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Configuration

RNAfold

RNAfold is the thermodynamic RNA-structure baseline in the BPfold comparison.

SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Abstract (paragraph 2); Methods/Datasets and evaluation (paragraph 1)

1 evaluation · 4 metric rows

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. RNA nucleotide sequence. Then: 2. RNAfold. Then: 3. RNA secondary structureEvaluated procedure (conceptual)1. RNA nucleotide sequence. Then: 2. RNAfold. Then: 3. RNA secondary structureEvaluated procedure (conceptual)1. RNA nucleotide sequence. Then: 2. RNAfold. Then: 3. RNA secondary structure

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1)

At a glance

Model type

Thermodynamic RNA folding algorithm; this record is the paper-specific evaluated configuration.

SourcesViennaRNA/ViennaRNA README.md · README.md model description

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 4 metric rows. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
RNAfold: RNA secondary structure

Family-wise RNA secondary-structure evaluation; macro-average canonical base-pair metrics.

Independent external evaluation · Evaluation metadata: needs review

0.747 F1

Unit: unitless · Direction: higher

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedDeep generalizable prediction of RNA secondary structure via base pair motif energy · Table 2, RNAfold row, PDB F1 column

Source checking is not independent reproduction.

0.776 Precision

Unit: unitless · Direction: higher

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedDeep generalizable prediction of RNA secondary structure via base pair motif energy · Table 2 (Tab2), row 10 RNAfold, column 8: PDB Precision

Source checking is not independent reproduction.

0.728 Recall

Unit: unitless · Direction: higher

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedDeep generalizable prediction of RNA secondary structure via base pair motif energy · Table 2 (Tab2), row 10 RNAfold, column 9: PDB Recall

Source checking is not independent reproduction.

0.749 INF

Unit: unitless · Direction: higher

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedDeep generalizable prediction of RNA secondary structure via base pair motif energy · Table 2 (Tab2), row 10 RNAfold, column 6: PDB INF

Source checking is not independent reproduction.

How it works

How the evaluated method works

ViennaRNA predicts a minimum-free-energy secondary structure using its thermodynamic energy model; the paper runs default settings.

SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1)
Underlying method and version boundaries

The ViennaRNA package computes minimum-free-energy structures, partition functions and associated structure probabilities. RNAfold is a procedure with energy parameters, not a neural language-model checkpoint.

SourcesViennaRNA/ViennaRNA README.md · README.md; introduction, model description, pretrained-model and usage sections at pinned revision
What was evaluated

The linked evaluation record identifies RNAfold: RNA secondary structure. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-lit-012

Strengths and limitations

Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-52eee4cc67ca26

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeThermodynamic RNA folding algorithm; this record is the paper-specific evaluated configuration.
SourcesViennaRNA/ViennaRNA README.md · README.md model description
Architecture / procedureViennaRNA predicts a minimum-free-energy secondary structure using its thermodynamic energy model; the paper runs default settings.
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1)
Biological inputsRNA nucleotide sequence
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Methods/Deep neural network with base pair attention (paragraph 5); Introduction (paragraph 1)
OutputsRNA secondary structure
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Methods/Datasets and evaluation (paragraph 1); Discussion (paragraph 5)
ParametersNot applicable as a neural parameter count. · Not applicable
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Methods/Training strategy and structure refinement (paragraph 3); Results/Assessing the effectiveness of base pair motif energy (paragraph 3)
Known versions / configurationViennaRNA RNAfold version 2.6.4 · Not reported in inspected sources
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingExperimentally informed thermodynamic parameters rather than neural pretraining.
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Methods/Training strategy and structure refinement (paragraph 3); Results/Evaluating BPfold on family-wise datasets (paragraph 3)
Context limitsRNA length is constrained by the RNAfold implementation, algorithm and available memory; there is no learned fixed-token context window. · Not applicable
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Supplementary information (paragraph 1); Code availability (paragraph 1)
AccessOfficial upstream implementation and usage documentation: https://github.com/ViennaRNA/ViennaRNA/blob/1ffec79f5e258896160f7362ced8263450f371dc/README.md. This pinned documentation revision is not automatically the evaluated weight revision.
SourcesViennaRNA/ViennaRNA README.md · README.md; installation, model download and usage instructions
Code licenceViennaRNA licence/disclaimer; see the pinned full text for scope and conditions. (upstream repository code at the cited revision; this does not establish every dependency or historical checkpoint licence).
SourcesViennaRNA/ViennaRNA license.txt · license.txt; complete licence text
Weights licenceNot applicable: RNAfold uses thermodynamic energy parameters rather than pretrained neural weights. · Not applicable
SourcesDeep generalizable prediction of RNA secondary structure via base pair motif energy · Methods/Training strategy and structure refinement (paragraph 3); Discussion (paragraph 2)

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

20 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["RNA nucleotide sequence","RNAfold","RNA secondary structure"]

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Thermodynamic RNA folding algorithm; this record is the paper-specific evaluated configuration.

Individual claims
ViennaRNA/ViennaRNA README.md

Original source ↗

README.md model description

Version: 1ffec79f5e258896160f7362ced8263450f371dc
Retrieved: 2026-09-16T20:00:00.820987+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: d37146b01e4273062a5230c496a9af8414ee7ef14fcd905cf415959256d59c4e

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

ViennaRNA predicts a minimum-free-energy secondary structure using its thermodynamic energy model; the paper runs default settings.

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

Not applicable: RNAfold uses thermodynamic energy parameters rather than pretrained neural weights.

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Methods/Training strategy and structure refinement (paragraph 3); Discussion (paragraph 2)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

inapplicable

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

RNA nucleotide sequence

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Methods/Deep neural network with base pair attention (paragraph 5); Introduction (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

RNA secondary structure

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Methods/Datasets and evaluation (paragraph 1); Discussion (paragraph 5)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

Not applicable as a neural parameter count.

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Methods/Training strategy and structure refinement (paragraph 3); Results/Assessing the effectiveness of base pair motif energy (paragraph 3)

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

inapplicable

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Known versions / configuration

ViennaRNA RNAfold version 2.6.4

Individual claims
Deep generalizable prediction of RNA secondary structure via base pair motif energy

Original source ↗

Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.

Version: version of record
Retrieved: 2026-09-16T10:41:16.502000+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: 976218bd172998a1a6e7ed1609ecb8cb2ee380fb48a8dc7b25bc05ea8b0a49af

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

3 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-52eee4cc67ca26

areas
rna-transcriptomes
entity level
method
version
Not reported
reported name
RNAfold
historical missing metadata
version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: bpfold-2025; evidence-reported-base-rnafold-readme-md; source locator: Abstract (paragraph 2); Methods/Base pair motif energy as thermodynamic prior (paragraph 1) | README.md model description | Abstract (paragraph 2); Methods/Datasets and evaluation (paragraph 1); ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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