Model type
Study-specific predictive method; this record is the paper-specific evaluated configuration.
Pipeline
CATHe2 + ProstT5
CATHe2 classifies protein domains into CATH superfamilies using ProstT5 representations of sequence and structure.
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Introduction (paragraph 5)How it worksEvaluated procedure (conceptual)
Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3)At a glance
Biological inputs
Protein-domain amino-acid sequences and 3Di structural-alphabet sequences
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Introduction (paragraph 2)Outputs
CATH superfamily assignments
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Discussion/Critical analysis of the study (paragraph 1)limited source coverage · Automated source review, 2026-09-16. All specifications and missing details
Evaluations and results
Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| CATHe2 + ProstT5: CATH superfamily annotation amino-acid and structural alphabet embedding classifier Author-reported evaluation · Evaluation metadata: needs review | ||
| 82.3% F1 Unit: percent · Direction: unknown | Uncertainty: ± 1.3 percentage points Scored: Not reported · Eligible: Not reported | source checkedCATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Table 3, ProstT5 full row, F1 score column Source checking is not independent reproduction. |
How it works
How the evaluated method works
A feed-forward classifier consumes ProstT5 amino-acid embeddings and 3Di structural-alphabet embeddings. This record is the complete CATHe2 classifier with the full ProstT5 feature extractor.
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3)What was evaluated
The linked evaluation record identifies CATHe2 + ProstT5: CATH superfamily annotation. Its dataset, split, adaptation and evidence origin remain attached to the reported results.
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-b2-cathe2-2025Strengths and limitations
Strengths and considerations
- Combines sequence and structural representations and evaluates remote homology under a stringent identity filter.
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Materials and methods/Data and datasets (paragraph 2); Introduction (paragraph 3)
Limitations and conditions
- The evaluated label space covers selected represented CATH superfamilies; it does not establish classification of every rare or unseen superfamily.
Sources
CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Materials and methods/Data and datasets (paragraph 3); Materials and methods/Data and datasets (paragraph 2)
Profile review details
Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.
Stable record: reported-model-49bc768f46b366Specifications
Inputs, training, access and other details
Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.
| Property | Description and evidence |
|---|---|
| Model type | Study-specific predictive method; this record is the paper-specific evaluated configuration.SourcesCATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) |
| Architecture / procedure | A feed-forward classifier consumes ProstT5 amino-acid embeddings and 3Di structural-alphabet embeddings. This record is the complete CATHe2 classifier with the full ProstT5 feature extractor.SourcesCATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) |
| Biological inputs | Protein-domain amino-acid sequences and 3Di structural-alphabet sequencesSourcesCATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Introduction (paragraph 2) |
| Outputs | CATH superfamily assignmentsSourcesCATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Abstract (paragraph 1); Discussion/Critical analysis of the study (paragraph 1) |
| Parameters | An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sourcesSources (2)CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets; Mouret-Orfeu/CATHe2 README.md · Materials and methods/Data and datasets; Materials and methods/Additional experiments; Materials and methods/3Di processing; Materials and methods/Models; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision |
| Known versions / configuration | full ProstT5SourcesCATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Table bpaf080-T3 (paragraph 1); Results/CATHe2 models performance (paragraph 1) |
| Training data / fitting | CATH-Gene3D-derived domains; the larger training set has 1,039,135 domains, with less than 20% sequence identity between and within train, validation and test partitions.SourcesCATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Materials and methods/Data and datasets (paragraph 2); Materials and methods/Data and datasets (paragraph 1) |
| Context limits | A maximum input/context length for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sourcesSources (2)CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets; Mouret-Orfeu/CATHe2 README.md · Materials and methods/Data and datasets; Materials and methods/Additional experiments; Materials and methods/3Di processing; Materials and methods/Models; inspected for explicit maximum input length (dataset lengths and family-wide limits are not substituted); README.md at pinned repository revision |
| Access | Official study implementation and usage documentation: https://github.com/Mouret-Orfeu/CATHe2/blob/cdaf5f4c8d9dfda86f78fd0efc83ab22a30e9ffd/README.md. This pinned documentation revision is not automatically the evaluated weight revision.SourcesMouret-Orfeu/CATHe2 README.md · README.md; installation, model download and usage instructions |
