Dataset

Human RNA 2OMe sites, independent test set

Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evaluation results

Release 2026-09-17-d277315f7d76 · 5 evaluations · 35 metric rows. Different protocols are not a single leaderboard.

Evaluation setupMetricEvidence origin

Results grouped by the exact reported evaluation
Metric and finding	Coverage and uncertainty	Evidence
BERT2OME: Human RNA 2OMe sites, independent test set Configuration: BERT2OMEProtocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction)Dataset: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Independent external evaluation · Evaluation metadata: needs review
0.795 ACC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC Source checking is not independent reproduction.
0.813 Precision Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 4: Human RNA 2OMe sites, independent test set Precision Source checking is not independent reproduction.
0.788 F1-score Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 3: Human RNA 2OMe sites, independent test set F1-score Source checking is not independent reproduction.
0.878 AUC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 6: Human RNA 2OMe sites, independent test set AUC Source checking is not independent reproduction.
2OMe-LM: Human RNA 2OMe sites, independent test set Configuration: 2OMe-LMProtocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction)Dataset: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Author-reported evaluation · Evaluation metadata: needs review
0.963 AUPR Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 7: Human RNA 2OMe sites, independent test set AUPR Source checking is not independent reproduction.
0.898 ACC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Source checking is not independent reproduction.
0.952 AUC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 6: Human RNA 2OMe sites, independent test set AUC Source checking is not independent reproduction.
0.802 Recall Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 5: Human RNA 2OMe sites, independent test set Recall Source checking is not independent reproduction.
0.887 F1-score Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 3: Human RNA 2OMe sites, independent test set F1-score Source checking is not independent reproduction.
0.993 Precision Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 4: Human RNA 2OMe sites, independent test set Precision Source checking is not independent reproduction.
H2Opred: Human RNA 2OMe sites, independent test set Configuration: H2OpredProtocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction)Dataset: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Independent external evaluation · Evaluation metadata: needs review
0.800 F1-score Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 3: Human RNA 2OMe sites, independent test set F1-score Source checking is not independent reproduction.
0.904 AUPR Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 7: Human RNA 2OMe sites, independent test set AUPR Source checking is not independent reproduction.
0.819 ACC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC Source checking is not independent reproduction.
0.890 Precision Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 4: Human RNA 2OMe sites, independent test set Precision Source checking is not independent reproduction.
0.648 MCC Unit: unitless · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 8: Human RNA 2OMe sites, independent test set MCC Source checking is not independent reproduction.
Meta-2OM: Human RNA 2OMe sites, independent test set Configuration: Meta-2OMProtocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction)Dataset: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Independent external evaluation · Evaluation metadata: needs review
0.881 AUPR Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 7: Human RNA 2OMe sites, independent test set AUPR Source checking is not independent reproduction.
0.891 Precision Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 4: Human RNA 2OMe sites, independent test set Precision Source checking is not independent reproduction.
0.780 ACC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC Source checking is not independent reproduction.
0.639 Recall Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 5: Human RNA 2OMe sites, independent test set Recall Source checking is not independent reproduction.
0.584 MCC Unit: unitless · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 8: Human RNA 2OMe sites, independent test set MCC Source checking is not independent reproduction.
NmRF: Human RNA 2OMe sites, independent test set Configuration: NmRFProtocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction)Dataset: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Independent external evaluation · Evaluation metadata: needs review
0.624 F1-score Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 3: Human RNA 2OMe sites, independent test set F1-score Source checking is not independent reproduction.
0.586 AUC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 6: Human RNA 2OMe sites, independent test set AUC Source checking is not independent reproduction.
0.508 Precision Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 4: Human RNA 2OMe sites, independent test set Precision Source checking is not independent reproduction.
0.512 ACC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC Source checking is not independent reproduction.
0.030 MCC Unit: unitless · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checked2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 8: Human RNA 2OMe sites, independent test set MCC Source checking is not independent reproduction.

Evidence table

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

6 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statement	Original source and location	Review and provenance
attributes.reported_population No value recorded Context-only references	2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model Original source ↗ Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z	missing or unspecified No individual claim review recorded Audit details Field: `attributes.reported_population` Source artifact SHA-256: `54fe4db6f35c03d0d4f3ef4da720eb26a832199372c56d0956609ff07af750ee` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.source_locator Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Context-only references	2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model Original source ↗ Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `54fe4db6f35c03d0d4f3ef4da720eb26a832199372c56d0956609ff07af750ee` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.split 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Context-only references	2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model Original source ↗ Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.split` Source artifact SHA-256: `54fe4db6f35c03d0d4f3ef4da720eb26a832199372c56d0956609ff07af750ee` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.subset No value recorded Context-only references	2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model Original source ↗ Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z	missing or unspecified No individual claim review recorded Audit details Field: `attributes.subset` Source artifact SHA-256: `54fe4db6f35c03d0d4f3ef4da720eb26a832199372c56d0956609ff07af750ee` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
description Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage. Context-only references	2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model Original source ↗ Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `54fe4db6f35c03d0d4f3ef4da720eb26a832199372c56d0956609ff07af750ee` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
name Human RNA 2OMe sites, independent test set Context-only references	2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model Original source ↗ Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z	not individually reviewed No individual claim review recorded Audit details Field: `name` Source artifact SHA-256: `54fe4db6f35c03d0d4f3ef4da720eb26a832199372c56d0956609ff07af750ee` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact

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Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Original source · journal full text in PMC

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Technical metadata and extraction receipts

Stable ID: paper-dataset-64b51e2f952f2c1c09

areas: rna-transcriptomes
tasks: human RNA 2-prime-O-methylation site prediction
split: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.
subset: Not reported
reported population: Not reported
source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
missing metadata: manifest: unextracted; scored count: unreported
entity classification: review date: 2026-09-17; rationale: This record identifies a biological data collection or source-labelled evaluation cohort. Keep its dataset identity; split, assay, taxonomic level, candidate restrictions and comparison context remain attributes rather than automatically becoming new entity kinds.; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC; ambiguities: None recorded

Related records

dataset: NmRF: Human RNA 2OMe sites, independent test set
dataset: Meta-2OM: Human RNA 2OMe sites, independent test set
dataset: 2OMe-LM: Human RNA 2OMe sites, independent test set
dataset: H2Opred: Human RNA 2OMe sites, independent test set
dataset: BERT2OME: Human RNA 2OMe sites, independent test set

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