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CAFA

CAFA is a time-based challenge for predicting protein function.

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At a glance

Explanatory profile: source reviewed · Automated source review, 2026-09-16. This does not change the review status of its results.

Data, procedure and scoring
PropertyDescription and evidence
Record typeProspective challengecafa official source · Official CAFA page: The CAFA Challenge, prediction and annotation-growth timeline
InputsProtein sequences and ontology-term predictionscafa official source · Official CAFA page: The CAFA Challenge, prediction and annotation-growth timeline
Outputs and assessmentAgreement with subsequently acquired functional annotationscafa official source · Official CAFA page: The CAFA Challenge, prediction and annotation-growth timeline
DatasetsNot extracted or verified for this record.
OrganismsNot extracted or verified for this record.
AssaysNot extracted or verified for this record.
SplitsNot extracted or verified for this record.
AdaptationNot extracted or verified for this record.
BaselinesNot extracted or verified for this record.

How it works

Procedure overview

Conceptual overview of the cited procedure; consult the pinned source for executable settings.

Procedure overviewRelease target sequences. Then: Submit functions. Then: Accumulate new annotations. Then: Assess predictionsRelease target sequencesSubmit functionsAccumulate new annotationsAssess predictions
Read the diagram as text
  1. Release target sequences
  2. Submit functions
  3. Accumulate new annotations
  4. Assess predictions
cafa official source · Official CAFA page: The CAFA Challenge, prediction and annotation-growth timeline

Procedure

Submit ontology-term predictions before the deadline. Proteins receiving experimental annotations after submission become evaluation targets for that challenge round.

cafa official source · Official CAFA page: The CAFA Challenge, prediction and annotation-growth timeline

Tested models and results

Release 2026-09-16-d74d282221a9 · 0 evaluations · 0 metric rows. Different protocols are not a single leaderboard.

No evaluations linked in this release.

Strengths and limitations

Strengths supported by sources

  • Uses later experimental annotations to assess predictions made in advance.cafa official source · Official CAFA page: The CAFA Challenge, prediction and annotation-growth timeline

Limitations and conditions

  • Only proteins that acquire suitable annotations enter the assessed set; ontology version, round and scoring rules must be recorded.cafa official source · Official CAFA page: The CAFA Challenge, prediction and annotation-growth timeline
Profile review details

Primary-source description checked by an automated research assistant. This is a profile review, not an independent execution or numerical reproduction.

Stable record: discovery-benchmark-cafa

Applicable tests and references

Applicability is distinct from a completed evaluation.

Sources and history

Release 2026-09-16-d74d282221a9 · Record review: discovered

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Technical metadata and extraction receipts

Stable ID: discovery-benchmark-cafa

areas
protein-function
entity level
challenge
missing metadata
dataset release: unextracted; metric implementation: unextracted; split manifest: unextracted; version: unextracted
scope note
Specialist molecular or omics evaluation; protocol details require review before numerical comparison.
task
Protein function prediction challenge
version
Not reported
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