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DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Chromatin activity prediction, IMR90, positives only. Scored with Spearman r on ENCODE chromatin accessibility peaks in five cell lines. Rank correlation with measured accessibility among positive IMR90 peaks.

13 evaluations · 13 metric rows

Overview

Chromatin activity prediction, IMR90, positives only. Scored with Spearman r on ENCODE chromatin accessibility peaks in five cell lines. Rank correlation with measured accessibility among positive IMR90 peaks.

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Recorded evaluations

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Published comparisons

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DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

spearman_r (fraction) · Higher values are better for this metric.

Every method DART-Eval reports on Chromatin activity prediction, IMR90, positives only, scored with Spearman r on ENCODE chromatin accessibility peaks in five cell lines.

Evaluation protocol · ENCODE chromatin accessibility peaks in five cell lines (DART-Eval split)

  1. Caduceus (probed) · Configuration · Author-reported evaluation0.149
  2. DNABERT-2 (probed) · Configuration · Author-reported evaluation0.275
  3. GENA-LM (probed) · Configuration · Author-reported evaluation0.329
  4. HyenaDNA (probed) · Configuration · Author-reported evaluation0.237
  5. Mistral-DNA (probed) · Configuration · Author-reported evaluation0.244
  6. Caduceus (fine-tuned) · Configuration · Author-reported evaluation0.479
  7. DNABERT-2 (fine-tuned) · Configuration · Author-reported evaluation0.470
  8. GENA-LM (fine-tuned) · Configuration · Author-reported evaluation0.421
  9. HyenaDNA (fine-tuned) · Configuration · Author-reported evaluation0.426
  10. ChromBPNet (ab initio) · Method · Author-reported evaluation0.549

Source order is preserved. Plotted marks show point estimates; uncertainty, where reported, is retained in the printed values and table. Differences do not establish statistical significance.

DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, column(Spearman r IMR90)
Values, uncertainty and evidence
spearman_r: original source values
Tested entityPrinted valueUncertaintyEvidence
Caduceus (probed) · Configuration0.149 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed Caduceus), column(CA-SPEARMAN-IMR90)
DNABERT-2 (probed) · Configuration0.275 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed DNABERT-2), column(CA-SPEARMAN-IMR90)
GENA-LM (probed) · Configuration0.329 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed GENA-LM), column(CA-SPEARMAN-IMR90)
HyenaDNA (probed) · Configuration0.237 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed HyenaDNA), column(CA-SPEARMAN-IMR90)
Mistral-DNA (probed) · Configuration0.244 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed Mistral-DNA), column(CA-SPEARMAN-IMR90)
Nucleotide Transformer (probed) · Configuration0.270 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed NT), column(CA-SPEARMAN-IMR90)
Caduceus (fine-tuned) · Configuration0.479 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned Caduceus), column(CA-SPEARMAN-IMR90)
DNABERT-2 (fine-tuned) · Configuration0.470 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned DNABERT-2), column(CA-SPEARMAN-IMR90)
GENA-LM (fine-tuned) · Configuration0.421 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned GENA-LM), column(CA-SPEARMAN-IMR90)
HyenaDNA (fine-tuned) · Configuration0.426 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned HyenaDNA), column(CA-SPEARMAN-IMR90)
Mistral-DNA (fine-tuned) · Configuration0.302 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned Mistral-DNA), column(CA-SPEARMAN-IMR90)
Nucleotide Transformer (fine-tuned) · Configuration0.489 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned NT), column(CA-SPEARMAN-IMR90)
ChromBPNet (ab initio) · Method0.549 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Ab initio ChromBPNet), column(CA-SPEARMAN-IMR90)
Scope and limitations
  • Author-reported numbers, source checked but not independently reproduced.
  • The evaluation setting is part of the method name: a zero-shot, probed and fine-tuned run of the same model are different entries.
  • Metrics and datasets differ between tasks, so these figures cannot be averaged into one score.

Source transcription and grouping reviewed by automated source review on 2026-09-18. These experiments were not independently reproduced by rewire.

