rewire.it
Task

Enhancer / MPRA effects

Enhancer-effect evaluation asks whether sequence-based predictions track measured changes in regulatory activity.

Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

0 evaluations · 0 metric rows

At a glance

Inputs, training, access and other details

Explanatory profile: source reviewed · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Data, procedure and scoring
PropertyDescription and evidence
Entity typeTask guide; concrete protocol identities remain separate.
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
DatasetsNo single dataset is fixed by this guide. Select a linked protocol and its versioned data release. · Not applicable
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
OrganismsNo shared organism population is defined at this guide level. Record it for each selected dataset. · Not applicable
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
AssaysNo single measurement assay is fixed by this guide; the endpoint and assay belong to the selected protocol. · Not applicable
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
SplitsNo executable split is attached to this task identity. Use the selected protocol’s split manifest. · Not applicable
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
Allowed inputsRegulatory DNA or matched alleles and a specified experimental activity endpoint, with genome assembly and window placement recorded.
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
AdaptationNo common fitting regime is imposed here. Keep pretrained, frozen, probed, fine-tuned and conventional methods distinct where applicable. · Not applicable
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
MetricsUse the metric attached to the concrete task: regulatory-element classification and quantitative effect prediction require different scoring.
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
BaselinesDART-Eval includes supervised models trained from scratch, including ChromBPNet-related baselines, alongside language-model evaluation modes.
Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

How it works

How it worksConceptual evaluation workflow
Conceptual evaluation workflow1. Choose assay endpoint and split. Then: 2. Define DNA windows and alleles. Then: 3. Apply declared prediction configuration. Then: 4. Compare scores with measured effectsConceptual evaluation workflow1. Choose assay endpoint and split. Then: 2. Define DNA windows and alleles. Then: 3. Apply declared prediction configuration. Then: 4. Compare scores with measured effectsConceptual evaluation workflow1. Choose assay endpoint and split. Then: 2. Define DNA windows and alleles. Then: 3. Apply declared prediction configuration. Then: 4. Compare scores with measured effects

Conceptual task guide. Dataset preparation, parameters and scoring must come from a separately identified protocol.

Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
Choosing an evaluation

Separate detection of regulatory DNA from prediction of the effect of a sequence change. A reporter assay and endogenous chromatin-accessibility assay are different endpoints. DART-Eval provides concrete regulatory prediction tasks and comparisons across frozen, probed and fine-tuned models. Use its exact task and data release rather than treating every enhancer test as equivalent.

Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines
Task scope

This is a task guide, not a single versioned benchmark protocol. The connected resources provide examples or concrete procedures. A candidate method or proposed control is not evidence that an evaluation has been completed.

Sources (2)kundajelab/DART-Eval official source; DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Tested entities and results

Release 2026-09-17-d277315f7d76 · 0 evaluations · 0 metric rows. Different protocols are not a single leaderboard.

No evaluations linked in this release.

Papers and result coverage

Last literature check: 2026-09-17. Primary-source discovery and table/protocol screening; source checked is not independently reproduced. Raw acquisitions not automatically numerical publication approval.

What is still missing

  • Regulatory sequence detection, TF motifs, cell-type activity and variant effects are distinct protocols. Enhancer broad-task record must link concrete tasks, not inherit every DART result. Existing DART observations require source-cell identity reuse.
Search and extraction details

broad task requires concrete protocol links

Searches

  • DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA primary paper benchmark results

Evidence locations

  • arXiv v1 main benchmark procedures and results tables

Strengths and limitations

Profile review details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Stable record: catalog-task-enhancer-effects

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

34 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual task guide. Dataset preparation, parameters and scoring must come from a separately identified protocol.

Individual claims
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NeurIPS 2024 Datasets and Benchmarks Track proceedings
Retrieved: 2026-09-16T10:38:57.558203+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: e5aee5b1f7cc6fd961b1d2a131d02cf243b79e091d5e418fbabee7fde9b39b22

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram caption

Conceptual task guide. Dataset preparation, parameters and scoring must come from a separately identified protocol.

