COACH420, trained on CHEN11
Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage.
Dataset and evaluation context
A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.
Evaluation results
Release 2026-09-17-d277315f7d76 · 3 evaluations · 12 metric rows. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| CLAPE-SMB: COACH420, trained on CHEN11 Configuration: CLAPE-SMBProtocol: COACH420, trained on CHEN11 (protein-small molecule binding-site prediction)Dataset: COACH420, trained on CHEN11 Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.876 ± 0.002 AUROC Unit: unitless · Direction: higher | Uncertainty: printed: 0.002; value: 0.002; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 5: COACH420, trained on CHEN11 AUROC Source checking is not independent reproduction. |
| 0.395 ± 0.066 Recall Unit: unitless · Direction: higher | Uncertainty: printed: 0.066; value: 0.066; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Source checking is not independent reproduction. |
| 0.371 ± 0.009 MCC Unit: unitless · Direction: higher | Uncertainty: printed: 0.009; value: 0.009; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 4: COACH420, trained on CHEN11 MCC Source checking is not independent reproduction. |
| 0.412 ± 0.057 Precision Unit: unitless · Direction: higher | Uncertainty: printed: 0.057; value: 0.057; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 3: COACH420, trained on CHEN11 Precision Source checking is not independent reproduction. |
| P2Rank: COACH420, trained on CHEN11 Configuration: P2RankProtocol: COACH420, trained on CHEN11 (protein-small molecule binding-site prediction)Dataset: COACH420, trained on CHEN11 Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test. Result quoted from another source · Evaluation metadata: needs review | ||
| 0.079 Precision Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 2 P2Rank, column 3: COACH420, trained on CHEN11 Precision Source checking is not independent reproduction. |
| N/A AUROC Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 2 P2Rank, column 5: COACH420, trained on CHEN11 AUROC Source checking is not independent reproduction. |
| 0.888 Recall Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall Source checking is not independent reproduction. |
| 0.224 MCC Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 2 P2Rank, column 4: COACH420, trained on CHEN11 MCC Source checking is not independent reproduction. |
| GraphBind: COACH420, trained on CHEN11 Configuration: GraphBindProtocol: COACH420, trained on CHEN11 (protein-small molecule binding-site prediction)Dataset: COACH420, trained on CHEN11 Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test. Result quoted from another source · Evaluation metadata: needs review | ||
| 0.477 Recall Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall Source checking is not independent reproduction. |
| 0.889 AUROC Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 3 GraphBind, column 5: COACH420, trained on CHEN11 AUROC Source checking is not independent reproduction. |
| 0.303 MCC Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 3 GraphBind, column 4: COACH420, trained on CHEN11 MCC Source checking is not independent reproduction. |
| 0.223 Precision Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 3 GraphBind, column 3: COACH420, trained on CHEN11 Precision Source checking is not independent reproduction. |
Evidence table
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
6 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.reported_population No value recorded Context-only references | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record | missing or unspecified No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.source_locator Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Context-only references | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.split Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test. Context-only references | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.subset No value recorded Context-only references | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record | missing or unspecified No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| description Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage. Context-only references | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| name COACH420, trained on CHEN11 Context-only references | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
Release 2026-09-17-d277315f7d76 · Record review: needs review
- Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Original source · version of record
Technical metadata and extraction receipts
Stable ID: paper-dataset-d71026cdf5608821b0
- areas
- proteins-complexes
- tasks
- protein-small molecule binding-site prediction
- split
- Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test.
- subset
- Not reported
- reported population
- Not reported
- source locator
- Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall
- missing metadata
- manifest: unextracted; scored count: unreported
- entity classification
- review date: 2026-09-17; rationale: This record identifies a biological data collection or source-labelled evaluation cohort. Keep its dataset identity; split, assay, taxonomic level, candidate restrictions and comparison context remain attributes rather than automatically becoming new entity kinds.; source ids: clape-smb-2024; source locator: Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall; ambiguities: None recorded