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Task

NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot

Fitness prediction on mRNA assays, zero-shot. Scored with AUC on NABench mRNA assays. Scored zero-shot across the NABench mRNA assays.

26 evaluations · 26 metric rows

Overview

Fitness prediction on mRNA assays, zero-shot. Scored with AUC on NABench mRNA assays. Scored zero-shot across the NABench mRNA assays.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluation design

Benchmarks bring together tasks and protocols. A task describes the biological question; a protocol defines a particular test.

Benchmarks

These source-backed links do not make different protocols or scores interchangeable.

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Explore all linked results

Run instructions

No runnable recipe has been reviewed for this task. Dataset access, model requirements, licences and compute requirements must be checked against its sources before execution.

A task describes a biological question. Choose a linked protocol to obtain concrete split and scoring instructions.

Published comparisons

Explore the results reported under one evaluation protocol. Each figure keeps its source, dataset and metric together; it is not a ranking across studies. The pooled view gathers every source table that reports the same metric and names what it does not hold constant.

NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot

auc (fraction) · Higher values are better for this metric.

Every method NABench reports on Fitness prediction on mRNA assays, zero-shot, scored with AUC on NABench mRNA assays.

Evaluation protocol · NABench mRNA assays (NABench split)

  1. RNA-FM · Configuration · Author-reported evaluation0.638
  2. LucaOne · Configuration · Author-reported evaluation0.638
  3. RESM · Configuration · Author-reported evaluation0.626
  4. Enformer · Configuration · Author-reported evaluation0.626
  5. GENERator-3B · Configuration · Author-reported evaluation0.630
  6. structRFM · Configuration · Author-reported evaluation0.614
  7. SPACE · Configuration · Author-reported evaluation0.583
  8. N.T.-v2-50m · Configuration · Author-reported evaluation0.526
  9. Evo_1.5_8k_base · Configuration · Author-reported evaluation0.618
  10. Evo2-7B · Configuration · Author-reported evaluation0.575
  11. Crafts · Configuration · Author-reported evaluation0.584
  12. Evo_1_8k_base · Configuration · Author-reported evaluation0.602
  13. Evo_1_8k · Configuration · Author-reported evaluation0.602
  14. BiRNA-BERT · Configuration · Author-reported evaluation0.561
  15. RNAernie · Configuration · Author-reported evaluation0.576
  16. Evo2-7B-base · Configuration · Author-reported evaluation0.553
  17. GENA-LM-large · Configuration · Author-reported evaluation0.552
  18. HyenaDNA · Configuration · Author-reported evaluation0.558
  19. RiNALMo_giga · Configuration · Author-reported evaluation0.517
  20. GenerRNA · Configuration · Author-reported evaluation0.615
  21. Dnabert · Configuration · Author-reported evaluation0.538
  22. AIDO.RNA · Configuration · Author-reported evaluation0.591
  23. LucaVirus · Configuration · Author-reported evaluation0.531
  24. N.T.-v2-500m · Configuration · Author-reported evaluation0.521
  25. GenSLM · Configuration · Author-reported evaluation0.518
  26. Dnabert_6 · Configuration · Author-reported evaluation0.518

Source order is preserved. Plotted marks show point estimates; uncertainty, where reported, is retained in the printed values and table. Differences do not establish statistical significance.

NABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, column(mRNA)
Values, uncertainty and evidence
auc: original source values
Tested entityPrinted valueUncertaintyEvidence
RNA-FM · Configuration0.638 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RNA-FM), column(mRNA)
LucaOne · Configuration0.638 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(LucaOne), column(mRNA)
RESM · Configuration0.626 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RESM), column(mRNA)
Enformer · Configuration0.626 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Enformer), column(mRNA)
GENERator-3B · Configuration0.630 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GENERator-3B), column(mRNA)
structRFM · Configuration0.614 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(structRFM), column(mRNA)
SPACE · Configuration0.583 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(SPACE), column(mRNA)
N.T.-v2-50m · Configuration0.526 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(N.T.-v2-50m), column(mRNA)
Evo_1.5_8k_base · Configuration0.618 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo_1.5_8k_base), column(mRNA)
Evo2-7B · Configuration0.575 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo2-7B), column(mRNA)
Crafts · Configuration0.584 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Crafts), column(mRNA)
Evo_1_8k_base · Configuration0.602 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo_1_8k_base), column(mRNA)
Evo_1_8k · Configuration0.602 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo_1_8k), column(mRNA)
BiRNA-BERT · Configuration0.561 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(BiRNA-BERT), column(mRNA)
RNAernie · Configuration0.576 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RNAernie), column(mRNA)
Evo2-7B-base · Configuration0.553 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo2-7B-base), column(mRNA)
GENA-LM-large · Configuration0.552 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GENA-LM-large), column(mRNA)
HyenaDNA · Configuration0.558 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(HyenaDNA), column(mRNA)
RiNALMo_giga · Configuration0.517 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RiNALMo_giga), column(mRNA)
GenerRNA · Configuration0.615 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GenerRNA), column(mRNA)
Dnabert · Configuration0.538 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Dnabert), column(mRNA)
AIDO.RNA · Configuration0.591 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(AIDO.RNA), column(mRNA)
LucaVirus · Configuration0.531 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(LucaVirus), column(mRNA)
N.T.-v2-500m · Configuration0.521 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(N.T.-v2-500m), column(mRNA)
GenSLM · Configuration0.518 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GenSLM), column(mRNA)
Dnabert_6 · Configuration0.518 fractionNot reportedAuthor-reported evaluation · source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Dnabert_6), column(mRNA)
Scope and limitations
  • Author-reported numbers, source checked but not independently reproduced.
  • Zero-shot, few-shot and supervised cross validation figures come from different protocols and are not comparable to each other.
  • The per-nucleotide-type figures and the overall figures describe the same runs at different resolutions, so they must not be combined.

Source transcription and grouping reviewed by automated source review on 2026-09-18. These experiments were not independently reproduced by rewire.

Tested entities and results

Release 2026-09-17-134cd1815de8 · 26 evaluations · 26 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
AIDO.RNA on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: AIDO.RNATask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.591 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(AIDO.RNA), column(mRNA)

Source checking is not independent reproduction.

BiRNA-BERT on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: BiRNA-BERTTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.561 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(BiRNA-BERT), column(mRNA)

Source checking is not independent reproduction.

Crafts on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: CraftsTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.584 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Crafts), column(mRNA)

Source checking is not independent reproduction.

Dnabert_6 on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: Dnabert_6Task: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.518 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Dnabert_6), column(mRNA)

Source checking is not independent reproduction.

Dnabert on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: DnabertTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.538 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Dnabert), column(mRNA)

Source checking is not independent reproduction.

Enformer on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: EnformerTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.626 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Enformer), column(mRNA)

Source checking is not independent reproduction.

Evo_1.5_8k_base on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: Evo_1.5_8k_baseTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.618 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo_1.5_8k_base), column(mRNA)

Source checking is not independent reproduction.

Evo_1_8k_base on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: Evo_1_8k_baseTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.602 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo_1_8k_base), column(mRNA)

Source checking is not independent reproduction.

Evo_1_8k on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: Evo_1_8kTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.602 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo_1_8k), column(mRNA)

Source checking is not independent reproduction.

Evo2-7B-base on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: Evo2-7B-baseTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.553 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo2-7B-base), column(mRNA)

Source checking is not independent reproduction.

Evo2-7B on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: Evo2-7BTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.575 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(Evo2-7B), column(mRNA)

Source checking is not independent reproduction.

GENA-LM-large on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: GENA-LM-largeTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.552 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GENA-LM-large), column(mRNA)

Source checking is not independent reproduction.

GENERator-3B on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: GENERator-3BTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.630 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GENERator-3B), column(mRNA)

Source checking is not independent reproduction.

GenerRNA on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: GenerRNATask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.615 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GenerRNA), column(mRNA)

Source checking is not independent reproduction.

GenSLM on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: GenSLMTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.518 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(GenSLM), column(mRNA)

Source checking is not independent reproduction.

HyenaDNA on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: HyenaDNATask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.558 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(HyenaDNA), column(mRNA)

Source checking is not independent reproduction.

LucaOne on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: LucaOneTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.638 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(LucaOne), column(mRNA)

Source checking is not independent reproduction.

LucaVirus on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: LucaVirusTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.531 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(LucaVirus), column(mRNA)

Source checking is not independent reproduction.

N.T.-v2-500m on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: N.T.-v2-500mTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.521 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(N.T.-v2-500m), column(mRNA)

Source checking is not independent reproduction.

N.T.-v2-50m on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: N.T.-v2-50mTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.526 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(N.T.-v2-50m), column(mRNA)

Source checking is not independent reproduction.

