Evaluation

CLAPE-SMB: COACH420, trained on CHEN11

Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test.

Evaluation procedure

Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test.

Configuration: CLAPE-SMB
Protocol: COACH420, trained on CHEN11 (protein-small molecule binding-site prediction)
Dataset: COACH420, trained on CHEN11

origin: Author-reported evaluation
configuration: Paper-specific predictor and its documented input information
protocol id: paper-protocol-efe21a629d215d8f9a
dataset version: Not reported
split: Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test.
subset: Not reported
population: Not reported
aggregation: Not reported
inputs: Not reported
adaptation: Paper-specific predictor and its documented input information
budget: Not reported
metric implementation: Not reported

Metadata review: needs review. Unreported conditions prevent automatic comparisons.

Evaluation results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 4 metric rows. Different protocols are not a single leaderboard.

Evaluation setupMetricEvidence origin

Results grouped by the exact reported evaluation
Metric and finding	Coverage and uncertainty	Evidence
CLAPE-SMB: COACH420, trained on CHEN11 Configuration: CLAPE-SMBProtocol: COACH420, trained on CHEN11 (protein-small molecule binding-site prediction)Dataset: COACH420, trained on CHEN11 Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test. Author-reported evaluation · Evaluation metadata: needs review
0.876 ± 0.002 AUROC Unit: unitless · Direction: higher	Uncertainty: printed: 0.002; value: 0.002; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported	source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 5: COACH420, trained on CHEN11 AUROC Source checking is not independent reproduction.
0.395 ± 0.066 Recall Unit: unitless · Direction: higher	Uncertainty: printed: 0.066; value: 0.066; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported	source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Source checking is not independent reproduction.
0.371 ± 0.009 MCC Unit: unitless · Direction: higher	Uncertainty: printed: 0.009; value: 0.009; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported	source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 4: COACH420, trained on CHEN11 MCC Source checking is not independent reproduction.
0.412 ± 0.057 Precision Unit: unitless · Direction: higher	Uncertainty: printed: 0.057; value: 0.057; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported	source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 2 (Tab2), row 4 CLAPE-SMB, column 3: COACH420, trained on CHEN11 Precision Source checking is not independent reproduction.

Evidence table

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

19 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statement	Original source and location	Review and provenance
attributes.comparison.adaptation Paper-specific predictor and its documented input information Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded author reported Audit details Field: `attributes.comparison.adaptation` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.aggregation No value recorded Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.aggregation` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.budget No value recorded Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.budget` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.dataset_version No value recorded Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.dataset_version` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.inputs No value recorded Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.inputs` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.metric_implementation No value recorded Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.metric_implementation` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.population No value recorded Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.population` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.protocol_id paper-protocol-efe21a629d215d8f9a Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded author reported Audit details Field: `attributes.comparison.protocol_id` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.split Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test. Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded author reported Audit details Field: `attributes.comparison.split` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.comparison.subset No value recorded Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall Version: version of record Retrieved: 2026-09-16T10:41:06Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.subset` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact

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Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Original source · version of record

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Technical metadata and extraction receipts

Stable ID: paper-evaluation-938fd2dbd8976c3862

areas: proteins-complexes
tasks: protein-small molecule binding-site prediction
origin: author_reported
protocol: Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test.
version: Paper-specific predictor and its documented input information
comparison: protocol id: paper-protocol-efe21a629d215d8f9a; dataset version: Not reported; split: Residue-level small-molecule binding-site classification. CHEN11 training, COACH420 test.; subset: Not reported; population: Not reported; aggregation: Not reported; inputs: Not reported; adaptation: Paper-specific predictor and its documented input information; budget: Not reported; metric implementation: Not reported
source locator: Comparison of CLAPE-SMB with other models trained on CHEN11 and tested on COACH420; Table 2 (Tab2), row 2 P2Rank, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 3 GraphBind, column 2: COACH420, trained on CHEN11 Recall; Table 2 (Tab2), row 4 CLAPE-SMB, column 2: COACH420, trained on CHEN11 Recall
missing metadata: checkpoint revision: unextracted; budget: unreported; split manifest: unextracted

Related records

model: CLAPE-SMB
benchmark: COACH420, trained on CHEN11 (protein-small molecule binding-site prediction)
dataset: COACH420, trained on CHEN11
evaluation: CLAPE-SMB: AUROC on COACH420, trained on CHEN11
evaluation: CLAPE-SMB: Recall on COACH420, trained on CHEN11
evaluation: CLAPE-SMB: MCC on COACH420, trained on CHEN11
evaluation: CLAPE-SMB: Precision on COACH420, trained on CHEN11

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