ProGen2 XL on ProteinGym ZS-SUB-RECALL: Zero-shot substitutions, top 10% recall
ProteinGym evaluation of ProGen2 XL on Zero-shot substitutions, top 10% recall, scored with Top 10% recall.
Methods and reproduction
ProteinGym evaluation of ProGen2 XL on Zero-shot substitutions, top 10% recall, scored with Top 10% recall.
- task
- ProteinGym ZS-SUB-RECALL: Zero-shot substitutions, top 10% recall
- configuration
- ProGen2 XL
- dataset subset
- ProteinGym substitution DMS assays (ProteinGym split)
- Split
- Not reported
- Adaptation
- Not reported
- Scoring implementation
- Top 10% recall
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evaluation procedure
Zero-shot scoring of substitution assays, averaged over assays with the correction the paper describes.
- Configuration
- ProGen2 XL
- Task
- ProteinGym ZS-SUB-RECALL: Zero-shot substitutions, top 10% recall
- Dataset subset
- ProteinGym substitution DMS assays (ProteinGym split)
- origin
- Author-reported evaluation
- configuration
- Not reported
- protocol id
- proteingym-task-zs-sub-recall
- metric implementation
- Top 10% recall
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
Evaluation results
Release 2026-09-17-134cd1815de8 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| ProGen2 XL on ProteinGym ZS-SUB-RECALL: Zero-shot substitutions, top 10% recall Configuration: ProGen2 XLTask: ProteinGym ZS-SUB-RECALL: Zero-shot substitutions, top 10% recallDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Zero-shot scoring of substitution assays, averaged over assays with the correction the paper describes. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.199 recall Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Source checking is not independent reproduction. |
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
10 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.comparison.metric_implementation Top 10% recall Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| attributes.comparison.protocol_id proteingym-task-zs-sub-recall Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| attributes.origin author_reported Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| attributes.protocol Zero-shot scoring of substitution assays, averaged over assays with the correction the paper describes. Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| attributes.source_locator Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| description ProteinGym evaluation of ProGen2 XL on Zero-shot substitutions, top 10% recall, scored with Top 10% recall. Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| Relationship: benchmark proteingym-task-zs-sub-recall Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| Relationship: dataset proteingym-dataset-proteingym-substitution-dms-assays Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| Relationship: model proteingym-method-progen2-xl Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| name ProGen2 XL on ProteinGym ZS-SUB-RECALL: Zero-shot substitutions, top 10% recall Context-only references | ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall) Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
Sources and history
Release 2026-09-17-134cd1815de8 · Record review: source checked
1 source records and release history
- ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Original source · Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Technical metadata and extraction receipts
Stable ID: proteingym-evaluation-progen2-xl-zs-sub-recall
- areas
- proteins-complexes
- tasks
- Zero-shot substitutions, top 10% recall
- origin
- author_reported
- protocol
- Zero-shot scoring of substitution assays, averaged over assays with the correction the paper describes.
- comparison
- protocol id: proteingym-task-zs-sub-recall; metric implementation: Top 10% recall
- missing metadata
- checkpoint revision: unreported; seeds: unreported; budget: unreported; split manifest: unextracted
- source locator
- Table 2, row(ProGen2 XL), column(Zero-shot substitutions, top 10% recall)