rewire.it
Task

Hierarchical metagenomic taxonomy classification

Hierarchical taxonomic classification evaluates sequence labels under separate in-distribution and out-of-distribution settings.

SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

2 evaluations · 2 metric rows

At a glance

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Data, procedure and scoring
PropertyDescription and evidence
DatasetsBERTax-derived ID, OOD and Complete datasets spanning major taxonomic groups.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
SplitsID reserves 2,000 sequences per phylum for testing and uses the rest for training. OOD assigns every sequence in a genus to a single side of the train/test partition. The Complete-dataset classifier is a separate setting.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · §3.1 Datasets; Fig.2 caption (a–c)
MetricsAccuracy and macro average precision at superkingdom and phylum levels; micro/macro AUC appears in supplements.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
BaselinesMMseqs2, Minimap2, Kraken2, sourmash, MetaPhlAn4, CAT, DeepMicrobes and BERTax.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
Leakage controlsFigure 2 defines ID testing by sampling sequences within phyla, while OOD places all sequences from a genus wholly in training or wholly in testing. The same genome collection is partitioned differently, so ID scores do not establish performance on unseen genera.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · §3.1 Datasets; full-XML Fig.2 caption (a–c)
UncertaintyThe paper gives bootstrap confidence intervals for accuracy and average precision on both ID and OOD datasets.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
Entity typePaper-specific computational evaluation protocol.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
OrganismsMajor taxonomic groups in BERTax-derived ID/OOD datasets.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
AssaysReference sequence/taxonomy annotations.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
Allowed inputsDNA sequence fragments.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
AdaptationSupervised hierarchical classification tested in in-distribution and out-of-distribution regimes.
SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

How it works

How it worksComputational evaluation flow
Computational evaluation flow1. Input: DNA sequence fragments.. Then: 2. Evaluation: Supervised hierarchical classification tested in in-distribution and out-of-distribution regimes.. Then: 3. Readout: Accuracy and macro average precision at superkingdom and phylum levels; micro/macro AUC appears in supplements.Computational evaluation flow1. Input: DNA sequence fragments.. Then: 2. Evaluation: Supervised hierarchical classification tested in in-distribution and out-of-distribution regimes.. Then: 3. Readout: Accuracy and macro average precision at superkingdom and phylum levels; micro/macro AUC appears in supplements.Computational evaluation flow1. Input: DNA sequence fragments.. Then: 2. Evaluation: Supervised hierarchical classification tested in in-distribution and out-of-distribution regimes.. Then: 3. Readout: Accuracy and macro average precision at superkingdom and phylum levels; micro/macro AUC appears in supplements.

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages
Evaluation methodology

BERTax-derived ID, OOD and Complete datasets spanning major taxonomic groups. Accuracy and macro average precision at superkingdom and phylum levels; micro/macro AUC appears in supplements. MMseqs2, Minimap2, Kraken2, sourmash, MetaPhlAn4, CAT, DeepMicrobes and BERTax.

SourcesICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages; Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages; Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Tested entities and results

Release 2026-09-17-d277315f7d76 · 2 evaluations · 2 metric rows. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
ICCTax: Hierarchical metagenomic taxonomy classification

Macro average precision at genus rank on Complete dataset.

Author-reported evaluation · Evaluation metadata: needs review

67.20 Genus macro AveP

Unit: % · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Table 2, ICCTax row, Genus column

Source checking is not independent reproduction.

Kraken2: Hierarchical metagenomic taxonomy classification

Macro average precision at genus rank on Complete dataset.

Independent external evaluation · Evaluation metadata: needs review

70.56 Genus macro AveP

Unit: % · Direction: unknown

Uncertainty: not reported in legacy extract

Scored: Not reported · Eligible: Not reported

source checkedICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model · Table 2, Kraken2 row, Genus column

Source checking is not independent reproduction.

Papers and result coverage

Last literature check: 2026-09-17. Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.

Paper or primary resourceVersionReference
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language modelversion of recordRead source
DOI: 10.1093/bioadv/vbaf257

What is still missing

  • MetaPhlAn4 uses its official prebuilt database, unlike the common training database; preserve the asterisk.
  • CAT and MetaPhlAn4 do not supply probabilities, so AveP is inapplicable, not zero.
  • Bootstrap intervals exist in supplemental figures; main-table values lack printed intervals.
Search and extraction details

primary comparison table screened

Searches

  • "PMC12619997"

Evidence locations

  • Tables 1–2 and footnotes
  • Section 3.2.1
  • Supplement Figures S3–S4 (interval locations)

Strengths and limitations

Strengths and considerations

No source-reviewed explanatory claims are recorded here yet.

