rewire.it
result · source checked

0.917 AUROC

CLAPE-SMB with ESM-2 · AUROC · SJC

Tested model
CLAPE-SMB with ESM-2
Task or benchmark
protein-small molecule binding-site prediction
Dataset
SJC
Procedure
Contrastive CLAPE-SMB binding-site predictor with ESM-2 feature extractor
Evaluation
CLAPE-SMB with ESM-2: protein-small molecule binding-site prediction
Evidence
Author-reported evaluation · source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 5, ESM-2 / SJC row, AUROC column

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Evaluation results

Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
CLAPE-SMB with ESM-2: protein-small molecule binding-site prediction

Contrastive CLAPE-SMB binding-site predictor with ESM-2 feature extractor

Author-reported evaluation · Evaluation metadata: needs review

0.917 AUROC

Unit: fraction · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedProtein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Table 5, ESM-2 / SJC row, AUROC column

Source checking is not independent reproduction.

Sources and history

Release 2026-09-16-d74d282221a9 · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: lit-b4-011

areas
proteins-complexes
tasks
protein-small molecule binding-site prediction
printed value
0.917
numeric value
0.917
metric
AUROC
metric direction
unknown
unit
fraction
uncertainty
Not reported
source locator
Table 5, ESM-2 / SJC row, AUROC column
review
method: independent_ai_table_review; reviewer: Codex primary curator table review; reviewed at: 2026-09-16T10:41:06Z; notes: ESM-2 on SJC AUROC. Transcription verified; experimental claims not independently reproduced.; evidence: 0.917; artifact sha256: 215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11542454/fullTextXML
legacy id
lit-b4-011
legacy row
id: lit-b4-011; paper id: clape-smb-2024; domain id: proteins-complexes; task: protein-small molecule binding-site prediction; model: CLAPE-SMB with ESM-2; model version: Not reported; dataset: SJC; dataset version: Not reported; split: Not reported; metric: AUROC; value: 0.917; unit: fraction; uncertainty: Not reported; protocol: Contrastive CLAPE-SMB binding-site predictor with ESM-2 feature extractor; source locator: Table 5, ESM-2 / SJC row, AUROC column; source url: https://pmc.ncbi.nlm.nih.gov/articles/PMC11542454/; evaluation origin: author_reported; reviewed utc: 2026-09-15T23:37:05Z
missing metadata
model version: not_reported_in_legacy_extract; dataset version: not_reported_in_legacy_extract; split: not_reported_in_legacy_extract; uncertainty: not_reported_in_legacy_extract
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