rewire.it
Pipeline

GSMFormer-PPI + ProstT5

GSMFormer-PPI combines molecular surfaces, structural graphs and ProstT5 sequence features for interaction prediction.

SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Results/Ablation experiments for input modalities (paragraph 1); Conclusions (paragraph 1)

1 evaluation · 1 metric row

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. Protein surface and 3D structure features plus ProstT5 sequence embeddings. Then: 2. GSMFormer-PPI + ProstT5. Then: 3. Protein–protein interaction predictionsEvaluated procedure (conceptual)1. Protein surface and 3D structure features plus ProstT5 sequence embeddings. Then: 2. GSMFormer-PPI + ProstT5. Then: 3. Protein–protein interaction predictionsEvaluated procedure (conceptual)1. Protein surface and 3D structure features plus ProstT5 sequence embeddings. Then: 2. GSMFormer-PPI + ProstT5. Then: 3. Protein–protein interaction predictions

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)

At a glance

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
GSMFormer-PPI + ProstT5: protein-protein interaction prediction

ProstT5 embeddings as graph node features

Author-reported evaluation · Evaluation metadata: needs review

0.988 AUROC

Unit: fraction · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedMultimodal graph, surface, and language-based model for protein protein interaction prediction · Table 6, ProstT5 embedding row, AUROC column

Source checking is not independent reproduction.

How it works

How the evaluated method works

MaSIF extracts physicochemical surface descriptors, graph convolutions process protein structure, and a transformer with linear projectors fuses these with residue-level embeddings.

SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)
What was evaluated

The linked evaluation record identifies GSMFormer-PPI + ProstT5: protein-protein interaction prediction. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-b2-gsmformer-ppi-2026

Strengths and limitations

Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-73ae07fb5be204

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeGraph-aware transformer pipeline; this record is the paper-specific evaluated configuration.
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)
Architecture / procedureMaSIF extracts physicochemical surface descriptors, graph convolutions process protein structure, and a transformer with linear projectors fuses these with residue-level embeddings.
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)
Biological inputsProtein surface and 3D structure features plus ProstT5 sequence embeddings
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Graph representation of 3D protein structure (paragraph 2); Discussion (paragraph 7)
OutputsProtein–protein interaction predictions
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Graph representation of 3D protein structure/Graph Convolutional Neural Network (GCN) (paragraph 1); Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2)
ParametersTable 3 reports 2.8M parameters for GSMFormer-PPI; the pretrained ProstT5 feature extractor is a separate component.
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Table3; GSMFormer-PPI row, Parameters column
Known versions / configurationGSMFormer-PPI + ProstT5 is the comparison-table label; that label does not specify an immutable weight revision. · Not reported in inspected sources
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingPINDER ML-ready splits with interface- and sequence-similarity controls, including the paper’s stated 30% sequence-identity threshold.
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Dataset/Splits (paragraph 1); Methods/Dataset/Splits (paragraph 2)
Context limitsCurated dimer chains contain 35–300 residues; embeddings are padded to the longest sequence in each batch.
SourcesMultimodal graph, surface, and language-based model for protein protein interaction prediction · Methods/Protein sequence feature extraction (paragraph 3); Methods/Graph representation of 3D protein structure/Graph Convolutional Neural Network (GCN) (paragraph 2)
AccessOfficial study implementation and usage documentation: https://github.com/ChervovNikita/gsmformer-ppi/blob/db9886e8b295f35b544a5703659e2a9115ce9e22/README.md. This pinned documentation revision is not automatically the evaluated weight revision.
SourcesChervovNikita/gsmformer-ppi README.md · README.md; installation, model download and usage instructions
Code licenceNo explicit code licence was established from the paper’s availability statement and inspected repository-root documentation. · Not reported in inspected sources
SourcesChervovNikita/gsmformer-ppi README.md · README.md and repository-root licence-file search
Weights licenceThe inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately. · Not reported in inspected sources
SourcesChervovNikita/gsmformer-ppi README.md · README.md; checkpoint/access documentation and licence scope

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

19 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Protein surface and 3D structure features plus ProstT5 sequence embeddings","GSMFormer-PPI + ProstT5","Protein–protein interaction predictions"]

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Graph-aware transformer pipeline; this record is the paper-specific evaluated configuration.

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

MaSIF extracts physicochemical surface descriptors, graph convolutions process protein structure, and a transformer with linear projectors fuses these with residue-level embeddings.

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

The inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately.

Individual claims
ChervovNikita/gsmformer-ppi README.md

Original source ↗

README.md; checkpoint/access documentation and licence scope

Version: db9886e8b295f35b544a5703659e2a9115ce9e22
Retrieved: 2026-09-16T19:54:16.546691+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 45003a18fbc137225141cc473b1399c47952183bf784cef8904d8ec3e298cf6b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

Protein surface and 3D structure features plus ProstT5 sequence embeddings

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Methods/Graph representation of 3D protein structure (paragraph 2); Discussion (paragraph 7)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

Protein–protein interaction predictions

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Methods/Graph representation of 3D protein structure/Graph Convolutional Neural Network (GCN) (paragraph 1); Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

Table 3 reports 2.8M parameters for GSMFormer-PPI; the pretrained ProstT5 feature extractor is a separate component.

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Table3; GSMFormer-PPI row, Parameters column

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Known versions / configuration

GSMFormer-PPI + ProstT5 is the comparison-table label; that label does not specify an immutable weight revision.

Individual claims
Multimodal graph, surface, and language-based model for protein protein interaction prediction

Original source ↗

Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558212+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: 9b364b5d73d16f2787f93f78f17dbe98b954ab9c2c64c1df960eec2e615eb3b4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-73ae07fb5be204

areas
proteins-complexes
entity level
method
version
not stated in table
reported name
GSMFormer-PPI + ProstT5
historical missing metadata
checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This record identifies a composed analysis workflow with separately identifiable upstream models, representations or tools and a downstream prediction/scoring procedure. Results belong to that complete composition rather than to an upstream model alone.; source ids: gsmformer-ppi-2026; source locator: Methods/Model architecture/Integration of protein structural and sequence features (paragraph 2); Methods/Model architecture/Linear projectors (paragraph 1) | Results/Ablation experiments for input modalities (paragraph 1); Conclusions (paragraph 1); ambiguities: This is the paper-specific pipeline identity; unspecified component checkpoints or implementation versions are not inferred from its name.
Related records

Suggest a correction