Strengths and considerations
No source-reviewed explanatory claims are recorded here yet.
SJC test split · Recall. Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences.
Explanatory profile: limited source coverage · Automated source review, 2026-09-17. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.
| Property | Description and evidence |
|---|---|
| Datasets | Not extracted or verified for this record. |
| Organisms | Not extracted or verified for this record. |
| Assays | Not extracted or verified for this record. |
| Splits | Not extracted or verified for this record. |
| Allowed inputs | Not extracted or verified for this record. |
| Adaptation | Not extracted or verified for this record. |
| Metrics | Not extracted or verified for this record. |
| Baselines | Not extracted or verified for this record. |
Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences.
Benchmarks bring together tasks and protocols. A task describes the biological question; a protocol defines a particular test.
These source-backed links do not make different protocols or scores interchangeable.
Each evaluation records what was tested and under which conditions.
Explore the results reported under one evaluation protocol. Each figure keeps its source, dataset and metric together; it is not a ranking across studies.
Recall (unitless) · Higher values are better for this metric.
Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences.
Source order is preserved. Plotted marks show point estimates; uncertainty, where reported, is retained in the printed values and table. Differences do not establish statistical significance.
Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Comparison of CLAPE-SMB with other models on the SJC; Table 3 (Tab3), row 2 P2Rank, column 2: SJC test split Recall; Table 3 (Tab3), row 3 GraphBind, column 2: SJC test split Recall; Table 3 (Tab3), row 4 DeepProSite, column 2: SJC test split Recall; Table 3 (Tab3), row 5 CLAPE-SMB, column 2: SJC test split Recall| Tested entity | Printed value | Uncertainty | Evidence |
|---|---|---|---|
| P2Rank · Configuration | 0.660 unitless | Not reported | Independent external evaluation · source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 2 P2Rank, column 2: SJC test split Recall |
| GraphBind · Configuration | 0.568 ± 0.024 unitless | printed: 0.024; value: 0.024; type: not explicitly identified in inspected table or caption | Independent external evaluation · source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 3 GraphBind, column 2: SJC test split Recall |
| DeepProSite · Configuration | 0.458 ± 0.022 unitless | printed: 0.022; value: 0.022; type: not explicitly identified in inspected table or caption | Independent external evaluation · source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 4 DeepProSite, column 2: SJC test split Recall |
| CLAPE-SMB · Configuration | 0.456 ± 0.006 unitless | printed: 0.006; value: 0.006; type: not explicitly identified in inspected table or caption | Author-reported evaluation · source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 5 CLAPE-SMB, column 2: SJC test split Recall |
Source transcription and grouping reviewed by automated source review on 2026-09-17. These experiments were not independently reproduced by rewire.
Release 2026-09-17-d277315f7d76 · 4 evaluations · 16 metric rows. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| CLAPE-SMB: SJC test split Configuration: CLAPE-SMBProtocol: SJC test split (protein-small molecule binding-site prediction)Dataset: SJC test split Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.651 ± 0.016 Precision Unit: unitless · Direction: higher | Uncertainty: printed: 0.016; value: 0.016; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 5 CLAPE-SMB, column 3: SJC test split Precision Source checking is not independent reproduction. |
| 0.529 ± 0.004 MCC Unit: unitless · Direction: higher | Uncertainty: printed: 0.004; value: 0.004; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 5 CLAPE-SMB, column 4: SJC test split MCC Source checking is not independent reproduction. |
| 0.915 ± 0.002 AUROC Unit: unitless · Direction: higher | Uncertainty: printed: 0.002; value: 0.002; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 5 CLAPE-SMB, column 5: SJC test split AUROC Source checking is not independent reproduction. |
| 0.456 ± 0.006 Recall Unit: unitless · Direction: higher | Uncertainty: printed: 0.006; value: 0.006; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 5 CLAPE-SMB, column 2: SJC test split Recall Source checking is not independent reproduction. |
| P2Rank: SJC test split Configuration: P2RankProtocol: SJC test split (protein-small molecule binding-site prediction)Dataset: SJC test split Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences. Independent external evaluation · Evaluation metadata: needs review | ||
| 0.660 Recall Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 2 P2Rank, column 2: SJC test split Recall Source checking is not independent reproduction. |
| 0.293 MCC Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 2 P2Rank, column 4: SJC test split MCC Source checking is not independent reproduction. |
| N/A AUROC Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 2 P2Rank, column 5: SJC test split AUROC Source checking is not independent reproduction. |
| 0.180 Precision Unit: unitless · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 2 P2Rank, column 3: SJC test split Precision Source checking is not independent reproduction. |
