rewire.it
Task

pathogen detection

The source reports a separate metagenomic taxon-detection comparison, but its executable evaluation protocol remains incomplete.

SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

1 evaluation · 1 metric row

At a glance

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Data, procedure and scoring
PropertyDescription and evidence
DatasetsMetaHIT and iHMP shotgun-sequencing cohorts; the source describes expert annotations or high-confidence reference calls as ground truth without resolving their construction here.
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
SplitsThe genomic experiment in §4.3 does not specify a sample/split manifest. The five-fold procedure in §4.2 concerns other datasets and cannot supply this missing genomic protocol. · Not reported in inspected sources
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
MetricsPrecision, recall, F1 and ROC-AUC for the genomic comparison.
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
BaselinesKraken2 and MetaPhlAn3.
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
Leakage controlsThe genomic experiment in §4.3 does not establish independence of the expert/reference-derived labels from the compared prediction systems. · Not reported in inspected sources
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
UncertaintyMetaHIT/iHMP Table 3 gives point precision, recall, F1 and AUC values without a replicate count or confidence-interval procedure. The ± values and five-fold evaluation elsewhere concern other datasets and cannot supply uncertainty for this sequencing comparison. · Not reported in inspected sources
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · §4.3, MetaHIT/iHMP experiment paragraph and Table 3; contrast §4.2 and Table 2
Entity typePaper-specific computational evaluation protocol.
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
OrganismsHuman-cohort microbial communities in MetaHIT and iHMP.
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
AssaysShotgun sequencing; expert/reference-derived labels whose construction remains insufficiently specified.
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
Allowed inputsMetagenomic sequencing data and model-specific representations.
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
AdaptationSection 4.3 says the model is applied directly to preprocessed sequencing reads but does not specify its genomic fitting partition, checkpoint or whether MetaHIT/iHMP labels were available during fitting. The five-fold setup in §4.2 is attached to other datasets. · Not reported in inspected sources
SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · §4.2–4.3, genomic sequencing experiment immediately preceding Table 3

How it works

How it worksComputational evaluation flow
Computational evaluation flow1. Input: Metagenomic sequencing data and model-specific representations.. Then: 2. Task: The source reports a separate metagenomic taxon-detection comparison, but its executable evaluation protocol remains incomplete.Computational evaluation flow1. Input: Metagenomic sequencing data and model-specific representations.. Then: 2. Task: The source reports a separate metagenomic taxon-detection comparison, but its executable evaluation protocol remains incomplete.Computational evaluation flow1. Input: Metagenomic sequencing data and model-specific representations.. Then: 2. Task: The source reports a separate metagenomic taxon-detection comparison, but its executable evaluation protocol remains incomplete.

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
Evaluation methodology

MetaHIT and iHMP shotgun-sequencing cohorts; the source describes expert annotations or high-confidence reference calls as ground truth without resolving their construction here. The genomic experiment in §4.3 does not specify a sample/split manifest. The five-fold procedure in §4.2 concerns other datasets and cannot supply this missing genomic protocol. Precision, recall, F1 and ROC-AUC for the genomic comparison. Kraken2 and MetaPhlAn3. The genomic experiment in §4.3 does not establish independence of the expert/reference-derived labels from the compared prediction systems.

SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Tested entities and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
TCINet + HTRS: pathogen detection

Taxonomy-constrained inference network with hierarchical taxonomy representation

Author-reported evaluation · Evaluation metadata: needs review

0.84 F1

Unit: fraction · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedEnhancing pathogen identification through AI-assisted metagenomic sequencing · Table 3, MetaHIT dataset section, TCINet + HTRS (Ours) row, F1-score column

Source checking is not independent reproduction.

Papers and result coverage

Last literature check: 2026-09-17. Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.

Paper or primary resourceVersionReference
Enhancing pathogen identification through AI-assisted metagenomic sequencingversion of recordRead source
DOI: 10.3389/fmicb.2025.1634194

What is still missing

  • Comparison blocked: Section 4.3 lacks exact sample/split manifest and reference-label construction.
  • Section 4.2 five-fold procedure concerns other datasets and cannot be assigned to Table 3.
  • Do not claim the genomic experiment is absent: Section 4.3 explicitly describes it.
Search and extraction details

source concern comparison blocked

Searches

  • "PMC12493982"

Evidence locations

  • Section 4.3
  • Table 3

Strengths and limitations

Strengths and considerations

No source-reviewed explanatory claims are recorded here yet.

