ProteinGym v1.3 AMFR stability assay, 2,972 variants
The same AMFR assay inputs used in the earlier ESM-2 evaluation, described independently of its scoring method. This additional catalogue identity does not represent another dataset or independent source.
Evaluation results
1 evaluation · 5 metric rows. Different protocols are not a single leaderboard.
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Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.514 AUC dimensionless · higher Uncertainty: Not reported Coverage: 2972/2972 | Rewire evaluation · source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.AUC |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.019 MCC dimensionless · higher Uncertainty: Not reported Coverage: 2972/2972 | Rewire evaluation · source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.MCC |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.526 NDCG dimensionless · higher Uncertainty: Not reported Coverage: 2972/2972 | Rewire evaluation · source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.NDCG |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.008 Spearman dimensionless · higher Uncertainty: Not reported Coverage: 2972/2972 | Rewire evaluation · source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.Spearman |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.087 Top_recall dimensionless · higher Uncertainty: Not reported Coverage: 2972/2972 | Rewire evaluation · source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.Top_recall |
Source checking is not independent reproduction. Release 2026-09-22-f58a0f1d267f.
Subset and evaluation context
This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
30 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.dataset_id proteingym-dms-substitutions-v1.3 Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.dataset_id proteingym-dms-substitutions-v1.3 Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.assay_sha256.AMFR_HUMAN_Tsuboyama_2023_4G3O dd911d925eca79329a496eb6cb7b181ab448e15db244daf1c1f9c01e8a704c2a Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.assay_sha256.AMFR_HUMAN_Tsuboyama_2023_4G3O dd911d925eca79329a496eb6cb7b181ab448e15db244daf1c1f9c01e8a704c2a Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.data_verification local_bytes_hashed_not_independently_source_verified Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.data_verification local_bytes_hashed_not_independently_source_verified Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.expected_hashes_checked ["AMFR_HUMAN_Tsuboyama_2023_4G3O"] Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.expected_hashes_checked ["AMFR_HUMAN_Tsuboyama_2023_4G3O"] Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.reference_sha256 a8f498011532a74aa9fe556a50555a75e928c5837d19c06a87592ae04049b308 Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.provenance.reference_sha256 a8f498011532a74aa9fe556a50555a75e928c5837d19c06a87592ae04049b308 Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
View linked audit checks and correction history
Release 2026-09-22-f58a0f1d267f · Record review: source checked
2 source records and release history
- Seeded random ranking control: report · Original source · 1663d1f04b2bbd6dfcff77fea78129d30b0de191
- Seeded random ranking control: audit · Original source · 1663d1f04b2bbd6dfcff77fea78129d30b0de191
Technical metadata and extraction receipts
Stable ID: rewire-dataset-proteingym-amfr-random-v13
- areas
- proteins-complexes
- version
- ProteinGym-v1.3
- dataset id
- proteingym-dms-substitutions-v1.3
- selected assay
- AMFR_HUMAN_Tsuboyama_2023_4G3O
- test count
- 2972
- split
- Full assay; no train/test split
- provenance
- assay sha256: AMFR HUMAN Tsuboyama 2023 4G3O: dd911d925eca79329a496eb6cb7b181ab448e15db244daf1c1f9c01e8a704c2a; data verification: local_bytes_hashed_not_independently_source_verified; expected hashes checked: AMFR_HUMAN_Tsuboyama_2023_4G3O; reference sha256: a8f498011532a74aa9fe556a50555a75e928c5837d19c06a87592ae04049b308; source url: https://github.com/OATML-Markslab/ProteinGym/tree/144fe22b07dfaeec2b366f2346203a9838a55b4c; upstream revision: 144fe22b07dfaeec2b366f2346203a9838a55b4c
- source locator
- coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256
- reuse note
- Same mutation identities, sequences, labels and source bytes as rewire-dataset-proteingym-amfr-v13; separate record avoids its ESM-specific wording.