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Pipeline

ProteinBERT LLM-encoding model

This mRNA–protein interaction predictor uses ProteinBERT to encode RNA-binding-protein sequences.

SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Results and discussions/Limitations of sequence-based deep-learning models (paragraph 6); Datasets and methods (paragraph 1)

1 evaluation · 1 metric row

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. mRNA and RNA-binding-protein sequences. Then: 2. ProteinBERT LLM-encoding model. Then: 3. mRNA–protein interaction predictionsEvaluated procedure (conceptual)1. mRNA and RNA-binding-protein sequences. Then: 2. ProteinBERT LLM-encoding model. Then: 3. mRNA–protein interaction predictionsEvaluated procedure (conceptual)1. mRNA and RNA-binding-protein sequences. Then: 2. ProteinBERT LLM-encoding model. Then: 3. mRNA–protein interaction predictions

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)

At a glance

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
ProteinBERT LLM-encoding model: mRNA-protein interaction prediction

LLM encoding of protein partner; RBP-aware partition tests generalization to unseen protein diversity

Author-reported evaluation · Evaluation metadata: needs review

71.5% AUROC

Unit: percent · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Table 2, RBP-aware test set row, auROC (%) column

Source checking is not independent reproduction.

How it works

How the evaluated method works

ProteinBERT-derived protein features enter the paper’s attention-based mRNA–protein prediction framework alongside the RNA representation.

SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)
What was evaluated

The linked evaluation record identifies ProteinBERT LLM-encoding model: mRNA-protein interaction prediction. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-lit-b4-008

Strengths and limitations

Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-41ae49bb40ed8e

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeStudy-specific predictive method; this record is the paper-specific evaluated configuration.
SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)
Architecture / procedureProteinBERT-derived protein features enter the paper’s attention-based mRNA–protein prediction framework alongside the RNA representation.
SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)
Biological inputsmRNA and RNA-binding-protein sequences
SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Results and discussions/Limitations of sequence-based deep-learning models (paragraph 6); Datasets and methods/Evaluation metrics (paragraph 1)
OutputsmRNA–protein interaction predictions
SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Results and discussions/Limitations of sequence-based deep-learning models (paragraph 6); Results and discussions/Limitations of sequence-based deep-learning models (paragraph 5)
ParametersAn aggregate parameter total for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sources
Sources (2)Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity; cobisLab/mRPI-issue README.md · Datasets and methods; Datasets and methods/Preparation of the mRNA-protein interaction ground-truth dataset; Datasets and methods/The evaluated data partitioning schemes; Datasets and methods/The implemented RBP encoding schemes; Datasets and methods/The implemented RBP encoding schemes/One-hot encoding of RBPs and mRNA fragments; Datasets and methods/The implemented RBP encoding schemes/LLM-encoding of RBPs; Datasets and methods/The implemented RBP encoding schemes/Structure-aware encoding of RBPs; Datasets and methods/The modern attention-based deep network for mRPI identification; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision
Known versions / configurationProteinBERT LLM-encoding model is the comparison-table label; that label does not specify an immutable weight revision. · Not reported in inspected sources
SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingCLIP-derived interaction pairs with separate random-pair and RBP-aware partitions.
SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Datasets and methods (paragraph 1); Datasets and methods/The evaluated data partitioning schemes (paragraph 1)
Context limitsProtein inputs are padded to 2,804 residues and mRNA fragments to 1,024 nucleotides in the evaluated dataset.
SourcesGeneralizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity · Datasets and methods/The implemented RBP encoding schemes (paragraph 1); Datasets and methods/The implemented RBP encoding schemes/One-hot encoding of RBPs and mRNA fragments (paragraph 1)
AccessOfficial study implementation and usage documentation: https://github.com/cobisLab/mRPI-issue/blob/0f2d27666c4876f00d4c4e6cb3bec0e1629d214c/README.md. This pinned documentation revision is not automatically the evaluated weight revision.
SourcescobisLab/mRPI-issue README.md · README.md; installation, model download and usage instructions
Code licenceNo explicit code licence was established from the paper’s availability statement and inspected repository-root documentation. · Not reported in inspected sources
SourcescobisLab/mRPI-issue README.md · README.md and repository-root licence-file search
Weights licenceThe inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately. · Not reported in inspected sources
SourcescobisLab/mRPI-issue README.md · README.md; checkpoint/access documentation and licence scope

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

20 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["mRNA and RNA-binding-protein sequences","ProteinBERT LLM-encoding model","mRNA–protein interaction predictions"]

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Study-specific predictive method; this record is the paper-specific evaluated configuration.

