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ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error

Ligand binding affinity, root mean squared error. Scored with RMSE on ATOM3D LBA. Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.

5 evaluations · 5 metric rows

Overview

Ligand binding affinity, root mean squared error. Scored with RMSE on ATOM3D LBA. Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluation design

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Benchmarks

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Recorded evaluations

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Run instructions

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Published comparisons

Explore the results reported under one evaluation protocol. Each figure keeps its source, dataset and metric together; it is not a ranking across studies. The pooled view gathers every source table that reports the same metric and names what it does not hold constant.

ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error

rmse (error) · Lower values are better for this metric.

Every method ATOM3D reports on Ligand binding affinity, root mean squared error, scored with RMSE on ATOM3D LBA.

Evaluation protocol · ATOM3D LBA (ATOM3D split)

  1. 3DCNN · Method · Author-reported evaluation1.416
  2. GNN · Method · Author-reported evaluation1.601
  3. ENN · Method · Author-reported evaluation1.568
  4. [Öztürk et al., 2018] · Configuration · Author-reported evaluation1.565
  5. [Karimi et al., 2019] · Configuration · Author-reported evaluation1.893

Source order is preserved. Plotted marks show point estimates; uncertainty, where reported, is retained in the printed values and table. Differences do not establish statistical significance.

ATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE)
Values, uncertainty and evidence
rmse: original source values
Tested entityPrinted valueUncertaintyEvidence
3DCNN · Method1.416 errorNot reportedAuthor-reported evaluation · source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column(3DCNN)
GNN · Method1.601 errorNot reportedAuthor-reported evaluation · source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column(GNN)
ENN · Method1.568 errorNot reportedAuthor-reported evaluation · source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column(ENN)
[Öztürk et al., 2018] · Configuration1.565 errorNot reportedAuthor-reported evaluation · source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column([Öztürk et al., 2018])
[Karimi et al., 2019] · Configuration1.893 errorNot reportedAuthor-reported evaluation · source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column([Karimi et al., 2019])
Scope and limitations
  • Author-reported numbers, source checked but not independently reproduced.
  • MAE and RMSE are errors, better when lower. The other metrics are better when higher.
  • Comparison methods are named by the citation the table prints; the paper's text says which method each is.
  • The paper marks some runs with an asterisk to say their training data differed, though the splitting criteria were the same.

Source transcription and grouping reviewed by automated source review on 2026-09-18. These experiments were not independently reproduced by rewire.

Tested entities and results

Release 2026-09-17-134cd1815de8 · 5 evaluations · 5 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
3DCNN on ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error

Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.

Author-reported evaluation · Evaluation metadata: source checked

1.416 rmse

Unit: error · Direction: lower

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column(3DCNN)

Source checking is not independent reproduction.

ENN on ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error

Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.

Author-reported evaluation · Evaluation metadata: source checked

1.568 rmse

Unit: error · Direction: lower

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column(ENN)

Source checking is not independent reproduction.

GNN on ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error

Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.

Author-reported evaluation · Evaluation metadata: source checked

1.601 rmse

Unit: error · Direction: lower

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column(GNN)

Source checking is not independent reproduction.

[Karimi et al., 2019] on ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error

Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.

Author-reported evaluation · Evaluation metadata: source checked

1.893 rmse

Unit: error · Direction: lower

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column([Karimi et al., 2019])

Source checking is not independent reproduction.

[Öztürk et al., 2018] on ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error

Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.

Author-reported evaluation · Evaluation metadata: source checked

1.565 rmse

Unit: error · Direction: lower

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedATOM3D: Tasks On Molecules in Three Dimensions · Table 5, row(LBA RMSE), column([Öztürk et al., 2018])

Source checking is not independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-134cd1815de8
Property and statementOriginal source and locationReview and provenance
Relationship: part of

discovery-benchmark-atom3d

Individual claims
ATOM3D: Tasks On Molecules in Three Dimensions

Original source ↗

Table 5, row(LBA RMSE)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.182997+00:00

source checked

automated source review · 2026-09-18

Audit details

Primary-source transcription with no human sign-off and no independent reproduction.

Field: links:part_of:discovery-benchmark-atom3d

Claim: atom3d-association-lba-rmse

Source artifact SHA-256: 92656c20a15311c32bed9edc7f465bb26eb30338f40324fe43bec4b1fc6a7890

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

Release 2026-09-17-134cd1815de8 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: atom3d-task-lba-rmse

areas
molecular-interactions
tasks
Ligand binding affinity, root mean squared error
metric
RMSE
metric direction
lower
dataset
ATOM3D LBA
protocol
Trained and scored under the ATOM3D split for this task. Asterisks in the paper mark a run whose training data differed.
source locator
Table 5, row(LBA RMSE)
comparison panels
id: atom3d-panel-lba-rmse; title: ATOM3D LBA-RMSE: Ligand binding affinity, root mean squared error; protocol id: atom3d-task-lba-rmse; dataset id: atom3d-dataset-atom3d-lba; metric: rmse; unit: error; direction: lower; result ids: atom3d-result-3dcnn-lba-rmse-rmse; atom3d-result-gnn-lba-rmse-rmse; atom3d-result-enn-lba-rmse-rmse; atom3d-result-zt-rk-et-al-2018-lba-rmse-rmse; atom3d-result-karimi-et-al-2019-lba-rmse-rmse; source ids: evidence-expansion-atom3d-92656c20; source locator: Table 5, row(LBA RMSE); context: Every method ATOM3D reports on Ligand binding affinity, root mean squared error, scored with RMSE on ATOM3D LBA.; caveats: Author-reported numbers, source checked but not independently reproduced.; MAE and RMSE are errors, better when lower. The other metrics are better when higher.; Comparison methods are named by the citation the table prints; the paper's text says which method each is.; The paper marks some runs with an asterisk to say their training data differed, though the splitting criteria were the same.; review: method: automated_source_review; date: 2026-09-18
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