0.46 profile jsd
AlphaGenome fold-0 track model on comparator-matched test peaks: ATAC prediction on held-out peaks, profile jsd
- Tested model
- AlphaGenome fold-0 track model on comparator-matched test peaks
- Model family
- AlphaGenome
- Task or benchmark
- ATAC prediction on held-out peaks (AlphaGenome paper)
- Dataset
- ATAC prediction on held-out peaks: evaluated data subset
- Procedure
- Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3.
- Evaluation
- AlphaGenome fold-0 track model on comparator-matched test peaks: ATAC prediction on held-out peaks
- Evidence
- Author-reported evaluation · source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K30
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.
Evaluation results
Release 2026-09-17-a757f4af4277 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| AlphaGenome fold-0 track model on comparator-matched test peaks: ATAC prediction on held-out peaks Model: AlphaGenome fold-0 track model on comparator-matched test peaks · Benchmark: ATAC prediction on held-out peaks (AlphaGenome paper) · Dataset: ATAC prediction on held-out peaks: evaluated data subset Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.46 profile jsd Unit: dimensionless · Direction: lower Aggregation: Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines. | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K30 Source checking is not independent reproduction. |
Evidence table
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 0.46 Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 3 Track performance'!K30 Version: Nature version of record, 28 January 2026 | source checked OOXML extraction and separate automated primary-source review · 2026-09-17 author reported Audit detailsChecked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx Extraction artifact SHA-256: |
Sources and history
Release 2026-09-17-a757f4af4277 · Record review: source checked
- AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
- AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
- alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied
Technical metadata and extraction receipts
Stable ID: alphagenome-2026-result-c858347ce602e204
- areas
- dna-genomes
- printed value
- 0.46
- printed value basis
- Workbook number format 0.00
- numeric value
- 0.45979900000000001
- raw xml value
- 0.45979900000000001
- workbook number format
- 0.00
- metric
- profile jsd
- metric direction
- lower
- unit
- dimensionless
- aggregation
- Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.
- uncertainty
- Not reported
- scored count
- Not reported
- eligible count
- Not reported
- source cells
- 'Suppl Table 3 Track performance'!K30
- source locator
- 'Suppl Table 3 Track performance'!K30
- review
- method: OOXML extraction and separate automated primary-source review; date: 2026-09-17; artifact sha256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154; retrieval url: https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41586-025-10014-0/MediaObjects/41586_2025_10014_MOESM3_ESM.xlsx; note: Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun.
- missing metadata
- uncertainty: unreported; scored count: unextracted; eligible count: unextracted; seeds: unreported
- source warnings
- Main Fig.1 calls JSD Jensen–Shannon divergence; Extended Data Fig.3 calls it distance. Preserve the printed JSD label; implementation-level squared/root equivalence is not established here.