This paper-specific evaluation tests Antibody loop structure prediction using ImmuneBuilder antibody test set.
Explanatory profile: limited source coverage · Automated source review, 2026-09-16. This does not change the review status of its results.
| Property | Description and evidence |
|---|---|
| Record type | Paper-specific task; protocol incompletely extractedConformation-aware structure prediction of antigen-recognizing immune proteins · Table 1, Antibodies / Ibex row, CDR H3 column; Table 1, Antibodies / Chai-1 row, CDR H3 column |
| Inputs | ImmuneBuilder antibody test setConformation-aware structure prediction of antigen-recognizing immune proteins · Table 1, Antibodies / Ibex row, CDR H3 column; Table 1, Antibodies / Chai-1 row, CDR H3 column |
| Assessment | Mean CDR H3 RMSDConformation-aware structure prediction of antigen-recognizing immune proteins · Table 1, Antibodies / Ibex row, CDR H3 column; Table 1, Antibodies / Chai-1 row, CDR H3 column |
| Recorded split or evaluation setting | UnextractedConformation-aware structure prediction of antigen-recognizing immune proteins · Table 1, Antibodies / Ibex row, CDR H3 column; Table 1, Antibodies / Chai-1 row, CDR H3 column |
| Datasets | Not extracted or verified for this record. |
| Organisms | Not extracted or verified for this record. |
| Assays | Not extracted or verified for this record. |
| Adaptation | Not extracted or verified for this record. |
| Baselines | Not extracted or verified for this record. |
Outline of the existing paper extraction. Split membership, fitting details and scorer implementation remain incompletely reviewed.
The existing paper extraction describes: Backbone RMSD after framework alignment; average over antibody test structures.; Backbone RMSD after framework alignment; one seed and one diffusion trajectory. This description is retained with the exact evaluation records; it is not a new protocol reconstruction.
Conformation-aware structure prediction of antigen-recognizing immune proteins · Table 1, Antibodies / Ibex row, CDR H3 column; Table 1, Antibodies / Chai-1 row, CDR H3 columnRelease 2026-09-16-d74d282221a9 · 2 evaluations · 2 metric rows. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| Ibex: Antibody loop structure prediction Model: Ibex · Benchmark: Antibody loop structure prediction · Dataset: ImmuneBuilder antibody test set Backbone RMSD after framework alignment; average over antibody test structures. Author-reported evaluation · Evaluation metadata: needs review | ||
| 2.72 Mean CDR H3 RMSD Unit: Å · Direction: unknown | Uncertainty: not reported in legacy extract Scored: Not reported · Eligible: Not reported | source checkedConformation-aware structure prediction of antigen-recognizing immune proteins · Table 1, Antibodies / Ibex row, CDR H3 column Source checking is not independent reproduction. |
| Chai-1: Antibody loop structure prediction Model: Chai-1 · Benchmark: Antibody loop structure prediction · Dataset: ImmuneBuilder antibody test set Backbone RMSD after framework alignment; one seed and one diffusion trajectory. Independent external evaluation · Evaluation metadata: needs review | ||
| 2.65 Mean CDR H3 RMSD Unit: Å · Direction: unknown | Uncertainty: not reported in legacy extract Scored: Not reported · Eligible: Not reported | source checkedConformation-aware structure prediction of antigen-recognizing immune proteins · Table 1, Antibodies / Chai-1 row, CDR H3 column Source checking is not independent reproduction. |
Catalogue extraction inspected; protocol claims remain limited to the cited evidence. Missing details are not presumed absent from the original paper.
Stable record: reported-task-f3a12dbc0e0439Release 2026-09-16-d74d282221a9 · Record review: needs review
Stable ID: reported-task-f3a12dbc0e0439