Profile review details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Stable record: reported-task-f4b1c9373f0929

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

17 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statementOriginal source and locationReview and provenance
Diagram caption

Conceptual summary of the cited evaluation; exact task configuration and source version remain part of the protocol.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.caption

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram steps

["Input: DNA sequence fragments.","Evaluation: Supervised hierarchical classification tested in in-distribution and out-of-distribution regimes.","Readout: Accuracy and macro average precision at superkingdom and phylum levels; micro/macro AUC appears in supplements."]

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.steps

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Diagram title

Computational evaluation flow

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.diagram.title

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Datasets

BERTax-derived ID, OOD and Complete datasets spanning major taxonomic groups.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Splits

ID reserves 2,000 sequences per phylum for testing and uses the rest for training. OOD assigns every sequence in a genus to a single side of the train/test partition. The Complete-dataset classifier is a separate setting.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

§3.1 Datasets; Fig.2 caption (a–c)

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Adaptation

Supervised hierarchical classification tested in in-distribution and out-of-distribution regimes.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.10.value

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Metrics

Accuracy and macro average precision at superkingdom and phylum levels; micro/macro AUC appears in supplements.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.2.value

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Baselines

MMseqs2, Minimap2, Kraken2, sourmash, MetaPhlAn4, CAT, DeepMicrobes and BERTax.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.3.value

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Leakage controls

Figure 2 defines ID testing by sampling sequences within phyla, while OOD places all sequences from a genus wholly in training or wholly in testing. The same genome collection is partitioned differently, so ID scores do not establish performance on unseen genera.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

§3.1 Datasets; full-XML Fig.2 caption (a–c)

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.4.value

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Uncertainty

The paper gives bootstrap confidence intervals for accuracy and average precision on both ID and OOD datasets.

Individual claims
ICCTax: a hierarchical taxonomic classifier for metagenomic sequences on a large language model

Original source ↗

Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages

Version: version of record
Retrieved: 2026-09-16T10:33:55.373Z

source checked

automated source review · 2026-09-16

Audit details

Relevant full-paper computational evaluation sections, tables/captions and cited supplementary task passages were reviewed. Reporting omissions are scoped to the inspected sources. Original numerical results are unchanged.

Field: attributes.profile.facts.5.value

Source artifact SHA-256: 2ce0b48f1cde3aea7e561d92f4d7dc1525af7439ccd16f80bec0773e8812c8ec

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

2 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: reported-task-f4b1c9373f0929

areas
microbes-communities
tasks
Hierarchical metagenomic taxonomy classification
entity level
task
version
Not reported
task
Hierarchical metagenomic taxonomy classification
scope note
Paper-specific evaluation task; protocol completeness requires further extraction.
benchmark research
review date: 2026-09-17; status: primary_comparison_table_screened; primary sources: expansion-p3-icctax-2025; inspected locators: Tables 1–2 and footnotes; Section 3.2.1; Supplement Figures S3–S4 (interval locations); searched queries: "PMC12619997"; gaps: MetaPhlAn4 uses its official prebuilt database, unlike the common training database; preserve the asterisk.; CAT and MetaPhlAn4 do not supply probabilities, so AveP is inapplicable, not zero.; Bootstrap intervals exist in supplemental figures; main-table values lack printed intervals.; claim scope: Primary-paper discovery and source inspection. Source-checked results are not independently reproduced experiments.
historical missing metadata
protocol version: not_reported_in_legacy_extract; split: not_reported_in_legacy_extract
metadata review scope
historical_missing_metadata preserves the original discovery state. Current descriptive evidence and missingness are recorded in profile.facts; numerical-result review is separate.
legacy kinds
benchmark
entity classification
review date: 2026-09-17; rationale: This source-scoped record identifies the biological prediction task and holds its paper context. Preserve the existing task identity; exact split, model adaptation and scoring remain in linked evaluations or separate protocol records.; source ids: icctax-2025; source locator: Results §§3.1–3.2.1; cached text lines 47–48, 51, 53–54; uncertainty/repeat-run/statistical-comparison passages; ambiguities: A paper- or suite-specific task may constrain some inputs or metrics; that alone does not make it interchangeable with a complete versioned protocol. No protocol equivalence is inferred.; Some legacy profile Entity type facts use the generic phrase computational evaluation protocol. That boilerplate is not sufficient to establish a single fixed protocol identity or to merge this task with another protocol record.
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