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MDL4Microbiome

MDL4Microbiome predicts study-specific phenotype labels from several molecular summaries of metagenomic samples.

SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Introduction (paragraph 2); Methods/Generation of feature sets (paragraph 1)

1 evaluation · 1 metric row

How it worksEvaluated procedure (conceptual)
Evaluated procedure (conceptual)1. Taxonomic, genome-abundance and metabolic-functional features derived from metagenomes. Then: 2. MDL4Microbiome. Then: 3. Study phenotype classificationsEvaluated procedure (conceptual)1. Taxonomic, genome-abundance and metabolic-functional features derived from metagenomes. Then: 2. MDL4Microbiome. Then: 3. Study phenotype classificationsEvaluated procedure (conceptual)1. Taxonomic, genome-abundance and metabolic-functional features derived from metagenomes. Then: 2. MDL4Microbiome. Then: 3. Study phenotype classifications

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)

At a glance

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

Release 2026-09-17-d277315f7d76 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
MDL4Microbiome: microbiome disease-state classification

Multimodal deep learning model on colorectal-cancer versus healthy microbiome samples

Author-reported evaluation · Evaluation metadata: needs review

0.97 accuracy

Unit: fraction · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedMultimodal deep learning applied to classify healthy and disease states of human microbiome · Table 3, CRC row, MDL4Microbiome column

Source checking is not independent reproduction.

How it works

How the evaluated method works

A multimodal neural classifier combines conventional taxonomic profiles, genome-level relative abundance and metabolic-functional features.

SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)
What was evaluated

The linked evaluation record identifies MDL4Microbiome: microbiome disease-state classification. Its dataset, split, adaptation and evidence origin remain attached to the reported results.

SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · The named evaluation’s methods and comparison table; exact preserved evaluation IDs: evaluation-lit-b4-020

Strengths and limitations

Profile review details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Stable record: reported-model-e6ba198c2ac996

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Model typeStudy-specific predictive method; this record is the paper-specific evaluated configuration.
SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)
Architecture / procedureA multimodal neural classifier combines conventional taxonomic profiles, genome-level relative abundance and metabolic-functional features.
SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)
Biological inputsTaxonomic, genome-abundance and metabolic-functional features derived from metagenomes
SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Conclusion (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)
OutputsStudy phenotype classifications
SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Supplementary Information (paragraph 1); Conclusion (paragraph 2)
ParametersAn aggregate parameter total for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sources
Sources (2)Multimodal deep learning applied to classify healthy and disease states of human microbiome; DMnBI/MDL4Microbiome README.md · Methods/Data preparation and preprocessing; Methods/Generation of feature sets; Methods/Construction of multimodal deep learning model; Methods/Performance evaluation; Results/Performance evaluation with various model architectures and parameters; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision
Known versions / configurationMDL4Microbiome is the comparison-table label; that label does not specify an immutable weight revision. · Not reported in inspected sources
SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Model identification in the comparison table and corresponding Methods; immutable checkpoint revision is not supplied by the table label.
Training data / fittingDisease-associated microbiome cohorts described in the paper, evaluated with leave-one-out cross-validation.
SourcesMultimodal deep learning applied to classify healthy and disease states of human microbiome · Methods/Generation of feature sets (paragraph 1); Introduction (paragraph 3)
Context limitsA maximum input/context length for this exact evaluated configuration is not established by the inspected sources. · Not reported in inspected sources
Sources (2)Multimodal deep learning applied to classify healthy and disease states of human microbiome; DMnBI/MDL4Microbiome README.md · Methods/Data preparation and preprocessing; Methods/Generation of feature sets; Methods/Construction of multimodal deep learning model; Methods/Performance evaluation; Results/Performance evaluation with various model architectures and parameters; inspected for explicit maximum input length (dataset lengths and family-wide limits are not substituted); README.md at pinned repository revision
AccessOfficial study implementation and usage documentation: https://github.com/DMnBI/MDL4Microbiome/blob/0b2076cbd31af62224bd7a90ef0130e4cac50017/README.md. This pinned documentation revision is not automatically the evaluated weight revision.
SourcesDMnBI/MDL4Microbiome README.md · README.md; installation, model download and usage instructions
Code licenceNo explicit code licence was established from the paper’s availability statement and inspected repository-root documentation. · Not reported in inspected sources
SourcesDMnBI/MDL4Microbiome README.md · README.md and repository-root licence-file search
Weights licenceThe inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately. · Not reported in inspected sources
SourcesDMnBI/MDL4Microbiome README.md · README.md; checkpoint/access documentation and licence scope

