Proteus on Genie 3 short monomer generation novelty-afdb: Unconditional short monomer Novelty, AFDB
Genie 3 short monomer generation evaluation of Proteus on Unconditional short monomer Novelty, AFDB, scored with Novelty, AFDB.
Evaluation results
1 evaluation · 1 metric rows. Different protocols are not a single leaderboard.
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| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Proteus | Protocol: Genie 3 short monomer generation novelty-afdb: Unconditional short monomer Novelty, AFDB Dataset subset: 500 generated monomers per run; lengths 50–250 in steps of 50; three runs (Genie 3 short monomer generation split) | 0.37 novelty_afdb reported score · higher Uncertainty: Not reported Coverage: generated per run: 500; repeats: 3; note: Three repeated runs; metric-specific valid subsets not assigned a pooled denominator. | Author-reported evaluation · source checkedMethods, coverage and sourceProteus on Genie 3 short monomer generation novelty-afdb: Unconditional short monomer Novelty, AFDB Unconditional short monomer generation: 100 structures at each length 50, 100, 150, 200 and 250 (500 samples per run); 3 repeated runs; Table 3 reports the authors’ average across runs. Designability uses minimum C-alpha scRMSD <2 angstrom across 8 ProteinMPNN sequences refolded with ESMFold. Diversity and novelty use FoldSeek release 10 (2025-01-19); exact definitions and reference sets in Appendix B.1. Method-specific checkpoints and sampling settings remain as Appendix B.2. Aggregation: Mean over three repeated runs Genie 3 primary paper v1, Table 3 · PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB |
Source checking is not independent reproduction. Release 2026-09-23-2b89723c6dd9.
Evaluation procedure
Unconditional short monomer generation: 100 structures at each length 50, 100, 150, 200 and 250 (500 samples per run); 3 repeated runs; Table 3 reports the authors’ average across runs. Designability uses minimum C-alpha scRMSD <2 angstrom across 8 ProteinMPNN sequences refolded with ESMFold. Diversity and novelty use FoldSeek release 10 (2025-01-19); exact definitions and reference sets in Appendix B.1. Method-specific checkpoints and sampling settings remain as Appendix B.2.
- Configuration
- Proteus
- Protocol
- Genie 3 short monomer generation novelty-afdb: Unconditional short monomer Novelty, AFDB
- Dataset subset
- 500 generated monomers per run; lengths 50–250 in steps of 50; three runs (Genie 3 short monomer generation split)
- origin
- Author-reported evaluation
- configuration
- Not reported
- protocol id
- genie3-2026-table3-task-novelty-afdb
- metric implementation
- Novelty, AFDB
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
Reproduction
- Split
- Not reported
- Adaptation
- Not reported
- Scoring implementation
- Novelty, AFDB
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
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Evidence table
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Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
15 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.adaptation Author-evaluated unconditional generation with method-specific released checkpoint and sampling settings; no additional training inferred. Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.metric_implementation Novelty, AFDB Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.protocol_id genie3-2026-table3-task-novelty-afdb Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.evaluation_group_id genie3-2026-table3-method-proteus-genie3-2026-table3-dataset-500-generated-monomers-per-run-lengths-50-250-in-steps-of-50-three-runs-evaluation-setup Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.evidence_overlap Five metrics from the same Table 3 generated sets are one evaluation setup; per-run Tables 4 and 5 repeat the same underlying experiment and are not independent evidence. Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.origin author_reported Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.protocol Unconditional short monomer generation: 100 structures at each length 50, 100, 150, 200 and 250 (500 samples per run); 3 repeated runs; Table 3 reports the authors’ average across runs. Designability uses minimum C-alpha scRMSD <2 angstrom across 8 ProteinMPNN sequences refolded with ESMFold. Diversity and novelty use FoldSeek release 10 (2025-01-19); exact definitions and reference sets in Appendix B.1. Method-specific checkpoints and sampling settings remain as Appendix B.2. Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.published_score_reproduction false Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.source_locator PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.suite_complete false Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
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Release 2026-09-23-2b89723c6dd9 · Record review: source checked
1 source records and release history
- Genie 3 primary paper v1, Table 3 · Original source · 10.64898/2026.05.01.722168v1; posted 2026-05-05
Technical metadata and extraction receipts
Stable ID: genie3-2026-table3-evaluation-proteus-novelty-afdb
- areas
- proteins-complexes
- tasks
- Unconditional short monomer Novelty, AFDB
- origin
- author_reported
- protocol
- Unconditional short monomer generation: 100 structures at each length 50, 100, 150, 200 and 250 (500 samples per run); 3 repeated runs; Table 3 reports the authors’ average across runs. Designability uses minimum C-alpha scRMSD <2 angstrom across 8 ProteinMPNN sequences refolded with ESMFold. Diversity and novelty use FoldSeek release 10 (2025-01-19); exact definitions and reference sets in Appendix B.1. Method-specific checkpoints and sampling settings remain as Appendix B.2.
- comparison
- protocol id: genie3-2026-table3-task-novelty-afdb; metric implementation: Novelty, AFDB
- missing metadata
- checkpoint revision: unreported; seeds: unreported; budget: unreported; split manifest: unextracted
- source locator
- PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB
- adaptation
- Author-evaluated unconditional generation with method-specific released checkpoint and sampling settings; no additional training inferred.
- evidence overlap
- Five metrics from the same Table 3 generated sets are one evaluation setup; per-run Tables 4 and 5 repeat the same underlying experiment and are not independent evidence.
- published score reproduction
- false
- suite complete
- false
- evaluation group id
- genie3-2026-table3-method-proteus-genie3-2026-table3-dataset-500-generated-monomers-per-run-lengths-50-250-in-steps-of-50-three-runs-evaluation-setup
Related records
- benchmark: Genie 3 short monomer generation novelty-afdb: Unconditional short monomer Novelty, AFDB
- model: Proteus
- dataset: 500 generated monomers per run; lengths 50–250 in steps of 50; three runs (Genie 3 short monomer generation split)
- evaluation: Proteus · Genie 3 short monomer generation novelty-afdb · Novelty, AFDB