Tested entities and results

Release 2026-09-17-134cd1815de8 · 13 evaluations · 13 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
Caduceus (fine-tuned) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.479 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned Caduceus), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

Caduceus (probed) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.149 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed Caduceus), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

ChromBPNet (ab initio) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.549 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Ab initio ChromBPNet), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

DNABERT-2 (fine-tuned) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.470 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned DNABERT-2), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

DNABERT-2 (probed) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.275 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed DNABERT-2), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

GENA-LM (fine-tuned) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.421 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned GENA-LM), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

GENA-LM (probed) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.329 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed GENA-LM), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

HyenaDNA (fine-tuned) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.426 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned HyenaDNA), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

HyenaDNA (probed) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.237 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed HyenaDNA), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

Mistral-DNA (fine-tuned) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.302 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned Mistral-DNA), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

Mistral-DNA (probed) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.244 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed Mistral-DNA), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

Nucleotide Transformer (fine-tuned) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.489 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Fine-Tuned NT), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

Nucleotide Transformer (probed) on DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only

Rank correlation with measured accessibility among positive IMR90 peaks.

Author-reported evaluation · Evaluation metadata: source checked

0.270 spearman_r

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 5, row(Probed NT), column(CA-SPEARMAN-IMR90)

Source checking is not independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-134cd1815de8
Property and statementOriginal source and locationReview and provenance
Relationship: part of

discovery-benchmark-dart-eval

Individual claims
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA

Original source ↗

Table 5, column(Spearman r IMR90)

Version: 2412.05430v1
Retrieved: 2026-09-17T07:56:09.182117+00:00

source checked

automated source review · 2026-09-18

Audit details

Primary-source transcription with no human sign-off and no independent reproduction.

Field: links:part_of:discovery-benchmark-dart-eval

Claim: dart-eval-association-ca-spearman-imr90

Source artifact SHA-256: 4194b137ba55c9a2c269d119a9afec6ae1bb0feaf17d91433ae483c41221a56b

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

Release 2026-09-17-134cd1815de8 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: dart-eval-task-ca-spearman-imr90

areas
dna-genomes
tasks
Chromatin activity prediction, IMR90, positives only
metric
Spearman r
metric direction
higher
dataset
ENCODE chromatin accessibility peaks in five cell lines
protocol
Rank correlation with measured accessibility among positive IMR90 peaks.
source locator
Table 5, column(Spearman r IMR90)
comparison panels
id: dart-eval-panel-ca-spearman-imr90; title: DART-Eval CA-SPEARMAN-IMR90: Chromatin activity prediction, IMR90, positives only; protocol id: dart-eval-task-ca-spearman-imr90; dataset id: dart-eval-dataset-encode-chromatin-accessibility-peaks-in-five-cell-lines; metric: spearman_r; unit: fraction; direction: higher; result ids: dart-eval-result-caduceus-probed-ca-spearman-imr90-spearman-r; dart-eval-result-dnabert-2-probed-ca-spearman-imr90-spearman-r; dart-eval-result-gena-lm-probed-ca-spearman-imr90-spearman-r; dart-eval-result-hyenadna-probed-ca-spearman-imr90-spearman-r; dart-eval-result-mistral-dna-probed-ca-spearman-imr90-spearman-r; dart-eval-result-nucleotide-transformer-probed-ca-spearman-imr90-spearman-r; dart-eval-result-caduceus-fine-tuned-ca-spearman-imr90-spearman-r; dart-eval-result-dnabert-2-fine-tuned-ca-spearman-imr90-spearman-r; dart-eval-result-gena-lm-fine-tuned-ca-spearman-imr90-spearman-r; dart-eval-result-hyenadna-fine-tuned-ca-spearman-imr90-spearman-r; dart-eval-result-mistral-dna-fine-tuned-ca-spearman-imr90-spearman-r; dart-eval-result-nucleotide-transformer-fine-tuned-ca-spearman-imr90-spearman-r; dart-eval-result-chrombpnet-ab-initio-ca-spearman-imr90-spearman-r; source ids: evidence-expansion-p2-evidence-discovery-final-dart-4194b137ba55; source locator: Table 5, column(Spearman r IMR90); context: Every method DART-Eval reports on Chromatin activity prediction, IMR90, positives only, scored with Spearman r on ENCODE chromatin accessibility peaks in five cell lines.; caveats: Author-reported numbers, source checked but not independently reproduced.; The evaluation setting is part of the method name: a zero-shot, probed and fine-tuned run of the same model are different entries.; Metrics and datasets differ between tasks, so these figures cannot be averaged into one score.; review: method: automated_source_review; date: 2026-09-18
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