RESM on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: RESMTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.626 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RESM), column(mRNA)

Source checking is not independent reproduction.

RiNALMo_giga on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: RiNALMo_gigaTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.517 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RiNALMo_giga), column(mRNA)

Source checking is not independent reproduction.

RNA-FM on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: RNA-FMTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.638 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RNA-FM), column(mRNA)

Source checking is not independent reproduction.

RNAernie on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: RNAernieTask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.576 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(RNAernie), column(mRNA)

Source checking is not independent reproduction.

SPACE on NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot
Configuration: SPACETask: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shotDataset subset: NABench mRNA assays (NABench split)

Scored zero-shot across the NABench mRNA assays.

Author-reported evaluation · Evaluation metadata: source checked

0.583 auc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedNABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction · Table 8, row(SPACE), column(mRNA)

Source checking is not independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-134cd1815de8
Property and statementOriginal source and locationReview and provenance
Relationship: part of

discovery-benchmark-nabench

Individual claims		NABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction

Original source ↗

Table 8, column(mRNA)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.183421+00:00

source checked

automated source review · 2026-09-18

Audit details

Primary-source transcription with no human sign-off and no independent reproduction.

Field: links:part_of:discovery-benchmark-nabench

Claim: nabench-association-zs-auc-mrna

Source artifact SHA-256: fefd48d53b1a7eadf9e14db96adacc8e646304c1b592562d9f136f4508941350

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

All evidence (CSV)All evidence (JSONL)How to read the evidence

Sources and history

Release 2026-09-17-134cd1815de8 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: nabench-task-zs-auc-mrna

areas
rna-transcriptomes
tasks
Fitness prediction on mRNA assays, zero-shot
metric
AUC
metric direction
higher
dataset
NABench mRNA assays
protocol
Scored zero-shot across the NABench mRNA assays.
source locator
Table 8, column(mRNA)
comparison panels
id: nabench-panel-zs-auc-mrna; title: NABench ZS-AUC-MRNA: Fitness prediction on mRNA assays, zero-shot; protocol id: nabench-task-zs-auc-mrna; dataset id: nabench-dataset-nabench-mrna-assays; metric: auc; unit: fraction; direction: higher; result ids: nabench-result-rna-fm-zs-auc-mrna-auc; nabench-result-lucaone-zs-auc-mrna-auc; nabench-result-resm-zs-auc-mrna-auc; nabench-result-enformer-zs-auc-mrna-auc; nabench-result-generator-3b-zs-auc-mrna-auc; nabench-result-structrfm-zs-auc-mrna-auc; nabench-result-space-zs-auc-mrna-auc; nabench-result-n-t-v2-50m-zs-auc-mrna-auc; nabench-result-evo-1-5-8k-base-zs-auc-mrna-auc; nabench-result-evo2-7b-zs-auc-mrna-auc; nabench-result-crafts-zs-auc-mrna-auc; nabench-result-evo-1-8k-base-zs-auc-mrna-auc; nabench-result-evo-1-8k-zs-auc-mrna-auc; nabench-result-birna-bert-zs-auc-mrna-auc; nabench-result-rnaernie-zs-auc-mrna-auc; nabench-result-evo2-7b-base-zs-auc-mrna-auc; nabench-result-gena-lm-large-zs-auc-mrna-auc; nabench-result-hyenadna-zs-auc-mrna-auc; nabench-result-rinalmo-giga-zs-auc-mrna-auc; nabench-result-generrna-zs-auc-mrna-auc; nabench-result-dnabert-zs-auc-mrna-auc; nabench-result-aido-rna-zs-auc-mrna-auc; nabench-result-lucavirus-zs-auc-mrna-auc; nabench-result-n-t-v2-500m-zs-auc-mrna-auc; nabench-result-genslm-zs-auc-mrna-auc; nabench-result-dnabert-6-zs-auc-mrna-auc; source ids: evidence-expansion-nabench-fefd48d5; source locator: Table 8, column(mRNA); context: Every method NABench reports on Fitness prediction on mRNA assays, zero-shot, scored with AUC on NABench mRNA assays.; caveats: Author-reported numbers, source checked but not independently reproduced.; Zero-shot, few-shot and supervised cross validation figures come from different protocols and are not comparable to each other.; The per-nucleotide-type figures and the overall figures describe the same runs at different resolutions, so they must not be combined.; review: method: automated_source_review; date: 2026-09-18
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