rewire.it
Task

Multi-species prokaryotic promoter detection

Multi-species promoter classification uses curated positives and genomic-background negatives.

SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

2 evaluations · 2 metric rows

At a glance

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Data, procedure and scoring
PropertyDescription and evidence
DatasetsPromoter annotations from PPD and species-matched negative sequence collections.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
SplitsFive-fold cross-validation is used for fitting and an independent collection for comparison.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
MetricsSensitivity, specificity, accuracy, MCC and ROC-AUC.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
BaselinesGeneric classifiers are random forest, XGBoost, logistic regression and LSTM, trained with five-fold cross-validation. Tool comparisons use Prompt, PromoterLCNN and iPro-WAEL on the same species-specific independent tests; a separate repeat uses their official five-fold training protocols.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Results: Tables 1–2; comparison with baseline classifiers and existing tools; cached paragraphs 29–37
Leakage controlsThe source describes CD-HIT redundancy filtering for both classes.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
UncertaintyThe cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim. · Not reported in inspected sources
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
Entity typePaper-specific computational evaluation protocol.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
OrganismsMultiple prokaryotic species in PPD.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
AssaysPromoter annotations and species-matched negatives.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
Allowed inputsDNA sequence windows.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
AdaptationSupervised promoter classification with cross-validation and an independent collection.
SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

How it works

How it worksComputational evaluation flow
Computational evaluation flow1. Input: DNA sequence windows.. Then: 2. Evaluation: Supervised promoter classification with cross-validation and an independent collection.. Then: 3. Readout: Sensitivity, specificity, accuracy, MCC and ROC-AUC.Computational evaluation flow1. Input: DNA sequence windows.. Then: 2. Evaluation: Supervised promoter classification with cross-validation and an independent collection.. Then: 3. Readout: Sensitivity, specificity, accuracy, MCC and ROC-AUC.Computational evaluation flow1. Input: DNA sequence windows.. Then: 2. Evaluation: Supervised promoter classification with cross-validation and an independent collection.. Then: 3. Readout: Sensitivity, specificity, accuracy, MCC and ROC-AUC.

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72
Evaluation methodology

Promoter annotations from PPD and species-matched negative sequence collections. Five-fold cross-validation is used for fitting and an independent collection for comparison. Sensitivity, specificity, accuracy, MCC and ROC-AUC. The source describes CD-HIT redundancy filtering for both classes. The cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim.

SourcesiPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Tested entities and results

Release 2026-09-17-d277315f7d76 · 2 evaluations · 2 metric rows. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
iPro-MP: Multi-species prokaryotic promoter detection

Average over independent testing sets.

Author-reported evaluation · Evaluation metadata: needs review

0.935 Mean AUC

Unit: unitless · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkediPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Table 2, iPro-MP row, AUC column

Source checking is not independent reproduction.

Prompt: Multi-species prokaryotic promoter detection

Average over the same independent testing sets.

Independent external evaluation · Evaluation metadata: needs review

0.835 Mean AUC

Unit: unitless · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkediPro-MP: a BERT-based model to predict multiple prokaryotic promoters · Table 2, Prompt row, AUC column

Source checking is not independent reproduction.

Papers and result coverage

Last literature check: 2026-09-17. Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.

Paper or primary resourceVersionReference
iPro-MP: a BERT-based model to predict multiple prokaryotic promotersversion of recordRead source
DOI: 10.1186/s13059-025-03819-9

What is still missing

  • iPro-MP's first four scores duplicate across Tables 1–2; one result with two source occurrences.
  • Species-averaged accuracy/AUROC/AUPRC/MCC differ from pooled sample scores; retain source aggregation.
  • Runtime is seconds, lower-is-better, and hardware-dependent.
Search and extraction details

primary comparison table screened

Searches

  • "PMC12516880"

Evidence locations

  • Tables 1–3
  • Methods: Data collection and preprocessing; Performance evaluation

Strengths and limitations

Strengths and considerations

No source-reviewed explanatory claims are recorded here yet.

Limitations and conditions

Profile review details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Stable record: reported-task-a1151e386a3d3f

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

17 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Input: DNA sequence windows.","Evaluation: Supervised promoter classification with cross-validation and an independent collection.","Readout: Sensitivity, specificity, accuracy, MCC and ROC-AUC."]

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Computational evaluation flow

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.title

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Datasets

Promoter annotations from PPD and species-matched negative sequence collections.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Splits

Five-fold cross-validation is used for fitting and an independent collection for comparison.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Adaptation

Supervised promoter classification with cross-validation and an independent collection.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Metrics

Sensitivity, specificity, accuracy, MCC and ROC-AUC.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Baselines

Generic classifiers are random forest, XGBoost, logistic regression and LSTM, trained with five-fold cross-validation. Tool comparisons use Prompt, PromoterLCNN and iPro-WAEL on the same species-specific independent tests; a separate repeat uses their official five-fold training protocols.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Results: Tables 1–2; comparison with baseline classifiers and existing tools; cached paragraphs 29–37

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Leakage controls

The source describes CD-HIT redundancy filtering for both classes.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Uncertainty

The cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim.

Individual claims
iPro-MP: a BERT-based model to predict multiple prokaryotic promoters

Original source ↗

Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72

Version: version of record
Retrieved: 2026-09-16T10:33:55.361Z

unreported

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: d21541ee1f7a168da8e4a7c0f0e133c970cbe7bc41118f43a929f08b2fd2afd1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-task-a1151e386a3d3f

areas
microbes-communities
tasks
Multi-species prokaryotic promoter detection
entity level
task
version
Not reported
task
Multi-species prokaryotic promoter detection
scope note
Paper-specific evaluation task; protocol completeness requires further extraction.
benchmark research
review date: 2026-09-17; status: primary_comparison_table_screened; primary sources: expansion-p3-ipromp-2025; inspected locators: Tables 1–3; Methods: Data collection and preprocessing; Performance evaluation; searched queries: "PMC12516880"; gaps: iPro-MP's first four scores duplicate across Tables 1–2; one result with two source occurrences.; Species-averaged accuracy/AUROC/AUPRC/MCC differ from pooled sample scores; retain source aggregation.; Runtime is seconds, lower-is-better, and hardware-dependent.; claim scope: Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.
historical missing metadata
protocol version: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
benchmark
entity classification
review date: 2026-09-17; rationale: This source-scoped record identifies the biological prediction task and holds its paper context. Preserve the existing task identity; exact split, model adaptation and scoring remain in linked evaluations or separate protocol records.; source ids: ipromp-2025; source locator: Methods: Data collection and preprocessing; Performance evaluation; cached text lines 54–56, 69–72; ambiguities: A paper- or suite-specific task may constrain some inputs or metrics; that alone does not make it interchangeable with a complete versioned protocol. No protocol equivalence is inferred.; Some legacy profile Entity type facts use the generic phrase computational evaluation protocol. That boilerplate is not sufficient to establish a single fixed protocol identity or to merge this task with another protocol record.
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