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Configuration

Human-Geneformer

Human-Geneformer is the human-pretrained reference used to evaluate the value of mouse-specific pretraining.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)

1 evaluation · 1 metric row

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. Expression profiles mapped to the human model’s gene representation. Then: 2. Human-Geneformer. Then: 3. Gene/cell embeddings and downstream cell-type predictionsEvaluated procedure (conceptual)1. Expression profiles mapped to the human model’s gene representation. Then: 2. Human-Geneformer. Then: 3. Gene/cell embeddings and downstream cell-type predictionsEvaluated procedure (conceptual)1. Expression profiles mapped to the human model’s gene representation. Then: 2. Human-Geneformer. Then: 3. Gene/cell embeddings and downstream cell-type predictions

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1)

At a glance

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
Human-Geneformer: Human thymus cell-type classification

Native human model; zero-shot setting.

Independent external evaluation · Evaluation metadata: needs review

74.48 F1

Unit: % · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Table 4, h/ Thymus row, Human-Geneformer Zero-shot F1 column

Source checking is not independent reproduction.

How it works

How the evaluated method works

Rank Value Encoding feeds the original Geneformer transformer encoder before adaptation to the study’s downstream tasks.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1)
Underlying method and version boundaries

Geneformer ranks genes by expression scaled against its pretraining corpus, then uses a transformer encoder with a masked-gene objective. V1 and V2 have different corpora, vocabularies, sizes and context limits, so a historical paper name is not replaced with today’s default checkpoint.

Sourceshuggingface.co/ctheodoris/Geneformer README.md · README.md; introduction, model description, pretrained-model and usage sections at pinned revision
What was evaluated

The linked evaluation record identifies Human-Geneformer: Human thymus cell-type classification. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-lit-b3-004

Strengths and limitations

Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-10d85f2a035720

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeSingle-cell transformer; this record is the paper-specific evaluated configuration.
Sourceshuggingface.co/ctheodoris/Geneformer README.md · README.md model description
Architecture / procedureRank Value Encoding feeds the original Geneformer transformer encoder before adaptation to the study’s downstream tasks.
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1)
Biological inputsExpression profiles mapped to the human model’s gene representation
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/In silico perturbation of human data using mouse-Geneformer (paragraph 1); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1)
OutputsGene/cell embeddings and downstream cell-type predictions
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1); Discussion (paragraph 1)
ParametersAn aggregate parameter total for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sources
Sources (2)Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility; huggingface.co/ctheodoris/Geneformer README.md · Materials and methods/Construction of the mouse-Geneformer/Architecture.; Materials and methods/Construction of the mouse-Geneformer/Construction of mouse-Genecoupus-20M.; Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer.; Materials and methods/Fine-turning of the mouse-Geneformer; Materials and methods/Cell type classification using the mouse-Geneformer and conventional methods; Materials and methods/Cell type classification using mouse-Geneformer with and without prior learning; Materials and methods/In silico perturbation experiments; Materials and methods/Gene name conversion between mouse and human for cross-species application; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision
Known versions / configurationHuman-Geneformer is the comparison-table label; that label does not specify an immutable weight revision. · Not reported in inspected sources
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingApproximately 30 million human single-cell transcriptomes in the original comparator described by this paper.
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Results/Development of mouse-Geneformer (paragraph 1)
Context limitsA maximum input/context length for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sources
Sources (2)Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility; huggingface.co/ctheodoris/Geneformer README.md · Materials and methods/Construction of the mouse-Geneformer/Architecture.; Materials and methods/Construction of the mouse-Geneformer/Construction of mouse-Genecoupus-20M.; Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer.; Materials and methods/Fine-turning of the mouse-Geneformer; Materials and methods/Cell type classification using the mouse-Geneformer and conventional methods; Materials and methods/Cell type classification using mouse-Geneformer with and without prior learning; Materials and methods/In silico perturbation experiments; Materials and methods/Gene name conversion between mouse and human for cross-species application; inspected for explicit maximum input length (dataset lengths and family-wide limits are not substituted); README.md at pinned repository revision
AccessOfficial upstream implementation and usage documentation: https://huggingface.co/ctheodoris/Geneformer/blob/1f7fbae4e469a5f4f1af8c111a529cfe1b3829f5/README.md. This pinned documentation revision is not automatically the evaluated weight revision.
Sourceshuggingface.co/ctheodoris/Geneformer README.md · README.md; installation, model download and usage instructions
Code licenceNo explicit code licence was established from the paper’s availability statement and inspected repository-root documentation. · Not reported in inspected sources
Sourceshuggingface.co/ctheodoris/Geneformer README.md · README.md and repository-root licence-file search
Weights licenceApache 2.0 is declared in the official Geneformer model-card metadata; the exact historical configuration still needs its checkpoint identity.
Sourceshuggingface.co/ctheodoris/Geneformer README.md · README.md front matter, license field; model-version list

