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Cell-DINO ViT-L

Cell-DINO ViT-L learns representations of fluorescent cell images, including protein-localisation information.

SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Results/Cell-DINO outperforms standard supervised ViT (paragraph 3); Results/Cell-DINO outperforms alternative self-supervised strategies (paragraph 3)

1 evaluation · 1 metric row

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. Fluorescence-microscopy cell images. Then: 2. Cell-DINO ViT-L. Then: 3. Cell-image embeddings and downstream protein-localisation predictionsEvaluated procedure (conceptual)1. Fluorescence-microscopy cell images. Then: 2. Cell-DINO ViT-L. Then: 3. Cell-image embeddings and downstream protein-localisation predictionsEvaluated procedure (conceptual)1. Fluorescence-microscopy cell images. Then: 2. Cell-DINO ViT-L. Then: 3. Cell-image embeddings and downstream protein-localisation predictions

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)

At a glance

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
Cell-DINO ViT-L: protein localization classification

Self-supervised microscopy embedding pre-trained on HPA-FoV; downstream protein-localization classifier. Dataset-specific pretraining; the paper does not claim a general-purpose foundation model that generalizes beyond these benchmarks.

Author-reported evaluation · Evaluation metadata: needs review

65.5% F1

Unit: percent · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Table 2, HPA-FoV section, Cell-DINO row, PL column

Source checking is not independent reproduction.

How it works

How the evaluated method works

DINOv2 self-supervised learning trains a vision transformer on cell images. Frozen embeddings support downstream classifiers; the protein-localisation experiment includes a separately trained two-layer classifier.

SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)
What was evaluated

The linked evaluation record identifies Cell-DINO ViT-L: protein localization classification. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-lit-b4-015

Strengths and limitations

Limitations and conditions

Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-808b23c65fbc89

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeVision transformer; this record is the paper-specific evaluated configuration.
SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)
Architecture / procedureDINOv2 self-supervised learning trains a vision transformer on cell images. Frozen embeddings support downstream classifiers; the protein-localisation experiment includes a separately trained two-layer classifier.
SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)
Biological inputsFluorescence-microscopy cell images
SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Methods/Cell-DINO algorithm (paragraph 1); Methods/Datasets (paragraph 5)
OutputsCell-image embeddings and downstream protein-localisation predictions
SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Results/Cell-DINO outperforms standard supervised ViT (paragraph 3); Results/Cell-DINO outperforms standard supervised ViT (paragraph 1)
ParametersThe HPA-SC downstream two-layer classifier has 1.2 million supervised parameters; this is not the total of the frozen ViT-L encoder plus classifier.
SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Results/Cell-DINO reduces the dependency on manual annotations (paragraph 1); Results/Cell-DINO is competitive against highly tuned models (paragraph 1)
Known versions / configurationCell-DINO ViT-L is the comparison-table label; that label does not specify an immutable weight revision. · Not reported in inspected sources
SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingSeparate ViT-L pretraining datasets: HPA-FoV about 200,000 images, HPA-SC about 500,000 images, and combined Cell Painting about five million images. The protein-localisation classifier is trained separately.
SourcesCell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy · Methods/Computational resources used for training Cell-DINO models (paragraph 1); Methods/Datasets (paragraph 4)
Context limitsA maximum input/context length for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sources
Sources (2)Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy; facebookresearch/dinov2 docs/README_CELL_DINO.md · Methods/Datasets; Methods/Cell-DINO algorithm; Methods/Vision Transformer (ViT) architecture; Methods/Supervised ViTs; Methods/Training and evaluation protocol on HPA datasets; Methods/Kaggle evaluation protocol; Methods/Cell Painting evaluation protocol; Methods/Baselines; inspected for explicit maximum input length (dataset lengths and family-wide limits are not substituted); docs/README_CELL_DINO.md at pinned repository revision
AccessOfficial study implementation and usage documentation: https://github.com/facebookresearch/dinov2/blob/7764ea0f912e53c92e82eb78a2a1631e92725fc8/docs/README_CELL_DINO.md. This pinned documentation revision is not automatically the evaluated weight revision.
Sourcesfacebookresearch/dinov2 docs/README_CELL_DINO.md · docs/README_CELL_DINO.md; installation, model download and usage instructions
Code licenceConflicting official statements: the Cell-DINO README says CC BY-NC, but its linked code licence is headed Creative Commons Attribution 4.0 International. Code reuse terms require author clarification; the DINOv2 root licence is not substituted. · Not reported in inspected sources
Sources (2)facebookresearch/dinov2 docs/README_CELL_DINO.md; facebookresearch/dinov2 LICENSE_CELL_DINO_CODE · docs/README_CELL_DINO.md / License; linked LICENSE_CELL_DINO_CODE heading and grant
Weights licenceFAIR Noncommercial Research License, version 1 (18 August 2025), for the Cell-DINO model materials.
Sourcesfacebookresearch/dinov2 LICENSE_CELL_DINO_MODELS · LICENSE_CELL_DINO_MODELS; title, definitions and Section 1

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

21 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Fluorescence-microscopy cell images","Cell-DINO ViT-L","Cell-image embeddings and downstream protein-localisation predictions"]

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Vision transformer; this record is the paper-specific evaluated configuration.

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

DINOv2 self-supervised learning trains a vision transformer on cell images. Frozen embeddings support downstream classifiers; the protein-localisation experiment includes a separately trained two-layer classifier.

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

FAIR Noncommercial Research License, version 1 (18 August 2025), for the Cell-DINO model materials.

Individual claims
facebookresearch/dinov2 LICENSE_CELL_DINO_MODELS

Original source ↗

LICENSE_CELL_DINO_MODELS; title, definitions and Section 1

Version: 7764ea0f912e53c92e82eb78a2a1631e92725fc8
Retrieved: 2026-09-16T20:30:16.572226+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: d779b47a4ef8bbfc6c90d14768fe6a0a2c1c08bbc3712084496058bfd83cef4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

Fluorescence-microscopy cell images

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Methods/Cell-DINO algorithm (paragraph 1); Methods/Datasets (paragraph 5)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

Cell-image embeddings and downstream protein-localisation predictions

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Results/Cell-DINO outperforms standard supervised ViT (paragraph 3); Results/Cell-DINO outperforms standard supervised ViT (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

The HPA-SC downstream two-layer classifier has 1.2 million supervised parameters; this is not the total of the frozen ViT-L encoder plus classifier.

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Results/Cell-DINO reduces the dependency on manual annotations (paragraph 1); Results/Cell-DINO is competitive against highly tuned models (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Known versions / configuration

Cell-DINO ViT-L is the comparison-table label; that label does not specify an immutable weight revision.

Individual claims
Cell-DINO: Self-supervised image-based embeddings for cell fluorescent microscopy

Original source ↗

Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: 12a53a78c70b3033c3351cf7afd4da42ebc98bb3281308f07e71e5baffc153a0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

4 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-808b23c65fbc89

areas
cells-tissues
entity level
method
version
Not reported
reported name
Cell-DINO ViT-L
historical missing metadata
version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: cell-dino-2025; source locator: Results/Cell-DINO is competitive against highly tuned models (paragraph 1); Results/Cell-DINO outperforms standard supervised ViT (paragraph 3) | Results/Cell-DINO outperforms standard supervised ViT (paragraph 3); Results/Cell-DINO outperforms alternative self-supervised strategies (paragraph 3); ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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