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result · source checked

0.948 AUC

MegSite + ESM3 · AUC · DNA-129_Test

Tested model
MegSite + ESM3
Task or benchmark
DNA-binding residue prediction
Dataset
DNA-129_Test
Procedure
ESM3 multimodal embedding ablation in MegSite
Evaluation
MegSite + ESM3: DNA-binding residue prediction
Evidence
Author-reported evaluation · source checkedMegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model · Table 2, DNA-129_Test / ESM3 row, AUC column

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Evaluation results

Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
MegSite + ESM3: DNA-binding residue prediction

ESM3 multimodal embedding ablation in MegSite

Author-reported evaluation · Evaluation metadata: needs review

0.948 AUC

Unit: fraction · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedMegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model · Table 2, DNA-129_Test / ESM3 row, AUC column

Source checking is not independent reproduction.

Sources and history

Release 2026-09-16-d74d282221a9 · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: b2-megsite-2025

areas
proteins-complexes
tasks
DNA-binding residue prediction
printed value
0.948
numeric value
0.948
metric
AUC
metric direction
unknown
unit
fraction
uncertainty
Not reported
source locator
Table 2, DNA-129_Test / ESM3 row, AUC column
review
method: independent_ai_table_review; reviewer: Codex secondary table review; reviewed at: 2026-09-16T10:38:57.558213+00:00; notes: Resolved DNA-129_Test row group and ESM3 row. AUC is 0.948; the next numeric cell 0.582 is AP. Caption states an embedding comparison within MegSite.; evidence: Original PMC XML table headers, row groups and caption inspected; printed value 0.948.; artifact sha256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12496013/fullTextXML
legacy id
b2-megsite-2025
legacy row
id: b2-megsite-2025; paper id: megsite-2025; domain id: proteins-complexes; task: DNA-binding residue prediction; model: MegSite + ESM3; model version: not stated in table; dataset: DNA-129_Test; dataset version: Not reported; split: independent test; metric: AUC; value: 0.948; unit: fraction; uncertainty: Not reported; protocol: ESM3 multimodal embedding ablation in MegSite; source locator: Table 2, DNA-129_Test / ESM3 row, AUC column; source url: https://pmc.ncbi.nlm.nih.gov/articles/PMC12496013/; evaluation origin: author_reported; reviewed utc: 2026-09-15T23:33:26Z
missing metadata
dataset version: not_reported_in_legacy_extract; uncertainty: not_reported_in_legacy_extract
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