Strengths and considerations
No source-reviewed explanatory claims are recorded here yet.
model · method
Enformer (human fine-tuned) (paper Table 3)
Enformer (human fine-tuned) (paper Table 3). A comparator reported by the AlphaGenome authors; protocol pages specify the dataset and adaptation.
AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track PredictionsAt a glance
Explanatory profile: limited source coverage · Automated source review, 2026-09-17. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.
| Property | Description and evidence |
|---|---|
| Reported method | Enformer (human fine-tuned)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions |
| Exact checkpoint | Not established by the summary table; inspect the protocol and original implementation. · Needs further source reviewAlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions |
| Model type | Not extracted or verified for this record. |
| Inputs | Not extracted or verified for this record. |
| Outputs | Not extracted or verified for this record. |
| Parameters | Not extracted or verified for this record. |
| Training data | Not extracted or verified for this record. |
| Context limits | Not extracted or verified for this record. |
| Access | Not extracted or verified for this record. |
| Code licence | Not extracted or verified for this record. |
| Weights licence | Not extracted or verified for this record. |
How it works
How this comparator was evaluated
The source table identifies Enformer (human fine-tuned). Compare signals in aligned Enformer target bins with the dedicated head and the corresponding Enformer version.
AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track PredictionsBenchmarks and results
Release 2026-09-17-a757f4af4277 · 5 evaluations · 5 metric rows. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| Enformer (human fine-tuned) (paper Table 3): histone ChIP-seq track prediction at 128 bp Model: Enformer (human fine-tuned) (paper Table 3) · Benchmark: histone ChIP-seq track prediction at 128 bp (AlphaGenome paper) · Dataset: histone ChIP-seq track prediction at 128 bp: evaluated data subset Compare signals in aligned Enformer target bins with the dedicated head and the corresponding Enformer version. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.697 pearsonr Unit: correlation · Direction: higher Aggregation: Pearson correlation summarized over the relevant modality tracks. | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J35 Source checking is not independent reproduction. |
| Enformer (human fine-tuned) (paper Table 3): ATAC track prediction at 128 bp Model: Enformer (human fine-tuned) (paper Table 3) · Benchmark: ATAC track prediction at 128 bp (AlphaGenome paper) · Dataset: ATAC track prediction at 128 bp: evaluated data subset Compare signals in aligned Enformer target bins with the dedicated head and the corresponding Enformer version. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.706 pearsonr Unit: correlation · Direction: higher Aggregation: Pearson correlation summarized over the relevant modality tracks. | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J32 Source checking is not independent reproduction. |
| Enformer (human fine-tuned) (paper Table 3): TF ChIP-seq track prediction at 128 bp Model: Enformer (human fine-tuned) (paper Table 3) · Benchmark: TF ChIP-seq track prediction at 128 bp (AlphaGenome paper) · Dataset: TF ChIP-seq track prediction at 128 bp: evaluated data subset Compare signals in aligned Enformer target bins with the dedicated head and the corresponding Enformer version. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.572 pearsonr Unit: correlation · Direction: higher Aggregation: Pearson correlation summarized over the relevant modality tracks. | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J38 Source checking is not independent reproduction. |
| Enformer (human fine-tuned) (paper Table 3): CAGE track prediction at 128 bp Model: Enformer (human fine-tuned) (paper Table 3) · Benchmark: CAGE track prediction at 128 bp (AlphaGenome paper) · Dataset: CAGE track prediction at 128 bp: evaluated data subset Compare signals in aligned Enformer target bins with the dedicated head and the corresponding Enformer version. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.712 pearsonr Unit: correlation · Direction: higher Aggregation: Pearson correlation summarized over the relevant modality tracks. | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J19 Source checking is not independent reproduction. |
| Enformer (human fine-tuned) (paper Table 3): DNase track prediction at 128 bp Model: Enformer (human fine-tuned) (paper Table 3) · Benchmark: DNase track prediction at 128 bp (AlphaGenome paper) · Dataset: DNase track prediction at 128 bp: evaluated data subset Compare signals in aligned Enformer target bins with the dedicated head and the corresponding Enformer version. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.852 pearsonr Unit: correlation · Direction: higher Aggregation: Pearson correlation summarized over the relevant modality tracks. | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J26 Source checking is not independent reproduction. |
Strengths and limitations
Limitations and conditions
- A table label does not establish identity with any other catalogue configuration bearing the same name.AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions
Profile review details
Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.
Stable record: alphagenome-2026-comparator-6b076b15946a5f8aEvidence table
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
15 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported method Enformer (human fine-tuned) Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Reported method Enformer (human fine-tuned) Individual claims | AlphaGenome Nature 2026 supplementary methods 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplement to Nature version of record, 28 January 2026; content hash pinned | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact publisher PDF bytes Format: original_pdf |
| Reported method Enformer (human fine-tuned) Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature version of record, 28 January 2026 | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx |
| Exact checkpoint Not established by the summary table; inspect the protocol and original implementation. Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | unextracted automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Exact checkpoint Not established by the summary table; inspect the protocol and original implementation. Individual claims | AlphaGenome Nature 2026 supplementary methods 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplement to Nature version of record, 28 January 2026; content hash pinned | unextracted automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact publisher PDF bytes Format: original_pdf |
| Exact checkpoint Not established by the summary table; inspect the protocol and original implementation. Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature version of record, 28 January 2026 | unextracted automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx |
| Limitation A table label does not establish identity with any other catalogue configuration bearing the same name. Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Limitation A table label does not establish identity with any other catalogue configuration bearing the same name. Individual claims | AlphaGenome Nature 2026 supplementary methods 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplement to Nature version of record, 28 January 2026; content hash pinned | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact publisher PDF bytes Format: original_pdf |
| Limitation A table label does not establish identity with any other catalogue configuration bearing the same name. Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature version of record, 28 January 2026 | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx |
| How this comparator was evaluated The source table identifies Enformer (human fine-tuned). Compare signals in aligned Enformer target bins with the dedicated head and the corresponding Enformer version. Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A19:N19; Supplementary Methods p.24, Benchmarking Against Enformer Track Predictions Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
Sources and history
Release 2026-09-17-a757f4af4277 · Record review: needs review
- AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
- AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
- alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied
Technical metadata and extraction receipts
Stable ID: alphagenome-2026-comparator-6b076b15946a5f8a
- areas
- dna-genomes
- entity level
- method
- configuration type
- reported_configuration
- version
- Enformer (human fine-tuned) (paper Table 3)
Related records
- model: Enformer (human fine-tuned) (paper Table 3): histone ChIP-seq track prediction at 128 bp
- model: Enformer (human fine-tuned) (paper Table 3): CAGE track prediction at 128 bp
- model: Enformer (human fine-tuned) (paper Table 3): ATAC track prediction at 128 bp
- model: Enformer (human fine-tuned) (paper Table 3): DNase track prediction at 128 bp
- model: Enformer (human fine-tuned) (paper Table 3): TF ChIP-seq track prediction at 128 bp