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Evaluation

SegmentNT-3kb-single-task (x14) on SegmentNT human genome annotation protein coding gene auPRC: protein coding gene: per-nucleotide annotation (auPRC)

SegmentNT human genome annotation evaluation of SegmentNT-3kb-single-task (x14) on protein coding gene: per-nucleotide annotation (auPRC), scored with Area under precision-recall curve.

Evaluation results

1 evaluation · 1 metric rows. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: SegmentNT-3kb-single-task (x14)Protocol: SegmentNT human genome annotation protein coding gene auPRC: protein coding gene: per-nucleotide annotation (auPRC)
Dataset subset: Human genome protein coding gene test chromosomes 20 and 21 (SegmentNT human genome annotation split)
0.72 (± 0.001) auprc
dimensionless · higher

Uncertainty: type: standard_deviation; value: 0.001

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · source checked
Methods, coverage and source

SegmentNT-3kb-single-task (x14) on SegmentNT human genome annotation protein coding gene auPRC: protein coding gene: per-nucleotide annotation (auPRC)

Test chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons.

Aggregation: Not reported

SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Source checking is not independent reproduction. Release 2026-09-23-2b89723c6dd9.

Evaluation procedure

Test chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons.

Configuration
SegmentNT-3kb-single-task (x14)
Protocol
SegmentNT human genome annotation protein coding gene auPRC: protein coding gene: per-nucleotide annotation (auPRC)
Dataset subset
Human genome protein coding gene test chromosomes 20 and 21 (SegmentNT human genome annotation split)
origin
Author-reported evaluation
configuration
Not reported
protocol id
segmentnt-supplement-2025-task-protein-coding-gene-auprc
metric implementation
Area under precision-recall curve

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Not reported
Adaptation
Not reported
Scoring implementation
Area under precision-recall curve

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

16 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-23-2b89723c6dd9
Property and statementOriginal source and locationReview and provenance
attributes.adaptation
Task-specific supervised segmentation training; source-specific backbone and input length retained.
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.adaptation

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.metric_implementation
Area under precision-recall curve
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.protocol_id
segmentnt-supplement-2025-task-protein-coding-gene-auprc
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.evaluation_group_id
segmentnt-supplement-2025-method-segmentnt-3kb-single-task-x14-segmentnt-supplement-2025-dataset-human-genome-protein-coding-gene-test-chromosomes-20-and-21-evaluation-setup
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.evaluation_group_id

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.evidence_overlap
Tables 2 and 3 report different metrics over the same paper experiment set. They are not independent reproductions or replications.
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.evidence_overlap

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.origin
author_reported
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.origin

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.protocol
Test chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons.
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.protocol

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.published_score_reproduction
false
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.published_score_reproduction

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.same_paper_experiment_set
segmentnt-2025-human-genome-14-elements
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.same_paper_experiment_set

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.source_locator
Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene
Context-only references
SegmentNT supplementary information: complete Tables 2 and 3

Original source ↗

Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene

Version: Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
Retrieved: 2026-09-23T11:23:43.985410+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.source_locator

Source artifact SHA-256: c4ad23a62ab161a464fe789e5dd167cf2bfe9f43a91a9c3fb1261b99a5594b0f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-23-2b89723c6dd9 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: segmentnt-supplement-2025-evaluation-segmentnt-3kb-single-task-x14-protein-coding-gene-auprc

areas
genomics
tasks
protein coding gene: per-nucleotide annotation (auPRC)
origin
author_reported
protocol
Test chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons.
comparison
protocol id: segmentnt-supplement-2025-task-protein-coding-gene-auprc; metric implementation: Area under precision-recall curve
missing metadata
checkpoint revision: unreported; seeds: unreported; budget: unreported; split manifest: unextracted
source locator
Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 14; model SegmentNT-3kb-single-task (x14); column protein coding gene
same paper experiment set
segmentnt-2025-human-genome-14-elements
adaptation
Task-specific supervised segmentation training; source-specific backbone and input length retained.
evidence overlap
Tables 2 and 3 report different metrics over the same paper experiment set. They are not independent reproductions or replications.
published score reproduction
false
suite complete
false
evaluation group id
segmentnt-supplement-2025-method-segmentnt-3kb-single-task-x14-segmentnt-supplement-2025-dataset-human-genome-protein-coding-gene-test-chromosomes-20-and-21-evaluation-setup
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