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

21 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual input–method–output guide. Check the procedure text and linked evaluation for fitted components, additional inputs and exact settings.

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Taxonomic, genome-abundance and metabolic-functional features derived from metagenomes","MDL4Microbiome","Study phenotype classifications"]

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Evaluated procedure (conceptual)

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.diagram.title

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Model type

Study-specific predictive method; this record is the paper-specific evaluated configuration.

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Architecture / procedure

A multimodal neural classifier combines conventional taxonomic profiles, genome-level relative abundance and metabolic-functional features.

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Weights licence

The inspected model-access documentation does not explicitly identify terms for this exact evaluated checkpoint or fitted head; repository code terms are shown separately.

Individual claims
DMnBI/MDL4Microbiome README.md

Original source ↗

README.md; checkpoint/access documentation and licence scope

Version: 0b2076cbd31af62224bd7a90ef0130e4cac50017
Retrieved: 2026-09-16T19:54:18.201417+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 8737382048b17436607ae12302dfcfed021efcc39fa849d8936c6b9ac9f52d49

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Biological inputs

Taxonomic, genome-abundance and metabolic-functional features derived from metagenomes

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Conclusion (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2)

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Outputs

Study phenotype classifications

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Supplementary Information (paragraph 1); Conclusion (paragraph 2)

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

source checked

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources.

Individual claims
DMnBI/MDL4Microbiome README.md

Original source ↗

Methods/Data preparation and preprocessing; Methods/Generation of feature sets; Methods/Construction of multimodal deep learning model; Methods/Performance evaluation; Results/Performance evaluation with various model architectures and parameters; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 0b2076cbd31af62224bd7a90ef0130e4cac50017
Retrieved: 2026-09-16T19:54:18.201417+00:00

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 8737382048b17436607ae12302dfcfed021efcc39fa849d8936c6b9ac9f52d49

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Parameters

An aggregate parameter total for this exact evaluated configuration is not established by the inspected sources.

Individual claims
Multimodal deep learning applied to classify healthy and disease states of human microbiome

Original source ↗

Methods/Data preparation and preprocessing; Methods/Generation of feature sets; Methods/Construction of multimodal deep learning model; Methods/Performance evaluation; Results/Performance evaluation with various model architectures and parameters; inspected for aggregate parameter count (component sizes are not added without an exact configuration); README.md at pinned repository revision

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: PMC archival version PMC8763943.1
Retrieved: 2026-09-16T10:33:58.492Z

unreported

automated source review · 2026-09-16

Audit details

Primary full text and the available official implementation/model documentation were inspected. Explanatory claims are source-backed; unresolved exact-configuration metadata is labelled explicitly. This is automated review, not a human review or independent benchmark reproduction.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 72330eda245ac97c5de5d47a491bb86d9b8f527a03ae25fa41cae5bfb637143b

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-model-e6ba198c2ac996

areas
microbes-communities
entity level
method
version
Not reported
reported name
MDL4Microbiome
historical missing metadata
version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: mdl4microbiome-2022; source locator: Methods/Generation of feature sets (paragraph 1); Results/Performance evaluation with various model architectures and parameters (paragraph 2) | Introduction (paragraph 2); Methods/Generation of feature sets (paragraph 1); ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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