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Evaluation

GEARS on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE

GEARS Norman2019 CPA-control comparison evaluation of GEARS on Norman2019 perturbation-response Pearson DE, scored with Pearson correlation of differential expression.

Evaluation results

1 evaluation · 1 metric rows. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: GEARSProtocol: GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.556 ± 0.030 pearson_delta_expression
correlation · higher

Uncertainty: type: unreported; reported spread: 0.030; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · source checked
Methods, coverage and source

GEARS on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Source checking is not independent reproduction. Release 2026-09-23-2b89723c6dd9.

Evaluation procedure

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Configuration
GEARS
Protocol
GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE
Dataset subset
Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
origin
Author-reported evaluation
configuration
Not reported
protocol id
gears-2023-supp-table6-task-pearson-de
metric implementation
Pearson correlation of differential expression

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Not reported
Adaptation
Not reported
Scoring implementation
Pearson correlation of differential expression

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

15 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-23-2b89723c6dd9
Property and statementOriginal source and locationReview and provenance
attributes.adaptation
Trained perturbation-response models on Norman2019; CPA+KG adds an MLP over one-hop knowledge-graph neighbors (Supplementary Note5). GEARS training hyperparameters are in Supplementary Note22. No Perturb is a no-change control.
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.adaptation

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.metric_implementation
Pearson correlation of differential expression
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.protocol_id
gears-2023-supp-table6-task-pearson-de
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.evaluation_group_id
gears-2023-supp-table6-method-gears-gears-2023-supp-table6-dataset-norman-et-al-2019-perturbation-data-used-in-gears-supplementary-table6-evaluation-setup
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.evaluation_group_id

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.evidence_overlap
One source-table comparison with two metrics per evaluated configuration. No Perturb matches Table5; these are not additional independent runs.
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.evidence_overlap

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.origin
author_reported
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.origin

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.protocol
Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.protocol

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.published_score_reproduction
false
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.published_score_reproduction

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.source_locator
Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.suite_complete
false
Context-only references
GEARS primary supplement, Table6

Original source ↗

Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.suite_complete

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-23-2b89723c6dd9 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: gears-2023-supp-table6-evaluation-gears-pearson-de

areas
cells-spatial-multiomics
tasks
Norman2019 perturbation-response Pearson DE
origin
author_reported
protocol
Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.
comparison
protocol id: gears-2023-supp-table6-task-pearson-de; metric implementation: Pearson correlation of differential expression
missing metadata
checkpoint revision: unreported; seeds: unreported; budget: unreported; split manifest: unextracted
source locator
Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE
adaptation
Trained perturbation-response models on Norman2019; CPA+KG adds an MLP over one-hop knowledge-graph neighbors (Supplementary Note5). GEARS training hyperparameters are in Supplementary Note22. No Perturb is a no-change control.
evidence overlap
One source-table comparison with two metrics per evaluated configuration. No Perturb matches Table5; these are not additional independent runs.
published score reproduction
false
suite complete
false
evaluation group id
gears-2023-supp-table6-method-gears-gears-2023-supp-table6-dataset-norman-et-al-2019-perturbation-data-used-in-gears-supplementary-table6-evaluation-setup
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