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

ProteinBERT-derived protein features enter the paper’s attention-based mRNA–protein prediction framework alongside the RNA representation.

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

The inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately.

Individual claims
cobisLab/mRPI-issue README.md

Original source ↗

README.md; checkpoint/access documentation and licence scope

Version: 0f2d27666c4876f00d4c4e6cb3bec0e1629d214c
Retrieved: 2026-09-16T19:54:19.069409+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 10b6607fc40d285e20b681a7584b3e980265d15dcc79c3ac073aa4f030cfc141

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

mRNA and RNA-binding-protein sequences

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Results and discussions/Limitations of sequence-based deep-learning models (paragraph 6); Datasets and methods/Evaluation metrics (paragraph 1)

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

mRNA–protein interaction predictions

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Results and discussions/Limitations of sequence-based deep-learning models (paragraph 6); Results and discussions/Limitations of sequence-based deep-learning models (paragraph 5)

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources.

Individual claims
cobisLab/mRPI-issue README.md

Original source ↗

Datasets and methods; Datasets and methods/Preparation of the mRNA-protein interaction ground-truth dataset; Datasets and methods/The evaluated data partitioning schemes; Datasets and methods/The implemented RBP encoding schemes; Datasets and methods/The implemented RBP encoding schemes/One-hot encoding of RBPs and mRNA fragments; Datasets and methods/The implemented RBP encoding schemes/LLM-encoding of RBPs; Datasets and methods/The implemented RBP encoding schemes/Structure-aware encoding of RBPs; Datasets and methods/The modern attention-based deep network for mRPI identification; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 0f2d27666c4876f00d4c4e6cb3bec0e1629d214c
Retrieved: 2026-09-16T19:54:19.069409+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 10b6607fc40d285e20b681a7584b3e980265d15dcc79c3ac073aa4f030cfc141

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources.

Individual claims
Generalizable deep-learning-based mRNA-protein interaction prediction strongly depends on protein diversity

Original source ↗

Datasets and methods; Datasets and methods/Preparation of the mRNA-protein interaction ground-truth dataset; Datasets and methods/The evaluated data partitioning schemes; Datasets and methods/The implemented RBP encoding schemes; Datasets and methods/The implemented RBP encoding schemes/One-hot encoding of RBPs and mRNA fragments; Datasets and methods/The implemented RBP encoding schemes/LLM-encoding of RBPs; Datasets and methods/The implemented RBP encoding schemes/Structure-aware encoding of RBPs; Datasets and methods/The modern attention-based deep network for mRPI identification; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: version of record
Retrieved: 2026-09-16T10:33:57.257Z

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 94f9fe22a5f0e6c8619e4af994eb4f6ded7417efcf0c1240380269280f97f9d1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-41ae49bb40ed8e

areas
rna-transcriptomes
entity level
method
version
Not reported
reported name
ProteinBERT LLM-encoding model
historical missing metadata
version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This record identifies a composed analysis workflow with separately identifiable upstream models, representations or tools and a downstream prediction/scoring procedure. Results belong to that complete composition rather than to an upstream model alone.; source ids: mrna-protein-diversity-2026; source locator: Datasets and methods/The modern attention-based deep network for mRPI identification/Part 2: binding pattern integration (paragraph 1); Datasets and methods/The implemented RBP encoding schemes (paragraph 1) | Results and discussions/Limitations of sequence-based deep-learning models (paragraph 6); Datasets and methods (paragraph 1); ambiguities: This is the paper-specific pipeline identity; unspecified component checkpoints or implementation versions are not inferred from its name.
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