| GraphBind: SJC test split Configuration: GraphBindProtocol: SJC test split (protein-small molecule binding-site prediction)Dataset: SJC test split Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences. Independent external evaluation · Evaluation metadata: needs review | ||
| 0.486 ± 0.005 MCC Unit: unitless · Direction: higher | Uncertainty: printed: 0.005; value: 0.005; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 3 GraphBind, column 4: SJC test split MCC Source checking is not independent reproduction. |
| 0.906 ± 0.003 AUROC Unit: unitless · Direction: higher | Uncertainty: printed: 0.003; value: 0.003; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 3 GraphBind, column 5: SJC test split AUROC Source checking is not independent reproduction. |
| 0.568 ± 0.024 Recall Unit: unitless · Direction: higher | Uncertainty: printed: 0.024; value: 0.024; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 3 GraphBind, column 2: SJC test split Recall Source checking is not independent reproduction. |
| 0.462 ± 0.011 Precision Unit: unitless · Direction: higher | Uncertainty: printed: 0.011; value: 0.011; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 3 GraphBind, column 3: SJC test split Precision Source checking is not independent reproduction. |
| DeepProSite: SJC test split Configuration: DeepProSiteProtocol: SJC test split (protein-small molecule binding-site prediction)Dataset: SJC test split Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences. Independent external evaluation · Evaluation metadata: needs review | ||
| 0.458 ± 0.022 Recall Unit: unitless · Direction: higher | Uncertainty: printed: 0.022; value: 0.022; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 4 DeepProSite, column 2: SJC test split Recall Source checking is not independent reproduction. |
| 0.926 ± 0.002 AUROC Unit: unitless · Direction: higher | Uncertainty: printed: 0.002; value: 0.002; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 4 DeepProSite, column 5: SJC test split AUROC Source checking is not independent reproduction. |
| 0.524 ± 0.015 MCC Unit: unitless · Direction: higher | Uncertainty: printed: 0.015; value: 0.015; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 4 DeepProSite, column 4: SJC test split MCC Source checking is not independent reproduction. |
| 0.644 ± 0.011 Precision Unit: unitless · Direction: higher | Uncertainty: printed: 0.011; value: 0.011; type: not explicitly identified in inspected table or caption Scored: Not reported · Eligible: Not reported | source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 3 (Tab3), row 4 DeepProSite, column 3: SJC test split Precision Source checking is not independent reproduction. |
Last literature check: 2026-09-17. Dated primary-source discovery and protocol/table screening. Source checking does not mean experimental reproduction. Only separately extracted and independently reviewed numeric batches are publishable.
| Paper or primary resource | Version | Reference |
|---|---|---|
| Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning | version of record | Read source DOI: 10.1186/s13321-024-00920-2 |
complete tables extracted
No source-reviewed explanatory claims are recorded here yet.
No source-reviewed explanatory claims are recorded here yet.
Primary-source transcription and separate automated review. No human sign-off or experimental reproduction.
Stable record: paper-protocol-07cf559d2f1f9262e7Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
3 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Evaluation in this paper Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences. Individual claims | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models on the SJC; Table 3 (Tab3), row 2 P2Rank, column 2: SJC test split Recall; Table 3 (Tab3), row 3 GraphBind, column 2: SJC test split Recall; Table 3 (Tab3), row 4 DeepProSite, column 2: SJC test split Recall; Table 3 (Tab3), row 5 CLAPE-SMB, column 2: SJC test split Recall Version: version of record | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated review. No human sign-off or experimental reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Introduction SJC test split · Recall. Residue-level small-molecule binding-site classification. 80/10/10 train/validation/test partition of nonredundant sequences. Individual claims | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models on the SJC; Table 3 (Tab3), row 2 P2Rank, column 2: SJC test split Recall; Table 3 (Tab3), row 3 GraphBind, column 2: SJC test split Recall; Table 3 (Tab3), row 4 DeepProSite, column 2: SJC test split Recall; Table 3 (Tab3), row 5 CLAPE-SMB, column 2: SJC test split Recall Version: version of record | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated review. No human sign-off or experimental reproduction. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Relationship: evaluates task reported-task-b181ed450cdd41 Individual claims | Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Comparison of CLAPE-SMB with other models on the SJC; Table 3 (Tab3), row 2 P2Rank, column 2: SJC test split Recall; Table 3 (Tab3), row 3 GraphBind, column 2: SJC test split Recall; Table 3 (Tab3), row 4 DeepProSite, column 2: SJC test split Recall; Table 3 (Tab3), row 5 CLAPE-SMB, column 2: SJC test split Recall Version: version of record | source checked automated source review · 2026-09-17 Audit detailsField: Claim: paper-claim-419681a9f3306b9e0e Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-09-17-d277315f7d76 · Record review: needs review
Stable ID: paper-protocol-07cf559d2f1f9262e7