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Configuration

CPA

CPA configuration as evaluated in GEARS Table6.

1 evaluation · 2 metric rows

Overview

CPA configuration as evaluated in GEARS Table6.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

1 evaluation · 2 metric rows. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: CPAProtocol: GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.354 ± 0.049 mse
squared_expression_units_unreported · lower

Uncertainty: type: unreported; reported spread: 0.049; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · source checked
Methods, coverage and source

CPA on GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row CPA, column MSE
Configuration: CPAProtocol: GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.440 ± 0.036 pearson_delta_expression
correlation · higher

Uncertainty: type: unreported; reported spread: 0.036; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · source checked
Methods, coverage and source

CPA on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row CPA, column Pearson DE

Source checking is not independent reproduction. Release 2026-09-23-2b89723c6dd9.

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Evidence

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Claims, original sources and review scope · Release 2026-09-23-2b89723c6dd9
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Release 2026-09-23-2b89723c6dd9 · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: gears-2023-supp-table6-method-cpa

areas
cells-spatial-multiomics
source locator
Supplementary Table6, printed p34 / PDF p35, row CPA; Supplementary Note5.
missing metadata
checkpoint revision: unreported; parameters: unextracted
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