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Borzoi (paper Table 3)

Borzoi (paper Table 3). A comparator reported by the AlphaGenome authors; protocol pages specify the dataset and adaptation.

Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

9 evaluations · 11 metric rows

At a glance

Key specifications have not been extracted for this record. See the linked evaluation and sources for the reported setup.

limited source coverage · Automated source review, 2026-09-17. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 9 evaluations · 11 metric rows. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
Borzoi (paper Table 3): RNA expression correlation across genes

Compute per-track cross-gene correlation on raw log-expression and, separately, normalized/mean-centred expression.

Author-reported evaluation · Evaluation metadata: needs review

0.765 Gene TPM (cross-gene pearsonr)

Unit: correlation · Direction: higher

Aggregation: Pearson correlation across genes. Preserve raw versus normalized Table3 rows; the inspected task paragraph does not specify the weighting used to reduce all correlations to the table scalar.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J13

Source checking is not independent reproduction.

0.449 Gene TPM normalized (cross-gene pearsonr)

Unit: correlation · Direction: higher

Aggregation: Pearson correlation across genes. Preserve raw versus normalized Table3 rows; the inspected task paragraph does not specify the weighting used to reduce all correlations to the table scalar.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J15

Source checking is not independent reproduction.

Borzoi (paper Table 3): histone ChIP-seq track prediction at 32 bp

Align predicted and experimental values on the same 32-bp tracks and test intervals.

Author-reported evaluation · Evaluation metadata: needs review

0.669 pearsonr

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; group summaries derive from individual track correlations.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J34

Source checking is not independent reproduction.

Borzoi (paper Table 3): CAGE track prediction at 32 bp

Align predicted and experimental values on the same 32-bp tracks and test intervals.

Author-reported evaluation · Evaluation metadata: needs review

0.713 pearsonr

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; group summaries derive from individual track correlations.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J18

Source checking is not independent reproduction.

Borzoi (paper Table 3): RNA-seq track prediction at 32 bp

Align predicted and experimental values on the same 32-bp tracks and test intervals.

Author-reported evaluation · Evaluation metadata: needs review

0.747 pearsonr

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; group summaries derive from individual track correlations.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J12

Source checking is not independent reproduction.

Borzoi (paper Table 3): Base-resolution RNA-seq prediction

Compare base-resolution measured coverage with both predictions on normal and log1p scales, keeping these as separate endpoints.

Author-reported evaluation · Evaluation metadata: needs review

0.460 Track @1bp (normal scale pearsonr)

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; genome-track methods average individual track correlations for assay groups.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J10

Source checking is not independent reproduction.

0.750 Track @1bp (log1p scale pearsonr)

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; genome-track methods average individual track correlations for assay groups.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J11

Source checking is not independent reproduction.

Borzoi (paper Table 3): RNA expression correlation across tracks

Compute per-gene cross-track correlation on normalized, gene-mean-centred expression.

Author-reported evaluation · Evaluation metadata: needs review

0.497 Gene TPM normalized (cross-track pearsonr)

Unit: correlation · Direction: higher

Aggregation: Pearson correlation across tracks. Preserve raw versus normalized Table3 rows; the inspected task paragraph does not specify the weighting used to reduce all correlations to the table scalar.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J14

Source checking is not independent reproduction.

Borzoi (paper Table 3): TF ChIP-seq track prediction at 32 bp

Align predicted and experimental values on the same 32-bp tracks and test intervals.

Author-reported evaluation · Evaluation metadata: needs review

0.522 pearsonr

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; group summaries derive from individual track correlations.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J37

Source checking is not independent reproduction.

Borzoi (paper Table 3): ATAC track prediction at 32 bp

Align predicted and experimental values on the same 32-bp tracks and test intervals.

Author-reported evaluation · Evaluation metadata: needs review

0.549 pearsonr

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; group summaries derive from individual track correlations.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J31

Source checking is not independent reproduction.

Borzoi (paper Table 3): DNase track prediction at 32 bp

Align predicted and experimental values on the same 32-bp tracks and test intervals.

Author-reported evaluation · Evaluation metadata: needs review

0.821 pearsonr

Unit: correlation · Direction: higher

Aggregation: Pearson correlation; group summaries derive from individual track correlations.

Uncertainty: unreported

Scored: Not reported · Eligible: Not reported

source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J25

Source checking is not independent reproduction.

How it works

How this comparator was evaluated

The source table identifies Borzoi. Compare base-resolution measured coverage with both predictions on normal and log1p scales, keeping these as separate endpoints.

Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Strengths and limitations

Strengths and considerations

No source-reviewed explanatory claims are recorded here yet.

Profile review details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Stable record: alphagenome-2026-comparator-12f00a75002435bd

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-17. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Reported methodBorzoi
Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions
Exact checkpointNot established by the summary table; inspect the protocol and original implementation. · Needs further source review
Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions
Model typeNot extracted or verified for this record.
InputsNot extracted or verified for this record.
OutputsNot extracted or verified for this record.
ParametersNot extracted or verified for this record.
Training dataNot extracted or verified for this record.
Context limitsNot extracted or verified for this record.
AccessNot extracted or verified for this record.
Code licenceNot extracted or verified for this record.
Weights licenceNot extracted or verified for this record.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

15 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Reported method

Borzoi

Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Reported method

Borzoi

Individual claims
AlphaGenome Nature 2026 supplementary methods

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

Reported method

Borzoi

Individual claims
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

Exact checkpoint

Not established by the summary table; inspect the protocol and original implementation.

Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

unextracted

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Exact checkpoint

Not established by the summary table; inspect the protocol and original implementation.

Individual claims
AlphaGenome Nature 2026 supplementary methods

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

unextracted

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

Exact checkpoint

Not established by the summary table; inspect the protocol and original implementation.

Individual claims
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

unextracted

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

Limitation

A table label does not establish identity with any other catalogue configuration bearing the same name.

Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.limitations.0.text

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Limitation

A table label does not establish identity with any other catalogue configuration bearing the same name.

Individual claims
AlphaGenome Nature 2026 supplementary methods

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.limitations.0.text

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

Limitation

A table label does not establish identity with any other catalogue configuration bearing the same name.

Individual claims
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.limitations.0.text

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

How this comparator was evaluated

The source table identifies Borzoi. Compare base-resolution measured coverage with both predictions on normal and log1p scales, keeping these as separate endpoints.

Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.sections.0.body

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

3 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: alphagenome-2026-comparator-12f00a75002435bd

areas
dna-genomes
entity level
method
configuration type
reported_configuration
version
Borzoi (paper Table 3)
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: source-alphagenome-nature2026-tables; source-alphagenome-nature2026-supplementary-methods; evidence-official-56e5abfb5f12f1cd3b20; source locator: 'Suppl Table 3 Track performance'!A10:N10; Supplementary Methods pp.22,24, Gene Expression Correlation and Benchmarking Against Borzoi Track Predictions; ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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