Strengths supported by sources
- Supports unconditional generation and constrained protein-design problems.RosettaCommons/RFdiffusion official source · README.md: What is RFdiffusion? and supported design challenges
model · family
RFdiffusion
RFdiffusion generates protein structures with optional conditioning such as motifs or target information.
At a glance
Explanatory profile: source reviewed · Automated source review, 2026-09-16. This does not change the review status of its results.
| Property | Description and evidence |
|---|---|
| Output | Generated protein structuresRosettaCommons/RFdiffusion official source · README.md: What is RFdiffusion? and supported design challenges |
| Model type | Not extracted or verified for this record. |
| Known versions | Not extracted or verified for this record. |
| Training data | Not extracted or verified for this record. |
| Context limits | Not extracted or verified for this record. |
| Access | Not extracted or verified for this record. |
| Code licence | Not extracted or verified for this record. |
| Weights licence | Not extracted or verified for this record. |
How it works
Schematic of the documented input, computation and output; not an executable configuration.
Read the diagram as text
- Design constraints
- Structure diffusion
- Generated backbone
- Separate sequence design
- Experimental evaluation
A diffusion-based structure-generation workflow samples designs subject to the selected conditioning. Sequence design and experimental testing are subsequent steps rather than guaranteed properties of the generated backbone.
RosettaCommons/RFdiffusion official source · README.md: What is RFdiffusion? and supported design challengesBenchmarks and results
Release 2026-09-16-d74d282221a9 · 0 evaluations · 0 metric rows. Different protocols are not a single leaderboard.
No evaluations linked in this release.
Strengths and limitations
Limitations and conditions
- A generated structure is a candidate design, not evidence of an experimentally functional binder.RosettaCommons/RFdiffusion official source · README.md: What is RFdiffusion? and supported design challenges
Profile review details
Primary project documentation or paper inspected for the explanatory claims and cited locations. Reviewed coverage concerns this narrative, not complete metadata, independent reproduction or a performance ranking.
Stable record: discovery-model-rfdiffusionApplicable tests and references
Applicability is distinct from a completed evaluation.
- ProteinBench · Proposed association
Sources and history
Release 2026-09-16-d74d282221a9 · Record review: discovered
- RosettaCommons/RFdiffusion official source · Original source · 86507b6538f51fce57b5a72477165f03999ed7ae
Technical metadata and extraction receipts
Stable ID: discovery-model-rfdiffusion
- areas
- protein-structure
- access
- official_source_linked
- benchmark applicability
- candidate; not evidence of a reported evaluation
- candidate benchmark ids
- discovery-benchmark-proteinbench
- entity level
- family
- missing metadata
- checkpoint: unextracted; code licence: unextracted; parameters: unextracted; training cutoff: unextracted; training data: unextracted; version: unextracted; weights licence: unextracted
- reported name
- RFdiffusion
- version
- Not reported
Related records
- applicable to: ProteinBench