Method

BLOSUM62

Sequence-similarity baseline, with no learned fitness model.

Overview

Sequence-similarity baseline, with no learned fitness model.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

Release 2026-09-17-134cd1815de8 · 4 evaluations · 4 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.

Evaluation setupMetricEvidence origin

Results grouped by the exact reported evaluation
Metric and finding	Coverage and uncertainty	Evidence
BLOSUM62 on FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest split Method: BLOSUM62Task: FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest splitDataset subset: FLIP GB1, 1-vs-rest split (FLIP split) Trained on the split's training set with ten percent held out for validation, scored on its test set. Author-reported evaluation · Evaluation metadata: source checked
0.15 spearman Unit: correlation · Direction: higher	Uncertainty: Not reported Scored: Not reported · Eligible: Not reported	source checkedflip primary benchmark evidence · Table 4, row(BLOSUM62), column(1-vs-rest) Source checking is not independent reproduction.
BLOSUM62 on FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split Method: BLOSUM62Task: FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest splitDataset subset: FLIP GB1, 2-vs-rest split (FLIP split) Trained on the split's training set with ten percent held out for validation, scored on its test set. Author-reported evaluation · Evaluation metadata: source checked
0.14 spearman Unit: correlation · Direction: higher	Uncertainty: Not reported Scored: Not reported · Eligible: Not reported	source checkedflip primary benchmark evidence · Table 4, row(BLOSUM62), column(2-vs-rest) Source checking is not independent reproduction.
BLOSUM62 on FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest split Method: BLOSUM62Task: FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest splitDataset subset: FLIP GB1, 3-vs-rest split (FLIP split) Trained on the split's training set with ten percent held out for validation, scored on its test set. Author-reported evaluation · Evaluation metadata: source checked
0.01 spearman Unit: correlation · Direction: higher	Uncertainty: Not reported Scored: Not reported · Eligible: Not reported	source checkedflip primary benchmark evidence · Table 4, row(BLOSUM62), column(3-vs-rest) Source checking is not independent reproduction.
BLOSUM62 on FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high split Method: BLOSUM62Task: FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high splitDataset subset: FLIP GB1, low-vs-high split (FLIP split) Trained on the split's training set with ten percent held out for validation, scored on its test set. Author-reported evaluation · Evaluation metadata: source checked
-0.13 spearman Unit: correlation · Direction: higher	Uncertainty: Not reported Scored: Not reported · Eligible: Not reported	source checkedflip primary benchmark evidence · Table 4, row(BLOSUM62), column(low-vs-high) Source checking is not independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

0 evidence rows matching the loaded filters