Virtual Cell Challenge 2026
The 2026 Virtual Cell Challenge tests perturbation prediction in unseen cellular contexts.
At a glance
Explanatory profile: source reviewed · Automated source review, 2026-09-16. This does not change the review status of its results.
| Property | Description and evidence |
|---|---|
| Record type | Prospective challengevcc2026 official source · Arc announcement, 20 August 2026: The 2026 task; Evaluation |
| Inputs | Unperturbed expression and CRISPRi target genesvcc2026 official source · Arc announcement, 20 August 2026: The 2026 task; Evaluation |
| Assessment | Held-out expression responses, scored with the challenge metric panelvcc2026 official source · Arc announcement, 20 August 2026: The 2026 task; Evaluation |
| Datasets | Not extracted or verified for this record. |
| Organisms | Not extracted or verified for this record. |
| Assays | Not extracted or verified for this record. |
| Splits | Not extracted or verified for this record. |
| Adaptation | Not extracted or verified for this record. |
| Baselines | Not extracted or verified for this record. |
How it works
Conceptual overview, not an executable specification.
Read the diagram as text
- Unperturbed cells and targets
- Predict CRISPRi response
- Withheld experimental response
- Apply challenge scorer
Procedure
Predict post-CRISPRi expression from non-targeting-control cells and target-gene identifiers. No challenge-specific training responses are released. Three cell lines support validation and three are reserved for final testing.
vcc2026 official source · Arc announcement, 20 August 2026: The 2026 task; EvaluationTested models and results
Release 2026-09-16-d74d282221a9 · 0 evaluations · 0 metric rows. Different protocols are not a single leaderboard.
No evaluations linked in this release.
Strengths and limitations
Limitations and conditions
- External training data are allowed; their provenance must be recorded. The final 2026 assessment is not yet available at this review date.vcc2026 official source · Arc announcement, 20 August 2026: The 2026 task; Evaluation
Profile review details
Primary-source description checked by an automated research assistant. This is profile review, not independent execution or numerical reproduction.
Stable record: discovery-benchmark-virtual-cell-challenge-2026Applicable tests and references
Applicability is distinct from a completed evaluation.
- STATE · Proposed association
Sources and history
Release 2026-09-16-d74d282221a9 · Record review: discovered
- vcc2026 official source · Original source · Not reported
Technical metadata and extraction receipts
Stable ID: discovery-benchmark-virtual-cell-challenge-2026
- areas
- single-cell
- entity level
- challenge
- missing metadata
- dataset release: unextracted; metric implementation: unextracted; split manifest: unextracted; version: unextracted
- scope note
- Specialist molecular or omics evaluation; protocol details require review before numerical comparison.
- task
- Zero-shot perturbation prediction in unseen cellular contexts
- version
- Not reported
Related records
- applicable to: STATE