Limitations and conditions

  • Section 4.3 reports a sequencing experiment, but does not fix sample accessions, split membership, genomic fitting or reference-label construction. The unrelated five-fold setup in §4.2 does not resolve these protocol gaps.
    SourcesEnhancing pathogen identification through AI-assisted metagenomic sequencing · Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133
Profile review details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Stable record: reported-task-d3fd502fdc2b38

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

17 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Input: Metagenomic sequencing data and model-specific representations.","Task: The source reports a separate metagenomic taxon-detection comparison, but its executable evaluation protocol remains incomplete."]

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Computational evaluation flow

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.title

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Datasets

MetaHIT and iHMP shotgun-sequencing cohorts; the source describes expert annotations or high-confidence reference calls as ground truth without resolving their construction here.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Splits

The genomic experiment in §4.3 does not specify a sample/split manifest. The five-fold procedure in §4.2 concerns other datasets and cannot supply this missing genomic protocol.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

unreported

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Adaptation

Section 4.3 says the model is applied directly to preprocessed sequencing reads but does not specify its genomic fitting partition, checkpoint or whether MetaHIT/iHMP labels were available during fitting. The five-fold setup in §4.2 is attached to other datasets.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

§4.2–4.3, genomic sequencing experiment immediately preceding Table 3

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

unreported

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Metrics

Precision, recall, F1 and ROC-AUC for the genomic comparison.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Baselines

Kraken2 and MetaPhlAn3.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

source checked

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Leakage controls

The genomic experiment in §4.3 does not establish independence of the expert/reference-derived labels from the compared prediction systems.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

unreported

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Uncertainty

MetaHIT/iHMP Table 3 gives point precision, recall, F1 and AUC values without a replicate count or confidence-interval procedure. The ± values and five-fold evaluation elsewhere concern other datasets and cannot supply uncertainty for this sequencing comparison.

Individual claims
Enhancing pathogen identification through AI-assisted metagenomic sequencing

Original source ↗

§4.3, MetaHIT/iHMP experiment paragraph and Table 3; contrast §4.2 and Table 2

Version: version of record
Retrieved: 2026-09-16T10:41:06Z

unreported

automated source review · 2026-09-16

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: aa88de1b0f0fd7ba1fedc1074bba9ba6ce199a0b723072a04d531db4585ae77c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-task-d3fd502fdc2b38

areas
microbes-communities
tasks
pathogen detection
entity level
task
version
Not reported
task
pathogen detection
scope note
Paper-specific evaluation task; protocol completeness requires further extraction.
benchmark research
review date: 2026-09-17; status: source_concern_comparison_blocked; primary sources: expansion-p3-metagenomic-pathogens-2025; inspected locators: Section 4.3; Table 3; searched queries: "PMC12493982"; gaps: Comparison blocked: Section 4.3 lacks exact sample/split manifest and reference-label construction.; Section 4.2 five-fold procedure concerns other datasets and cannot be assigned to Table 3.; Do not claim the genomic experiment is absent: Section 4.3 explicitly describes it.; claim scope: Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.
historical missing metadata
protocol version: not_reported_in_legacy_extract; split: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
benchmark
entity classification
review date: 2026-09-17; rationale: This source-scoped record identifies the biological prediction task and holds its paper context. Preserve the existing task identity; exact split, model adaptation and scoring remain in linked evaluations or separate protocol records.; source ids: metagenomic-pathogens-2025; source locator: Methods §§4.1–4.2; Results §4.3, Table 3 and preceding paragraph; cached text lines 118–133; ambiguities: A paper- or suite-specific task may constrain some inputs or metrics; that alone does not make it interchangeable with a complete versioned protocol. No protocol equivalence is inferred.; Some legacy profile Entity type facts use the generic phrase computational evaluation protocol. That boilerplate is not sufficient to establish a single fixed protocol identity or to merge this task with another protocol record.
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