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

22 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Expression profiles mapped to the human model’s gene representation","Human-Geneformer","Gene/cell embeddings and downstream cell-type predictions"]

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Single-cell transformer; this record is the paper-specific evaluated configuration.

Individual claims
huggingface.co/ctheodoris/Geneformer README.md

Original source ↗

README.md model description

Version: 1f7fbae4e469a5f4f1af8c111a529cfe1b3829f5
Retrieved: 2026-09-16T19:46:20.640731+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 56d6e570b349cbedae9a54634421c94e7af8ea467ce0fdd79193372ae3cbdbd8

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

Rank Value Encoding feeds the original Geneformer transformer encoder before adaptation to the study’s downstream tasks.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

Apache 2.0 is declared in the official Geneformer model-card metadata; the exact historical configuration still needs its checkpoint identity.

Individual claims
huggingface.co/ctheodoris/Geneformer README.md

Original source ↗

README.md front matter, license field; model-version list

Version: 1f7fbae4e469a5f4f1af8c111a529cfe1b3829f5
Retrieved: 2026-09-16T19:46:20.640731+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 56d6e570b349cbedae9a54634421c94e7af8ea467ce0fdd79193372ae3cbdbd8

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

Expression profiles mapped to the human model’s gene representation

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/In silico perturbation of human data using mouse-Geneformer (paragraph 1); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

Gene/cell embeddings and downstream cell-type predictions

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1); Discussion (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources.

Individual claims
huggingface.co/ctheodoris/Geneformer README.md

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Architecture.; Materials and methods/Construction of the mouse-Geneformer/Construction of mouse-Genecoupus-20M.; Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer.; Materials and methods/Fine-turning of the mouse-Geneformer; Materials and methods/Cell type classification using the mouse-Geneformer and conventional methods; Materials and methods/Cell type classification using mouse-Geneformer with and without prior learning; Materials and methods/In silico perturbation experiments; Materials and methods/Gene name conversion between mouse and human for cross-species application; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 1f7fbae4e469a5f4f1af8c111a529cfe1b3829f5
Retrieved: 2026-09-16T19:46:20.640731+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 56d6e570b349cbedae9a54634421c94e7af8ea467ce0fdd79193372ae3cbdbd8

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Architecture.; Materials and methods/Construction of the mouse-Geneformer/Construction of mouse-Genecoupus-20M.; Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer.; Materials and methods/Fine-turning of the mouse-Geneformer; Materials and methods/Cell type classification using the mouse-Geneformer and conventional methods; Materials and methods/Cell type classification using mouse-Geneformer with and without prior learning; Materials and methods/In silico perturbation experiments; Materials and methods/Gene name conversion between mouse and human for cross-species application; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-10d85f2a035720

areas
cells-tissues
entity level
method
version
Not reported
reported name
Human-Geneformer
historical missing metadata
version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: mouse-geneformer-2025; evidence-reported-base-geneformer-readme-md; source locator: Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1) | README.md model description | Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1); ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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