evaluation · needs review
structure-informed pLM: protein variant-effect classification
Evaluation procedure
combined amino-acid, secondary structure, solvent accessibility and contact-map scoring
- Model
- structure-informed pLM
- Benchmark
- protein variant-effect classification
- Dataset
- variant-effects benchmark
- origin
- Author-reported evaluation
- configuration
- not stated in table
- protocol id
- Not reported
- dataset version
- Not reported
- split
- paper evaluation
- population
- Not reported
- inputs
- Not reported
- adaptation
- Not reported
- metric implementation
- Not reported
- aggregation
- Not reported
- budget
- Not reported
Metadata review: needs review. Unreported conditions prevent automatic comparisons.
Evaluation results
Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| structure-informed pLM: protein variant-effect classification Model: structure-informed pLM · Benchmark: protein variant-effect classification · Dataset: variant-effects benchmark combined amino-acid, secondary structure, solvent accessibility and contact-map scoring Author-reported evaluation · Evaluation metadata: needs review | ||
| .803 AUROC Unit: fraction · Direction: unknown | Uncertainty: not reported in legacy extract Scored: Not reported · Eligible: Not reported | source checkedStructure-Informed Protein Language Models are Robust Predictors for Variant Effects · PMC12068927 HTML, Table4, AA+SS+RSA+CM row, AUROC column Source checking is not independent reproduction. |
Sources and history
Release 2026-09-16-d74d282221a9 · Record review: needs review
- Structure-Informed Protein Language Models are Robust Predictors for Variant Effects · Original source · Human Genetics 2025 journal article (online 2024)
Technical metadata and extraction receipts
Stable ID: evaluation-b2-structure-informed-plm-2025
- areas
- proteins-complexes
- tasks
- protein variant-effect classification
- origin
- author_reported
- protocol
- combined amino-acid, secondary structure, solvent accessibility and contact-map scoring
- version
- not stated in table
- comparison
- protocol id: Not reported; dataset version: Not reported; split: paper evaluation; population: Not reported; inputs: Not reported; adaptation: Not reported; metric implementation: Not reported; aggregation: Not reported; budget: Not reported
- missing metadata
- dataset version: not_reported_in_legacy_extract
Related records
- model: structure-informed pLM
- benchmark: protein variant-effect classification
- dataset: variant-effects benchmark
- evaluation: structure-informed pLM · AUROC · variant-effects benchmark