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Benchmark

ESMFold2 Runs N’ Poses comparison

Bounded complete Figure 2C Runs N’ Poses subpanel: all eleven printed labels, separated into single-sequence and MSA comparisons.

11 evaluations · 11 metric rows

Overview

Bounded complete Figure 2C Runs N’ Poses subpanel: all eleven printed labels, separated into single-sequence and MSA comparisons.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Results

Each comparison retains its reviewed evaluation scope, dataset and metric. Results are shown without a pooled ranking.

ESMFold2 Runs N’ Poses reported comparison msa: Runs N’ Poses ligand pass rate (MSA)

ligand_pass_rate (percent) · Higher values are better.

Every method ESMFold2 Runs N’ Poses reported comparison reports on Runs N’ Poses ligand pass rate (MSA), scored with Ligand pass rate on Runs N’ Poses complete-case intersection: 2,573 scored ligands.

ESMFold2 Runs N’ Poses reported comparison msa: Runs N’ Poses ligand pass rate (MSA) · Runs N’ Poses complete-case intersection: 2,573 scored ligands (ESMFold2 Runs N’ Poses reported comparison split)

Evidence origin: Author-reported evaluation. Numerical source review does not establish independent reproduction.

ESMFold2 primary paper v1, Figure 2C Runs N’ Poses · Figure 2C right subpanel; Appendix A.2.10 Runs N’ Poses, PDF pages 5, 46–47

Author-reported integer-rounded labels from the original figure, not raw unrounded scores or independent reproductions. All 11 labelled bars in this subpanel are retained.

All comparison limitations (5)
  • Author-reported integer-rounded labels from the original figure, not raw unrounded scores or independent reproductions. All 11 labelled bars in this subpanel are retained.
  • The two panels separate single-sequence and MSA conditioning. Loop counts, inference settings and model versions remain in configuration labels.
  • n=2,573 counts scored ligands, not independent receptor systems. Results use the source’s complete-case intersection and omit ligands without defined SuCOS scores.
  • The source shows graphical ±1 sigma uncertainty from 200 bootstrap resamples. Exact error-bar values are not printed in this subpanel and remain unextracted; no numerical uncertainty was estimated.
  • The general OpenFold family record describes OpenFold/AlphaFold2; this OpenFold3 baseline receives no unsupported family link. Protenix-v1 also remains an independently named baseline.

Automated source review: 2026-09-23.

No unavailable values; missing scores remain labelled and are never plotted as zero.

Showing 7 of 7 matching rows.

Dots show point estimates. Whiskers show only explicitly defined uncertainty (standard deviation, standard error or a labelled interval); their definitions remain in Table. Unresolved uncertainty is not plotted. Differences do not establish statistical significance.

Methods and evaluation design

Procedure, tasks and evaluated configurations

Evaluation design

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Baseline coverage

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0 of 4 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.

Baseline status by linked protocol

Protocol coverage CSV · Model evaluation matrix · Source table · Release and checksums

Coverage is derived from release 2026-09-23-2b89723c6dd9. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.

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Run instructions

No runnable recipe has been reviewed for this benchmark. Dataset access, model requirements, licences and compute requirements must be checked against its sources before execution.

Strengths, limitations and unresolved questions

Evidence

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Evidence table

Inspect claims, sources and review details

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Claims, original sources and review scope · Release 2026-09-23-2b89723c6dd9
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Sources and history

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Release 2026-09-23-2b89723c6dd9 · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: model-coverage-esmfold2-runs-n-poses

areas
proteins-complexes
entity level
suite
source locator
Figure 2C right subpanel; Appendix A.2.10, PDF pages 5, 46–47
missing metadata
runner: unavailable; split manifest: unextracted
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