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Mouse-Geneformer

Mouse-Geneformer adapts the Geneformer transformer design to mouse single-cell transcriptomes.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Results/In silico perturbation experiments/In silico perturbation experiment in COP1 KO microglia. (paragraph 2); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1)

1 evaluation · 1 metric row

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. Rank-encoded mouse single-cell transcriptomes. Then: 2. Mouse-Geneformer. Then: 3. Gene/cell representations and adapted cell-type or perturbation analysesEvaluated procedure (conceptual)1. Rank-encoded mouse single-cell transcriptomes. Then: 2. Mouse-Geneformer. Then: 3. Gene/cell representations and adapted cell-type or perturbation analysesEvaluated procedure (conceptual)1. Rank-encoded mouse single-cell transcriptomes. Then: 2. Mouse-Geneformer. Then: 3. Gene/cell representations and adapted cell-type or perturbation analyses

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)

At a glance

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
Mouse-Geneformer: Human thymus cell-type classification

Ortholog-based gene conversion; zero-shot mouse model on human cells.

Author-reported evaluation · Evaluation metadata: needs review

48.57 F1

Unit: % · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Table 4, h/ Thymus row, Mouse-Geneformer Zero-shot F1 column

Source checking is not independent reproduction.

How it works

How the evaluated method works

Rank Value Encoding orders genes by expression-derived values for a transformer encoder. The mouse model follows the human Geneformer design with minor modifications and mouse-specific pretraining.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)
What was evaluated

The linked evaluation record identifies Mouse-Geneformer: Human thymus cell-type classification. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-lit-b3-003

Strengths and limitations

Limitations and conditions

  • In-silico perturbation scores are model predictions; validation of selected genes does not validate every predicted regulatory relationship.
    SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/In silico perturbation of human data using mouse-Geneformer 2: COVID-19 human blood. (paragraph 1); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion (paragraph 2)
Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-e2f2f0d4830bb0

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeTransformer representation pipeline; this record is the paper-specific evaluated configuration.
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)
Architecture / procedureRank Value Encoding orders genes by expression-derived values for a transformer encoder. The mouse model follows the human Geneformer design with minor modifications and mouse-specific pretraining.
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)
Biological inputsRank-encoded mouse single-cell transcriptomes
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Results/In silico perturbation experiments/In silico perturbation experiment in COP1 KO microglia. (paragraph 2); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1)
OutputsGene/cell representations and adapted cell-type or perturbation analyses
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Introduction (paragraph 4); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1)
ParametersSix transformer blocks, four heads and 256-dimensional embeddings are specified; a total parameter count is not reported in Table 1. · Not reported in inspected sources
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Table1 Summary of Experimental conditions
Known versions / configurationMouse-Geneformer is the comparison-table label; that label does not specify an immutable weight revision. · Not reported in inspected sources
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingApproximately 21 million mouse single-cell RNA-seq profiles; the human comparator was pretrained separately on human cells.
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Results/Development of mouse-Geneformer (paragraph 1); Results/Cell type classification: pretraining is effective (paragraph 1)
Context limits2,048 gene tokens (Table 1); six transformer blocks, four attention heads and 256-dimensional embeddings.
SourcesMouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility · Table1; Input max dimensions row
AccessOfficial study implementation and usage documentation: https://github.com/machine-perception-robotics-group/Mouse-Geneformer/blob/ed17d455193ed4c4d93230a8f5f2de349cf20c81/README.md. This pinned documentation revision is not automatically the evaluated weight revision.
Sourcesmachine-perception-robotics-group/Mouse-Geneformer README.md · README.md; installation, model download and usage instructions
Code licenceNo explicit code licence was established from the paper’s availability statement and inspected repository-root documentation. · Not reported in inspected sources
Sourcesmachine-perception-robotics-group/Mouse-Geneformer README.md · README.md and repository-root licence-file search
Weights licenceThe inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately. · Not reported in inspected sources
Sourcesmachine-perception-robotics-group/Mouse-Geneformer README.md · README.md; checkpoint/access documentation and licence scope

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

19 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Rank-encoded mouse single-cell transcriptomes","Mouse-Geneformer","Gene/cell representations and adapted cell-type or perturbation analyses"]

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Transformer representation pipeline; this record is the paper-specific evaluated configuration.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

Rank Value Encoding orders genes by expression-derived values for a transformer encoder. The mouse model follows the human Geneformer design with minor modifications and mouse-specific pretraining.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

The inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately.

Individual claims
machine-perception-robotics-group/Mouse-Geneformer README.md

Original source ↗

README.md; checkpoint/access documentation and licence scope

Version: ed17d455193ed4c4d93230a8f5f2de349cf20c81
Retrieved: 2026-09-16T19:54:18.217286+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 1eefd8677ff2644f55272a1412cf612e1264f92456ae3b701598d9a5b558bc4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

Rank-encoded mouse single-cell transcriptomes

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Results/In silico perturbation experiments/In silico perturbation experiment in COP1 KO microglia. (paragraph 2); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

Gene/cell representations and adapted cell-type or perturbation analyses

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Introduction (paragraph 4); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

Six transformer blocks, four heads and 256-dimensional embeddings are specified; a total parameter count is not reported in Table 1.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Table1 Summary of Experimental conditions

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Known versions / configuration

Mouse-Geneformer is the comparison-table label; that label does not specify an immutable weight revision.

Individual claims
Mouse-Geneformer: A deep learning model for mouse single-cell transcriptome and its cross-species utility

Original source ↗

Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.

Version: version of record
Retrieved: 2026-09-16T10:44:03.392488+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: ef6c68f5c9b47c2f89598ddf647f05b72e4155e8b33609ebff23936a84bbd41d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-e2f2f0d4830bb0

areas
cells-tissues
entity level
method
version
Not reported
reported name
Mouse-Geneformer
historical missing metadata
version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: mouse-geneformer-2025; source locator: Materials and methods/Construction of the mouse-Geneformer/Pretraining of the mouse-Geneformer. (paragraph 1); Materials and methods/Construction of the mouse-Geneformer/Architecture. (paragraph 1) | Results/In silico perturbation experiments/In silico perturbation experiment in COP1 KO microglia. (paragraph 2); Results/Cross-species application of mouse-Geneformer through orthologous gene name conversion/Human cell type classification using mouse-Geneformer. (paragraph 1); ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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