| Code licence | MIT (study repository code at the cited revision; this does not establish every dependency or historical checkpoint licence).SourcesMouret-Orfeu/CATHe2 LICENSE · LICENSE; complete licence text |
| Weights licence | The inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately. · Not reported in inspected sourcesSourcesMouret-Orfeu/CATHe2 README.md · README.md; checkpoint/access documentation and licence scope |
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
21 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Diagram caption Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings. Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) Version: journal full text in PMC | source checked automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Diagram steps ["Protein-domain amino-acid sequences and 3Di structural-alphabet sequences","CATHe2 + ProstT5","CATH superfamily assignments"] Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) Version: journal full text in PMC | source checked automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Diagram title Evaluated procedure (conceptual) Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) Version: journal full text in PMC | source checked automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Model type Study-specific predictive method; this record is the paper-specific evaluated configuration. Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) Version: journal full text in PMC | source checked automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Architecture / procedure A feed-forward classifier consumes ProstT5 amino-acid embeddings and 3Di structural-alphabet embeddings. This record is the complete CATHe2 classifier with the full ProstT5 feature extractor. Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) Version: journal full text in PMC | source checked automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Weights licence The inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately. Individual claims | Mouret-Orfeu/CATHe2 README.md README.md; checkpoint/access documentation and licence scope Version: cdaf5f4c8d9dfda86f78fd0efc83ab22a30e9ffd | unreported automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Biological inputs Protein-domain amino-acid sequences and 3Di structural-alphabet sequences Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Abstract (paragraph 1); Introduction (paragraph 2) Version: journal full text in PMC | source checked automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Outputs CATH superfamily assignments Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Abstract (paragraph 1); Discussion/Critical analysis of the study (paragraph 1) Version: journal full text in PMC | source checked automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Parameters An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources. Individual claims | CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets Materials and methods/Data and datasets; Materials and methods/Additional experiments; Materials and methods/3Di processing; Materials and methods/Models; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: journal full text in PMC | unreported automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Parameters An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources. Individual claims | Mouret-Orfeu/CATHe2 README.md Materials and methods/Data and datasets; Materials and methods/Additional experiments; Materials and methods/3Di processing; Materials and methods/Models; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cdaf5f4c8d9dfda86f78fd0efc83ab22a30e9ffd | unreported automated source review · 2026-09-16 Audit detailsPrimary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
Release 2026-09-17-d277315f7d76 · Record review: needs review
3 source records and release history
- CATHe2: Enhanced CATH superfamily detection using ProstT5 and structural alphabets · Original source · journal full text in PMC
- Mouret-Orfeu/CATHe2 README.md · Original source · cdaf5f4c8d9dfda86f78fd0efc83ab22a30e9ffd
- Mouret-Orfeu/CATHe2 LICENSE · Original source · cdaf5f4c8d9dfda86f78fd0efc83ab22a30e9ffd
Technical metadata and extraction receipts
Stable ID: reported-model-49bc768f46b366
- areas
- proteins-complexes
- entity level
- method
- version
- full ProstT5
- reported name
- CATHe2 + ProstT5
- historical missing metadata
- checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
- metadata review scope
- historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
- legacy kinds
- model
- entity classification
- review date: 2026-09-17; rationale: This record identifies a composed analysis workflow with separately identifiable upstream models, representations or tools and a downstream prediction/scoring procedure. Results belong to that complete composition rather than to an upstream model alone.; source ids: cathe2-2025; source locator: Abstract (paragraph 1); Results/CATHe2 models performance (paragraph 3) | Abstract (paragraph 1); Introduction (paragraph 5); ambiguities: This is the paper-specific pipeline identity; unspecified component checkpoints or implementation versions are not inferred from its name.