Individual claims
kundajelab/DART-Eval official source

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: af2a86d666c35304257c2fa7e15180e1fbcabb01
Retrieved: 2026-09-16T10:30:21.153480+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: d21ee86b56c9b794f5b58f3c39c3e27c51d027a3b280d848457abf53f521f052

Hash scope: Hash scope not separately documented; inspect source record

Diagram steps

["Choose assay endpoint and split","Define DNA windows and alleles","Apply declared prediction configuration","Compare scores with measured effects"]

Individual claims
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NeurIPS 2024 Datasets and Benchmarks Track proceedings
Retrieved: 2026-09-16T10:38:57.558203+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: e5aee5b1f7cc6fd961b1d2a131d02cf243b79e091d5e418fbabee7fde9b39b22

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Choose assay endpoint and split","Define DNA windows and alleles","Apply declared prediction configuration","Compare scores with measured effects"]

Individual claims
kundajelab/DART-Eval official source

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: af2a86d666c35304257c2fa7e15180e1fbcabb01
Retrieved: 2026-09-16T10:30:21.153480+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: d21ee86b56c9b794f5b58f3c39c3e27c51d027a3b280d848457abf53f521f052

Hash scope: Hash scope not separately documented; inspect source record

Diagram title

Conceptual evaluation workflow

Individual claims
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NeurIPS 2024 Datasets and Benchmarks Track proceedings
Retrieved: 2026-09-16T10:38:57.558203+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.diagram.title

Source artifact SHA-256: e5aee5b1f7cc6fd961b1d2a131d02cf243b79e091d5e418fbabee7fde9b39b22

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Conceptual evaluation workflow

Individual claims
kundajelab/DART-Eval official source

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: af2a86d666c35304257c2fa7e15180e1fbcabb01
Retrieved: 2026-09-16T10:30:21.153480+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.diagram.title

Source artifact SHA-256: d21ee86b56c9b794f5b58f3c39c3e27c51d027a3b280d848457abf53f521f052

Hash scope: Hash scope not separately documented; inspect source record

Entity type

Task guide; concrete protocol identities remain separate.

Individual claims
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NeurIPS 2024 Datasets and Benchmarks Track proceedings
Retrieved: 2026-09-16T10:38:57.558203+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: e5aee5b1f7cc6fd961b1d2a131d02cf243b79e091d5e418fbabee7fde9b39b22

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Entity type

Task guide; concrete protocol identities remain separate.

Individual claims
kundajelab/DART-Eval official source

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: af2a86d666c35304257c2fa7e15180e1fbcabb01
Retrieved: 2026-09-16T10:30:21.153480+00:00

source checked

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: d21ee86b56c9b794f5b58f3c39c3e27c51d027a3b280d848457abf53f521f052

Hash scope: Hash scope not separately documented; inspect source record

Datasets

No single dataset is fixed by this guide. Select a linked protocol and its versioned data release.

Individual claims
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NeurIPS 2024 Datasets and Benchmarks Track proceedings
Retrieved: 2026-09-16T10:38:57.558203+00:00

inapplicable

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: e5aee5b1f7cc6fd961b1d2a131d02cf243b79e091d5e418fbabee7fde9b39b22

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Datasets

No single dataset is fixed by this guide. Select a linked protocol and its versioned data release.

Individual claims
kundajelab/DART-Eval official source

Original source ↗

DART-Eval README Task 5; paper evaluation tasks and ab initio baselines

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: af2a86d666c35304257c2fa7e15180e1fbcabb01
Retrieved: 2026-09-16T10:30:21.153480+00:00

inapplicable

automated source review · 2026-09-16

Audit details

Reviewed named primary documentation and existing protocol records. Editorial task scope is distinguished from source-reported procedures. No model execution or new numerical result; a reviewed guide is not a complete runnable protocol.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: d21ee86b56c9b794f5b58f3c39c3e27c51d027a3b280d848457abf53f521f052

Hash scope: Hash scope not separately documented; inspect source record

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: discovered

7 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: catalog-task-enhancer-effects

areas
dna-genomes
entity level
task
version
Not reported
task
Enhancer / MPRA effects
scope note
Predict measured activity changes from regulatory sequence variants.
benchmark research
review date: 2026-09-17; status: broad_task_requires_concrete_protocol_links; primary sources: evidence-expansion-p2-evidence-discovery-final-dart-4194b137ba55; inspected locators: arXiv v1 main benchmark procedures and results tables; searched queries: DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA primary paper benchmark results; gaps: Regulatory sequence detection, TF motifs, cell-type activity and variant effects are distinct protocols. Enhancer broad-task record must link concrete tasks, not inherit every DART result. Existing DART observations require source-cell identity reuse.; claim scope: Primary-source discovery and table/protocol screening; source checked is not independently reproduced. Raw acquisitions not automatically numerical publication approval.
historical missing metadata
protocol version: not_yet_extracted
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
benchmark
entity classification
review date: 2026-09-17; rationale: This record identifies the biological prediction question or a suite-specific task, rather than a uniquely fixed evaluated procedure. Preserve its task identity and leave split, model adaptation and scoring details on linked protocols/evaluations.; source ids: src-discovery-kundajelab-dart-eval; dart-eval-regulatory-2024; source locator: DART-Eval README Task 5; paper evaluation tasks and ab initio baselines; ambiguities: None recorded
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