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Task

Cross-platform scATAC cell-type annotation

Cross-platform cell annotation transfers labels between scATAC-seq reference and query datasets.

SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

2 evaluations · 2 metric rows

At a glance

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Data, procedure and scoring
PropertyDescription and evidence
DatasetsMouse brain accessibility datasets from multiple platforms and genome-reference versions.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
SplitsSource/reference and target/query domains are evaluated under platform and tissue distribution shifts.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
MetricsAccuracy and F1 for cell-type annotation, stratified by source-to-target transfer task.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
BaselinesscNym, scJoint, Cellcano, SANGO, annATAC, AtacAnnoR and MINGLE.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
Leakage controlsThis is transductive domain adaptation: both source and target cells enter the graph-training stage, while the stated classification loss uses labelled source nodes. Target-domain access is part of the protocol and should not be represented as an untouched-query inductive test.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: overall loss, source classification loss, domain-adversarial loss and Parameter settings; cached paragraphs 60–69
UncertaintyThe cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim. · Not reported in inspected sources
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
Entity typePaper-specific computational evaluation protocol.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
OrganismsMouse brain.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
AssaysSingle-cell ATAC-seq across platforms and genome-reference versions.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
Allowed inputsChromatin-accessibility representations in source/reference and target/query domains.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
AdaptationCross-platform annotation transfer compared with specialized annotation methods.
SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

How it works

How it worksComputational evaluation flow
Computational evaluation flow1. Input: Chromatin-accessibility representations in source/reference and target/query domains.. Then: 2. Evaluation: Cross-platform annotation transfer compared with specialized annotation methods.. Then: 3. Readout: Accuracy and F1 for cell-type annotation, stratified by source-to-target transfer task.Computational evaluation flow1. Input: Chromatin-accessibility representations in source/reference and target/query domains.. Then: 2. Evaluation: Cross-platform annotation transfer compared with specialized annotation methods.. Then: 3. Readout: Accuracy and F1 for cell-type annotation, stratified by source-to-target transfer task.Computational evaluation flow1. Input: Chromatin-accessibility representations in source/reference and target/query domains.. Then: 2. Evaluation: Cross-platform annotation transfer compared with specialized annotation methods.. Then: 3. Readout: Accuracy and F1 for cell-type annotation, stratified by source-to-target transfer task.

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table
Evaluation methodology

Mouse brain accessibility datasets from multiple platforms and genome-reference versions. Source/reference and target/query domains are evaluated under platform and tissue distribution shifts. Accuracy and F1 for cell-type annotation, stratified by source-to-target transfer task. scNym, scJoint, Cellcano, SANGO, annATAC, AtacAnnoR and MINGLE. The cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim.

SourcesCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Tested entities and results

Release 2026-09-17-d277315f7d76 · 2 evaluations · 2 metric rows. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
scLLMDA: Cross-platform scATAC cell-type annotation

Cross-platform reference-query cell-type annotation.

Author-reported evaluation · Evaluation metadata: needs review

0.6525 F1

Unit: unitless · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Table 2, scLLMDA row, Ref: MosA1 / Q: WholeBrainA F1 column

Source checking is not independent reproduction.

MINGLE: Cross-platform scATAC cell-type annotation

Cross-platform reference-query comparator.

Independent external evaluation · Evaluation metadata: needs review

0.6256 F1

Unit: unitless · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedCell type annotation for scATAC-seq via DNA large language model and graph domain adaptation · Table 2, MINGLE row, Ref: MosA1 / Q: WholeBrainA F1 column

Source checking is not independent reproduction.

Papers and result coverage

Last literature check: 2026-09-17. Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.

Paper or primary resourceVersionReference
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptationversion of recordRead source
DOI: 10.1371/journal.pcbi.1014226

What is still missing

  • Reference-to-query direction is part of protocol identity; reversed pairs are not replicates.
  • Inputs and adaptation differ across baselines; scJoint uses scATAC at both stages and Cellcano follows its original target-size-dependent rounds.
  • No uncertainty in tables; F1 and accuracy printed separately, including slash-joined Table 3 cells.
Search and extraction details

primary comparison table screened

Searches

  • "PMC13132462"

Evidence locations

  • Tables 2–3
  • Methods: Benchmark methods

Strengths and limitations

Strengths and considerations

No source-reviewed explanatory claims are recorded here yet.

Limitations and conditions

Profile review details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Stable record: reported-task-d82b6284f3f431

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

17 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Input: Chromatin-accessibility representations in source/reference and target/query domains.","Evaluation: Cross-platform annotation transfer compared with specialized annotation methods.","Readout: Accuracy and F1 for cell-type annotation, stratified by source-to-target transfer task."]

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Computational evaluation flow

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.title

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Datasets

Mouse brain accessibility datasets from multiple platforms and genome-reference versions.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Splits

Source/reference and target/query domains are evaluated under platform and tissue distribution shifts.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Adaptation

Cross-platform annotation transfer compared with specialized annotation methods.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Metrics

Accuracy and F1 for cell-type annotation, stratified by source-to-target transfer task.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Baselines

scNym, scJoint, Cellcano, SANGO, annATAC, AtacAnnoR and MINGLE.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Leakage controls

This is transductive domain adaptation: both source and target cells enter the graph-training stage, while the stated classification loss uses labelled source nodes. Target-domain access is part of the protocol and should not be represented as an untouched-query inductive test.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: overall loss, source classification loss, domain-adversarial loss and Parameter settings; cached paragraphs 60–69

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Uncertainty

The cited text-accessible evaluation sections give no confidence-interval, resampling or repeat-run error-bar specification. Image-only tables and uninspected supplements are outside this absence claim.

Individual claims
Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

Original source ↗

Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table

Version: version of record
Retrieved: 2026-09-16T10:44:03.395850+00:00

unreported

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: f1cdc7d54c6b2d491e4a74a44a1188a3679c555262c988e95a1c0de4614fe3cb

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-task-d82b6284f3f431

areas
cells-tissues
tasks
Cross-platform scATAC cell-type annotation
entity level
task
version
Not reported
task
Cross-platform scATAC cell-type annotation
scope note
Paper-specific evaluation task; protocol completeness requires further extraction.
benchmark research
review date: 2026-09-17; status: primary_comparison_table_screened; primary sources: expansion-p3-scatac-llmda-2026; inspected locators: Tables 2–3; Methods: Benchmark methods; searched queries: "PMC13132462"; gaps: Reference-to-query direction is part of protocol identity; reversed pairs are not replicates.; Inputs and adaptation differ across baselines; scJoint uses scATAC at both stages and Cellcano follows its original target-size-dependent rounds.; No uncertainty in tables; F1 and accuracy printed separately, including slash-joined Table 3 cells.; claim scope: Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.
historical missing metadata
protocol version: not_reported_in_legacy_extract; split: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
benchmark
entity classification
review date: 2026-09-17; rationale: This source-scoped record identifies the biological prediction task and holds its paper context. Preserve the existing task identity; exact split, model adaptation and scoring remain in linked evaluations or separate protocol records.; source ids: scatac-llmda-2026; source locator: Methods: Benchmark datasets; Benchmark methods; Problem definition; cached text lines 9–17; task metric definitions and corresponding results table; ambiguities: A paper- or suite-specific task may constrain some inputs or metrics; that alone does not make it interchangeable with a complete versioned protocol. No protocol equivalence is inferred.; Some legacy profile Entity type facts use the generic phrase computational evaluation protocol. That boilerplate is not sufficient to establish a single fixed protocol identity or to merge this task with another protocol record.
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