NPT ProteinNPT
Supervised fitness predictor evaluated by the ProteinGym authors. The leading term is the input representation the paper's model type column gives.
Overview
Supervised fitness predictor evaluated by the ProteinGym authors. The leading term is the input representation the paper's model type column gives.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
Release 2026-09-17-134cd1815de8 · 8 evaluations · 8 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| NPT ProteinNPT on ProteinGym SUP-SUB-MSE-AVG: Supervised substitutions, average over splits, MSE Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-MSE-AVG: Supervised substitutions, average over splits, MSEDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.683 mse Unit: error · Direction: lower | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, average over splits, MSE) Source checking is not independent reproduction. |
| NPT ProteinNPT on ProteinGym SUP-SUB-MSE-CONTIG: Supervised substitutions, contiguous split, MSE Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-MSE-CONTIG: Supervised substitutions, contiguous split, MSEDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.820 mse Unit: error · Direction: lower | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, contiguous split, MSE) Source checking is not independent reproduction. |
| NPT ProteinNPT on ProteinGym SUP-SUB-MSE-MOD: Supervised substitutions, modulo split, MSE Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-MSE-MOD: Supervised substitutions, modulo split, MSEDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.771 mse Unit: error · Direction: lower | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, modulo split, MSE) Source checking is not independent reproduction. |
| NPT ProteinNPT on ProteinGym SUP-SUB-MSE-RAND: Supervised substitutions, random split, MSE Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-MSE-RAND: Supervised substitutions, random split, MSEDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.459 mse Unit: error · Direction: lower | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, random split, MSE) Source checking is not independent reproduction. |
| NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-AVG: Supervised substitutions, average over splits, Spearman Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-SPEARMAN-AVG: Supervised substitutions, average over splits, SpearmanDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.613 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, average over splits, Spearman) Source checking is not independent reproduction. |
| NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-CONTIG: Supervised substitutions, contiguous split, Spearman Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-SPEARMAN-CONTIG: Supervised substitutions, contiguous split, SpearmanDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.547 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, contiguous split, Spearman) Source checking is not independent reproduction. |
| NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-MOD: Supervised substitutions, modulo split, Spearman Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-SPEARMAN-MOD: Supervised substitutions, modulo split, SpearmanDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.564 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, modulo split, Spearman) Source checking is not independent reproduction. |
| NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-RAND: Supervised substitutions, random split, Spearman Configuration: NPT ProteinNPTTask: ProteinGym SUP-SUB-SPEARMAN-RAND: Supervised substitutions, random split, SpearmanDataset subset: ProteinGym substitution DMS assays (ProteinGym split) Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.730 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(NPT ProteinNPT), column(Supervised substitutions, random split, Spearman) Source checking is not independent reproduction. |
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
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Sources and history
Release 2026-09-17-134cd1815de8 · Record review: source checked
1 source records and release history
- ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Original source · Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Technical metadata and extraction receipts
Stable ID: proteingym-method-npt-proteinnpt
- areas
- proteins-complexes
- source locator
- Table 3, row(NPT ProteinNPT)
- missing metadata
- checkpoint revision: unreported; parameters: unextracted
Related records
- model: NPT ProteinNPT on ProteinGym SUP-SUB-MSE-AVG: Supervised substitutions, average over splits, MSE
- model: NPT ProteinNPT on ProteinGym SUP-SUB-MSE-CONTIG: Supervised substitutions, contiguous split, MSE
- model: NPT ProteinNPT on ProteinGym SUP-SUB-MSE-MOD: Supervised substitutions, modulo split, MSE
- model: NPT ProteinNPT on ProteinGym SUP-SUB-MSE-RAND: Supervised substitutions, random split, MSE
- model: NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-AVG: Supervised substitutions, average over splits, Spearman
- model: NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-CONTIG: Supervised substitutions, contiguous split, Spearman
- model: NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-MOD: Supervised substitutions, modulo split, Spearman
- model: NPT ProteinNPT on ProteinGym SUP-SUB-SPEARMAN-RAND: Supervised substitutions, random split, Spearman