rewire.it
Task

RNA secondary-structure prediction

RNA secondary-structure prediction uses a specified bpRNA benchmark version while distinguishing pretraining from supervised task data.

SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

1 evaluation · 1 metric row

At a glance

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Data, procedure and scoring
PropertyDescription and evidence
DatasetsbpRNA-1m similarity-filtered variants; the main task uses the standard TR0/VL0/TS0 benchmark.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
SplitsTR0 is used for task training, VL0 for validation and TS0 for testing.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
MetricsBase-pairing F1 is used for secondary-structure model selection and evaluation; contact-map post-processing is shared across methods.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
BaselinesThe partition is aligned with UFold and RNA-FM comparisons; UNI-RNA uses additional task-training data.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
Leakage controlsThe bpRNA benchmark variants apply explicit sequence-similarity filtering, including the 80% variant used for TR0/VL0/TS0. The cited dataset Methods do not give a cross-corpus exclusion audit against RNAcentral pretraining.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset and RNA secondary structure dataset; cached paragraphs 71–72,84–87
UncertaintyThe cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim. · Not reported in inspected sources
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
Entity typePaper-specific computational evaluation protocol.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
OrganismsThe secondary-structure task is defined by bpRNA sequences and RNA-family collections. Its downstream-dataset Methods describe similarity filtering and partition membership, but do not tabulate the evaluated sequences by organism. · Not reported in inspected sources
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: RNA secondary structure datasets; bpRNA-1m and ArchiveII
AssaysReference RNA secondary structures.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
Allowed inputsRNA sequence.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
AdaptationSupervised structure-task training on TR0, validation on VL0 and testing on TS0.
SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

How it works

How it worksComputational evaluation flow
Computational evaluation flow1. Input: RNA sequence.. Then: 2. Evaluation: Supervised structure-task training on TR0, validation on VL0 and testing on TS0.. Then: 3. Readout: Base-pairing F1 is used for secondary-structure model selection and evaluation; contact-map post-processing is shared across methods.Computational evaluation flow1. Input: RNA sequence.. Then: 2. Evaluation: Supervised structure-task training on TR0, validation on VL0 and testing on TS0.. Then: 3. Readout: Base-pairing F1 is used for secondary-structure model selection and evaluation; contact-map post-processing is shared across methods.Computational evaluation flow1. Input: RNA sequence.. Then: 2. Evaluation: Supervised structure-task training on TR0, validation on VL0 and testing on TS0.. Then: 3. Readout: Base-pairing F1 is used for secondary-structure model selection and evaluation; contact-map post-processing is shared across methods.

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
Evaluation methodology

bpRNA-1m similarity-filtered variants; the main task uses the standard TR0/VL0/TS0 benchmark. Base-pairing F1 is used for secondary-structure model selection and evaluation; contact-map post-processing is shared across methods. The partition is aligned with UFold and RNA-FM comparisons; UNI-RNA uses additional task-training data.

SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table; Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table; Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Tested entities and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
ERNIE-RNA: RNA secondary-structure prediction

zero-shot attention-derived base-pair prediction

Author-reported evaluation · Evaluation metadata: needs review

0.575 binary F1

Unit: fraction · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedERNIE-RNA: an RNA language model with structure-enhanced representations · Table 2, ERNIE-RNA zero-shot row, bpRNA-new F1-Score (binary) column

Source checking is not independent reproduction.

Papers and result coverage

Last literature check: 2026-09-17. Dated primary-source discovery and protocol/table screening. Source checking does not mean experimental reproduction. Only separately extracted and independently reviewed numeric batches are publishable.

