0.731911 tissue_weighted_mean_auprc
Pangolin (paper Table 4): Splicing-QTL causality, tissue weighted mean auprc
- Tested model
- Pangolin (paper Table 4)
- Task or benchmark
- Splicing-QTL causality (AlphaGenome paper)
- Dataset
- Splicing-QTL causality: evaluated data subset
- Procedure
- Compare predicted splicing effects for causal sQTLs and matched negatives; keep the wide and proximal splice-distance analyses distinct.
- Evaluation
- Pangolin (paper Table 4): Splicing-QTL causality
- Evidence
- Author-reported evaluation · source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 4 Variant performan'!L5
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.
Evaluation results
Release 2026-09-17-a757f4af4277 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| Pangolin (paper Table 4): Splicing-QTL causality Model: Pangolin (paper Table 4) · Benchmark: Splicing-QTL causality (AlphaGenome paper) · Dataset: Splicing-QTL causality: evaluated data subset Compare predicted splicing effects for causal sQTLs and matched negatives; keep the wide and proximal splice-distance analyses distinct. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.731911 tissue_weighted_mean_auprc Unit: dimensionless · Direction: higher Aggregation: auPRC per tissue, averaged with variant-count weights. | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 4 Variant performan'!L5 Source checking is not independent reproduction. |
Evidence table
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 0.731911 Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 4 Variant performan'!L5 Version: Nature version of record, 28 January 2026 | source checked OOXML extraction and separate automated primary-source review · 2026-09-17 author reported Audit detailsChecked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx Extraction artifact SHA-256: |
Sources and history
Release 2026-09-17-a757f4af4277 · Record review: source checked
- AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
- AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
- alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied
Technical metadata and extraction receipts
Stable ID: alphagenome-2026-result-7dc9469b682e5fda
- areas
- dna-genomes
- printed value
- 0.731911
- printed value basis
- Canonical stored-number transcription of a General-format cell; visible spreadsheet precision depends on column width.
- numeric value
- 0.73191099999999998
- raw xml value
- 0.73191099999999998
- workbook number format
- General
- metric
- tissue_weighted_mean_auprc
- metric direction
- higher
- unit
- dimensionless
- aggregation
- auPRC per tissue, averaged with variant-count weights.
- uncertainty
- Not reported
- scored count
- Not reported
- eligible count
- Not reported
- source cells
- 'Suppl Table 4 Variant performan'!L5
- source locator
- 'Suppl Table 4 Variant performan'!L5
- review
- method: OOXML extraction and separate automated primary-source review; date: 2026-09-17; artifact sha256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154; retrieval url: https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41586-025-10014-0/MediaObjects/41586_2025_10014_MOESM3_ESM.xlsx; note: Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun.
- missing metadata
- uncertainty: unreported; scored count: unextracted; eligible count: unextracted; seeds: unreported
- source warnings
- None recorded
Related records
- evaluation: Pangolin (paper Table 4): Splicing-QTL causality