0.394 AUC
ESM-2 8M masked-marginal scoring: AUC
- Tested configuration
- ESM-2 8M masked-marginal scoring (ProteinGym v1.3 AMFR substitution assay)
- Protocol
- ProteinGym v1.3 AMFR substitution assay
- Dataset subset
- ProteinGym v1.3 AMFR substitution assay full assay
- Related family profiles
- ESM-2
- Procedure
- ProteinGym v1.3 AMFR substitution assay
- Evaluation
- ESM-2 8M masked-marginal scoring on ProteinGym v1.3 AMFR substitution assay
- Coverage
- 2972/2972
- Uncertainty
- Not reported
- Evidence
- Rewire evaluation · source checkedESM-2 8M masked-marginal scoring: local execution report (20 September 2026); ESM-2 8M masked-marginal scoring: automated execution audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.AUC
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.
Reproduction
- Split
- Full assay; no train/test split
- Adaptation
- zero-shot masked marginals
- Scoring implementation
- fcc5ab65e6753cf29aabbdae231cbb5cdf72a3dd40ba8f109802c33223b33536
Generate and evaluate predictions
This committed script regenerates the selected AMFR assay using the recorded checkpoint and masked-marginal scorer. It is not the complete ProteinGym track or a reproduction of a paper score.
ProteinGym v1.3 AMFR substitution assay: reproduction instructions · Reproduce sectionReproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
2 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 0.394 Individual claims | ESM-2 8M masked-marginal scoring: automated execution audit protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.AUC Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: ca73fa47136d182f2d4ddb083d084712198fc0e2 | source checked automated execution evidence review · 2026-09-20T20:54:03Z rewire run Audit detailsNumerical transcription and coverage checked against execution evidence; not human review or reproduction of a published model score. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Reported result 0.394 Individual claims | ESM-2 8M masked-marginal scoring: local execution report (20 September 2026) protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.AUC Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: ca73fa47136d182f2d4ddb083d084712198fc0e2 | source checked automated execution evidence review · 2026-09-20T20:54:03Z rewire run Audit detailsNumerical transcription and coverage checked against execution evidence; not human review or reproduction of a published model score. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
View linked audit checks and correction history
Release 2026-09-22-f58a0f1d267f · Record review: source checked
3 source records and release history
- ESM-2 8M masked-marginal scoring: local execution report (20 September 2026) · Original source · ca73fa47136d182f2d4ddb083d084712198fc0e2
- ESM-2 8M masked-marginal scoring: automated execution audit · Original source · ca73fa47136d182f2d4ddb083d084712198fc0e2
- ProteinGym v1.3 AMFR substitution assay: reproduction instructions · Original source · ca73fa47136d182f2d4ddb083d084712198fc0e2
Technical metadata and extraction receipts
Stable ID: rewire-local-20260920-result-proteingym-esm2-auc
- areas
- proteins-complexes
- printed value
- 0.394
- numeric value
- 0.394
- metric
- AUC
- metric key
- AUC
- metric direction
- higher
- unit
- dimensionless
- uncertainty
- Not reported
- eligible count
- 2972
- scored count
- 2972
- missing count
- 0
- coverage
- 2972/2972
- source locator
- protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.AUC
- undefined reason
- Not reported
- review
- method: automated_execution_evidence_review; reviewer: Automated report and saved-prediction verification; reviewed at: 2026-09-20T20:54:03Z; notes: Numerical transcription and coverage checked against execution evidence; not human review or reproduction of a published model score.
- missing metadata
- uncertainty: Not estimated; one complete selected evaluation.