result · source checked

0.79 auPRC

AlphaGenome ensemble of four fold-1 models: Human splice-site classification: RNA-derived, auPRC

Tested model: AlphaGenome ensemble of four fold-1 models
Model family: AlphaGenome
Task or benchmark: Human splice-site classification: RNA-derived (AlphaGenome paper)
Dataset: Human splice-site classification: RNA-derived: evaluated data subset
Procedure: Compare probabilities with the selected binary splice-site labels at genomic positions.
Evaluation: AlphaGenome ensemble of four fold-1 models: Human splice-site classification: RNA-derived
Evidence: Author-reported evaluation · source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K2; 'Suppl Table 3 Track performance'!K3

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Evaluation results

Release 2026-09-17-a757f4af4277 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Evaluated configurationMetricEvidence origin

Results grouped by the exact reported evaluation
Metric and finding	Coverage and uncertainty	Evidence
AlphaGenome ensemble of four fold-1 models: Human splice-site classification: RNA-derived Model: AlphaGenome ensemble of four fold-1 models · Benchmark: Human splice-site classification: RNA-derived (AlphaGenome paper) · Dataset: Human splice-site classification: RNA-derived: evaluated data subset Compare probabilities with the selected binary splice-site labels at genomic positions. Author-reported evaluation · Evaluation metadata: needs review
0.79 auPRC Unit: dimensionless · Direction: higher Aggregation: Compute auPRC separately for four strand/site classes and average the four values.	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K2; 'Suppl Table 3 Track performance'!K3 Source checking is not independent reproduction.

Evidence table

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-a757f4af4277
Property and statement	Original source and location	Review and provenance
Reported result 0.79 Individual claims	AlphaGenome Nature 2026 supplementary comparison tables Original source ↗ 'Suppl Table 3 Track performance'!K2; 'Suppl Table 3 Track performance'!K3 Version: Nature version of record, 28 January 2026 Retrieved: 2026-09-17T06:31:06.887921+00:00	source checked OOXML extraction and separate automated primary-source review · 2026-09-17 author reported Audit details Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun. Field: `attributes.printed_value` Source artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx Inspected artifact Extraction artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Extraction artifact

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Sources and history

Release 2026-09-17-a757f4af4277 · Record review: source checked

AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied

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Technical metadata and extraction receipts

Stable ID: alphagenome-2026-result-8b641d8fe5b30f89

areas: dna-genomes
printed value: 0.79
printed value basis: Workbook number format 0.00
numeric value: 0.79100000000000004
raw xml value: 0.79100000000000004
workbook number format: 0.00
metric: auPRC
metric direction: higher
unit: dimensionless
aggregation: Compute auPRC separately for four strand/site classes and average the four values.
uncertainty: Not reported
scored count: Not reported
eligible count: Not reported
source cells: 'Suppl Table 3 Track performance'!K2; 'Suppl Table 3 Track performance'!K3
source locator: 'Suppl Table 3 Track performance'!K2; 'Suppl Table 3 Track performance'!K3
review: method: OOXML extraction and separate automated primary-source review; date: 2026-09-17; artifact sha256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154; retrieval url: https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41586-025-10014-0/MediaObjects/41586_2025_10014_MOESM3_ESM.xlsx; note: Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun.
missing metadata: uncertainty: unreported; scored count: unextracted; eligible count: unextracted; seeds: unreported
source warnings: None recorded

Related records

evaluation: AlphaGenome ensemble of four fold-1 models: Human splice-site classification: RNA-derived

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