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ADAR-GPT continual

ADAR-GPT is a supervised RNA-editing classifier obtained by continually fine-tuning GPT-4o-mini on marked RNA sequence windows.

SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Results and Analysis (paragraph 1); Materials and Methods/Fine-Tuning Protocol. (paragraph 4)

1 evaluation · 1 metric row

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. 201-nt RNA windows with the target adenosine explicitly marked. Then: 2. ADAR-GPT continual. Then: 3. A-to-I editing-site classification at the study’s editing thresholdEvaluated procedure (conceptual)1. 201-nt RNA windows with the target adenosine explicitly marked. Then: 2. ADAR-GPT continual. Then: 3. A-to-I editing-site classification at the study’s editing thresholdEvaluated procedure (conceptual)1. 201-nt RNA windows with the target adenosine explicitly marked. Then: 2. ADAR-GPT continual. Then: 3. A-to-I editing-site classification at the study’s editing threshold

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)

At a glance

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
ADAR-GPT continual: A-to-I RNA editing site prediction

Curriculum plus 15% fine-tuning; 201-nt sequence windows; decision threshold 0.5

Author-reported evaluation · Evaluation metadata: needs review

0.763 F1

Unit: fraction · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Table 2, Adar-GPT (continual) row, F1 column

Source checking is not independent reproduction.

How it works

How the evaluated method works

The continual configuration first trains on progressively ordered editing-threshold data and then refines on sites meeting the 15% editing threshold. This is a task-specific fine-tuned pipeline, not an evaluation of the unadapted general-purpose model.

SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)
What was evaluated

The linked evaluation record identifies ADAR-GPT continual: A-to-I RNA editing site prediction. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-lit-b4-005

Strengths and limitations

Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-1d2aa9880a1c77

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeStudy-specific predictive method; this record is the paper-specific evaluated configuration.
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)
Architecture / procedureThe continual configuration first trains on progressively ordered editing-threshold data and then refines on sites meeting the 15% editing threshold. This is a task-specific fine-tuned pipeline, not an evaluation of the unadapted general-purpose model.
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)
Biological inputs201-nt RNA windows with the target adenosine explicitly marked
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Materials and Methods/Input Representation. (paragraph 1); Methodology/Data Collection and Preprocessing—Liver GTEx Dataset. (paragraph 5)
OutputsA-to-I editing-site classification at the study’s editing threshold
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Materials and Methods/Dataset Design and Labeling. (paragraph 1); Contribution. (paragraph 1)
ParametersThe paper identifies GPT-4o-mini but does not disclose the backbone parameter count. · Not reported in inspected sources
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Results and Analysis (paragraph 1); Materials and Methods/Fine-Tuning Protocol. (paragraph 4)
Known versions / configurationADAR-GPT continual is the comparison-table label; that label does not specify an immutable weight revision. · Not reported in inspected sources
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingGTEx liver data from 131 samples; curriculum thresholds 1%, 5%, 10% and 15%, followed by refinement on 15% sites.
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Methodology/Data Collection and Preprocessing—Liver GTEx Dataset. (paragraph 3)
Context limits201 nucleotides: 100 upstream, central adenosine and 100 downstream
SourcesADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites · Methodology/Data Collection and Preprocessing—Liver GTEx Dataset. (paragraph 5); Table t03 (paragraph 1)
AccessOfficial study implementation and usage documentation: https://github.com/Scientific-Computing-Lab/ADAR-GPT/blob/c0fd23679922d91a45520455d4ca0202a5ca609f/README.md. This pinned documentation revision is not automatically the evaluated weight revision.
SourcesScientific-Computing-Lab/ADAR-GPT README.md · README.md; installation, model download and usage instructions
Code licenceMIT (study repository code at the cited revision; this does not establish every dependency or historical checkpoint licence).
SourcesScientific-Computing-Lab/ADAR-GPT LICENSE · LICENSE; complete licence text
Weights licenceThe inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately. · Not reported in inspected sources
SourcesScientific-Computing-Lab/ADAR-GPT README.md · README.md; checkpoint/access documentation and licence scope

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

19 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["201-nt RNA windows with the target adenosine explicitly marked","ADAR-GPT continual","A-to-I editing-site classification at the study’s editing threshold"]

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Study-specific predictive method; this record is the paper-specific evaluated configuration.

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

The continual configuration first trains on progressively ordered editing-threshold data and then refines on sites meeting the 15% editing threshold. This is a task-specific fine-tuned pipeline, not an evaluation of the unadapted general-purpose model.

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

The inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately.

Individual claims
Scientific-Computing-Lab/ADAR-GPT README.md

Original source ↗

README.md; checkpoint/access documentation and licence scope

Version: c0fd23679922d91a45520455d4ca0202a5ca609f
Retrieved: 2026-09-16T19:54:12.011620+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: ae16bae98ce731633c412a0279285112ebe40db0f867907bd0caa91fce66ded8

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

201-nt RNA windows with the target adenosine explicitly marked

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Materials and Methods/Input Representation. (paragraph 1); Methodology/Data Collection and Preprocessing—Liver GTEx Dataset. (paragraph 5)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

A-to-I editing-site classification at the study’s editing threshold

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Materials and Methods/Dataset Design and Labeling. (paragraph 1); Contribution. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

The paper identifies GPT-4o-mini but does not disclose the backbone parameter count.

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Results and Analysis (paragraph 1); Materials and Methods/Fine-Tuning Protocol. (paragraph 4)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Known versions / configuration

ADAR-GPT continual is the comparison-table label; that label does not specify an immutable weight revision.

Individual claims
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Original source ↗

Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: cc8c7eb928f246f1f347a8822f614cd3475381c35eef6d579032ce441580198e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

3 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-1d2aa9880a1c77

areas
rna-transcriptomes
entity level
method
version
Not reported
reported name
ADAR-GPT continual
historical missing metadata
version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: adar-gpt-editing-2026; source locator: Methodology/Model Training Approaches—Static vs. Continual Fine-Tuning. (paragraph 4); Contribution. (paragraph 1) | Results and Analysis (paragraph 1); Materials and Methods/Fine-Tuning Protocol. (paragraph 4); ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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