result · source checked

0.51 all_tissues_auprc

AlphaGenome distilled all-fold student: Author MFASS splice-disruption prediction, all tissues auprc

Tested model: AlphaGenome distilled all-fold student
Model family: AlphaGenome
Task or benchmark: Author MFASS splice-disruption prediction (AlphaGenome paper)
Dataset: Author MFASS splice-disruption prediction: evaluated data subset
Procedure: Use the MFASS-specific donor/acceptor and junction scoring procedure, sum splicing components, then average across tissues. Compare with the source’s exon-inclusion disruption label.
Evaluation: AlphaGenome distilled all-fold student: Author MFASS splice-disruption prediction
Evidence: Author-reported evaluation · source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 4 Variant performan'!M8

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Evaluation results

Release 2026-09-17-a757f4af4277 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Evaluated configurationMetricEvidence origin

Results grouped by the exact reported evaluation
Metric and finding	Coverage and uncertainty	Evidence
AlphaGenome distilled all-fold student: Author MFASS splice-disruption prediction Model: AlphaGenome distilled all-fold student · Benchmark: Author MFASS splice-disruption prediction (AlphaGenome paper) · Dataset: Author MFASS splice-disruption prediction: evaluated data subset Use the MFASS-specific donor/acceptor and junction scoring procedure, sum splicing components, then average across tissues. Compare with the source’s exon-inclusion disruption label. Author-reported evaluation · Evaluation metadata: needs review
0.51 all_tissues_auprc Unit: dimensionless · Direction: higher Aggregation: auPRC for the splice-disrupting label defined by the MFASS exon-inclusion threshold.	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 4 Variant performan'!M8 Source checking is not independent reproduction.

Evidence table

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-a757f4af4277
Property and statement	Original source and location	Review and provenance
Reported result 0.51 Individual claims	AlphaGenome Nature 2026 supplementary comparison tables Original source ↗ 'Suppl Table 4 Variant performan'!M8 Version: Nature version of record, 28 January 2026 Retrieved: 2026-09-17T06:31:06.887921+00:00	source checked OOXML extraction and separate automated primary-source review · 2026-09-17 author reported Audit details Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun. Field: `attributes.printed_value` Source artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx Inspected artifact Extraction artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Extraction artifact

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Sources and history

Release 2026-09-17-a757f4af4277 · Record review: source checked

AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied

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Technical metadata and extraction receipts

Stable ID: alphagenome-2026-result-2d42e8f31598adca

areas: dna-genomes
printed value: 0.51
printed value basis: Workbook number format 0.00
numeric value: 0.51200000000000001
raw xml value: 0.51200000000000001
workbook number format: 0.00
metric: all_tissues_auprc
metric direction: higher
unit: dimensionless
aggregation: auPRC for the splice-disrupting label defined by the MFASS exon-inclusion threshold.
uncertainty: Not reported
scored count: Not reported
eligible count: Not reported
source cells: 'Suppl Table 4 Variant performan'!M8
source locator: 'Suppl Table 4 Variant performan'!M8
review: method: OOXML extraction and separate automated primary-source review; date: 2026-09-17; artifact sha256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154; retrieval url: https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41586-025-10014-0/MediaObjects/41586_2025_10014_MOESM3_ESM.xlsx; note: Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun.
missing metadata: uncertainty: unreported; scored count: unextracted; eligible count: unextracted; seeds: unreported
source warnings: None recorded

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evaluation: AlphaGenome distilled all-fold student: Author MFASS splice-disruption prediction

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