Paper or primary resourceVersionReference
ERNIE-RNA: an RNA language model with structure-enhanced representationsjournal full text in PMCRead source

What is still missing

  • complete numerical transcription and independent cell review: Full primary artifact and table inventory preserved; no new numeric row is published from this audit alone.
  • exact checkpoint hashes and per-method scored denominators: Table labels alone do not establish these fields; do not infer checkpoint or scored count from model name or dataset size.
Search and extraction details

primary comparison tables located

Searches

  • ERNIE-RNA: an RNA language model with structure-enhanced representations 10.1038/s41467-025-64972-0

Evidence locations

  • Table 1; XML table Tab1
  • Table 2; XML table Tab2

Strengths and limitations

Strengths and considerations

No source-reviewed explanatory claims are recorded here yet.

Limitations and conditions

  • The different bpRNA similarity-filtered variants have different sequence memberships. Reporting a dataset family name alone is insufficient to identify the evaluated split.
    SourcesERNIE-RNA: an RNA language model with structure-enhanced representations · Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table
Profile review details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Stable record: reported-task-a2bf7ddbc71d23

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

17 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Input: RNA sequence.","Evaluation: Supervised structure-task training on TR0, validation on VL0 and testing on TS0.","Readout: Base-pairing F1 is used for secondary-structure model selection and evaluation; contact-map post-processing is shared across methods."]

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Computational evaluation flow

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.title

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Datasets

bpRNA-1m similarity-filtered variants; the main task uses the standard TR0/VL0/TS0 benchmark.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Splits

TR0 is used for task training, VL0 for validation and TS0 for testing.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Adaptation

Supervised structure-task training on TR0, validation on VL0 and testing on TS0.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Metrics

Base-pairing F1 is used for secondary-structure model selection and evaluation; contact-map post-processing is shared across methods.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Baselines

The partition is aligned with UFold and RNA-FM comparisons; UNI-RNA uses additional task-training data.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Leakage controls

The bpRNA benchmark variants apply explicit sequence-similarity filtering, including the 80% variant used for TR0/VL0/TS0. The cited dataset Methods do not give a cross-corpus exclusion audit against RNAcentral pretraining.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset and RNA secondary structure dataset; cached paragraphs 71–72,84–87

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Uncertainty

The cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim.

Individual claims
ERNIE-RNA: an RNA language model with structure-enhanced representations

Original source ↗

Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558206+00:00

unreported

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: 0bd1d4b3cbf5d59d452cec4864614947861efcee050ba07e7de395cd90630047

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-task-a2bf7ddbc71d23

areas
rna-transcriptomes
tasks
RNA secondary-structure prediction
entity level
task
version
Not reported
task
RNA secondary-structure prediction
scope note
Paper-specific evaluation task; protocol completeness requires further extraction.
benchmark research
review date: 2026-09-17; status: primary_comparison_tables_located; primary sources: evidence-expansion-ernie-rna-2025-0bd1d4b3; inspected locators: Table 1; XML table Tab1; Table 2; XML table Tab2; searched queries: ERNIE-RNA: an RNA language model with structure-enhanced representations 10.1038/s41467-025-64972-0; gaps: complete numerical transcription and independent cell review: Full primary artifact and table inventory preserved; no new numeric row is published from this audit alone.; exact checkpoint hashes and per-method scored denominators: Table labels alone do not establish these fields; do not infer checkpoint or scored count from model name or dataset size.; claim scope: Dated primary-source discovery and protocol/table screening. Source checking does not mean experimental reproduction. Only separately extracted and independently reviewed numeric batches are publishable.
historical missing metadata
protocol version: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
benchmark
entity classification
review date: 2026-09-17; rationale: This source-scoped record identifies the biological prediction task and holds its paper context. Preserve the existing task identity; exact split, model adaptation and scoring remain in linked evaluations or separate protocol records.; source ids: ernie-rna-2025; source locator: Methods: Training dataset; RNA secondary structure dataset; cached text lines 71–72, 84–87; task metric definitions and corresponding results table; ambiguities: A paper- or suite-specific task may constrain some inputs or metrics; that alone does not make it interchangeable with a complete versioned protocol. No protocol equivalence is inferred.; Some legacy profile Entity type facts use the generic phrase computational evaluation protocol. That boilerplate is not sufficient to establish a single fixed protocol identity or to merge this task with another protocol record.
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