result · source checked

0.251 auprc

AbSplice: retrained AbSplice (paper Table 4): Supervised GTEx splicing-outlier prediction, auprc

Tested model: AbSplice: retrained AbSplice (paper Table 4)
Task or benchmark: Supervised GTEx splicing-outlier prediction (AlphaGenome paper)
Dataset: Supervised GTEx splicing-outlier prediction: evaluated data subset
Procedure: Fit an Explainable Boosting Classifier on the training/validation data and evaluate the held-out variants.
Evaluation: AbSplice: retrained AbSplice (paper Table 4): Supervised GTEx splicing-outlier prediction
Evidence: Author-reported evaluation · source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 4 Variant performan'!L7

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Evaluation results

Release 2026-09-17-a757f4af4277 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Evaluated configurationMetricEvidence origin

Results grouped by the exact reported evaluation
Metric and finding	Coverage and uncertainty	Evidence
AbSplice: retrained AbSplice (paper Table 4): Supervised GTEx splicing-outlier prediction Model: AbSplice: retrained AbSplice (paper Table 4) · Benchmark: Supervised GTEx splicing-outlier prediction (AlphaGenome paper) · Dataset: Supervised GTEx splicing-outlier prediction: evaluated data subset Fit an Explainable Boosting Classifier on the training/validation data and evaluate the held-out variants. Author-reported evaluation · Evaluation metadata: needs review
0.251 auprc Unit: dimensionless · Direction: higher Aggregation: Pooled auPRC across GTEx tissues after assigning positive variants their observed tissues and negatives tissues sampled to match the positive tissue distribution.	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 4 Variant performan'!L7 Source checking is not independent reproduction.

Evidence table

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-a757f4af4277
Property and statement	Original source and location	Review and provenance
Reported result 0.251 Individual claims	AlphaGenome Nature 2026 supplementary comparison tables Original source ↗ 'Suppl Table 4 Variant performan'!L7 Version: Nature version of record, 28 January 2026 Retrieved: 2026-09-17T06:31:06.887921+00:00	source checked OOXML extraction and separate automated primary-source review · 2026-09-17 author reported Audit details Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun. Field: `attributes.printed_value` Source artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx Inspected artifact Extraction artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Extraction artifact

All evidence (CSV)All evidence (JSONL)How to read the evidence

Sources and history

Release 2026-09-17-a757f4af4277 · Record review: source checked

AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied

Download this release

Technical metadata and extraction receipts

Stable ID: alphagenome-2026-result-27978a57d6a8b5ac

areas: dna-genomes
printed value: 0.251
printed value basis: Canonical stored-number transcription of a General-format cell; visible spreadsheet precision depends on column width.
numeric value: 0.251
raw xml value: 0.251
workbook number format: General
metric: auprc
metric direction: higher
unit: dimensionless
aggregation: Pooled auPRC across GTEx tissues after assigning positive variants their observed tissues and negatives tissues sampled to match the positive tissue distribution.
uncertainty: Not reported
scored count: Not reported
eligible count: Not reported
source cells: 'Suppl Table 4 Variant performan'!L7
source locator: 'Suppl Table 4 Variant performan'!L7
review: method: OOXML extraction and separate automated primary-source review; date: 2026-09-17; artifact sha256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154; retrieval url: https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41586-025-10014-0/MediaObjects/41586_2025_10014_MOESM3_ESM.xlsx; note: Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun.
missing metadata: uncertainty: unreported; scored count: unextracted; eligible count: unextracted; seeds: unreported
source warnings: None recorded

Related records

evaluation: AbSplice: retrained AbSplice (paper Table 4): Supervised GTEx splicing-outlier prediction

Suggest a correction